How dying cells prevent dangerous immune reactions

| January 8, 2020

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Dying cells in the body can keep the immune system in check, thus preventing unwanted immune responses against the body's own tissues. Scientists from the German Cancer Research Center have now identified a receptor on murine immune cells that activates this protective mechanism and can thus prevent dangerous autoimmune reactions in which the immune system attacks the patient's own body tissues. Billions of cells die every day in the human body. This occurs as part of a highly regulated process called apoptosis or programmed cell death. The dying cells confront the immune system with large amounts of proteins, which ought to activate an immune response, but the apoptotic cells seem to actively suppress the immune system so that it does not attack the body's own tissues. "We began wondering many years ago what kind of protective mechanism prevents autoimmune reactions—the body attacking its own tissues—when cells in the immune system, such as dendritic cells, take up the remains of the dead cells," Peter Krammer, an immunologist at the German Cancer Research Center (DKFZ), remarked.

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Richcore Lifesciences Pvt. Ltd. is an innovation led biotechnology company developing novel enzymatic solutions for Industrial Biotechnology and Animal Origin Free recombinant proteins and enzymes for Biopharma. Richcore is venture and PE investment backed, and has multiple patent filings, and a high capacity GMP certified manufacturing plant. Its solutions are used in the global food, water, energy, and biopharma industries. At the root of its innovation is the vision and commitment to create cleaner, greener and sustainable solutions to tackle the current industrial problems. Richcore's corporate goals are aligned with the goals of the society at large to achieve meaningful economic development. Richcore intrinsically believes that doing well happens by doing good!

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MEDICAL

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DIAGNOSTICS

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Spotlight

Richcore Lifesciences

Richcore Lifesciences Pvt. Ltd. is an innovation led biotechnology company developing novel enzymatic solutions for Industrial Biotechnology and Animal Origin Free recombinant proteins and enzymes for Biopharma. Richcore is venture and PE investment backed, and has multiple patent filings, and a high capacity GMP certified manufacturing plant. Its solutions are used in the global food, water, energy, and biopharma industries. At the root of its innovation is the vision and commitment to create cleaner, greener and sustainable solutions to tackle the current industrial problems. Richcore's corporate goals are aligned with the goals of the society at large to achieve meaningful economic development. Richcore intrinsically believes that doing well happens by doing good!

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