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    RESEARCHERS ID HOW COMMON LIVER CANCER MUTATION CHANGES CELLS

    May 24, 2019

    Researchers with the Hubrecht Institute in Utrecht, Netherlands and Radboud University in Nijmegen, Netherlands, recently developed a human model using organoids to evaluate the function of specific genes commonly mutated in liver cancer. They identified how the BAP1 gene, which is often mutated in ...

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    NOVOCURE WINS FDA APPROVAL FOR FIRST MESOTHELIOMA TREATMENT IN 15 YEARS

    May 24, 2019

    Shares of NovoCure are up more than 6% in premarket trading after the company announced it won regulatory approval for its mesothelioma treatment, NovoTTF-100L System.Novocure, based in the U.K., said the U.S. Food and Drug Administration (FDA) approved NovoTTF-100L System in combination with pemetr...

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    NEKTAR FORMS NEW SUBSIDIARY IN ANTICIPATION OF OPIOID MEDICATION APPROVAL

    May 24, 2019

    With a potential approval of an opioid molecule awaiting regulatory review, Nektar Therapeutics announced the launch of a new subsidiary, Inheris Biopharma, Inc., which will be responsible for the launch and commercialization of the opioid.NKTR-181 is a novel, first-in-class, investigational opioid ...

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    DEVICE RAPIDLY MEASURES GROWTH OF SINGLE CELLS SIMULTANEOUSLY

    May 24, 2019

    A new technique invented at MIT can precisely measure the growth of many individual cells simultaneously. The advance holds promise for fast drug tests, offers new insights into growth variation across single cells within larger populations, and helps track the dynamic growth of cells to changing en...

    BIOENGINEER.ORG
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    BICYCLE THERAPEUTICS EXPECTS TO RAISE $60.6 MILLION IN IPO

    May 23, 2019

    Bicycle Therapeutics announced the pricing of its initial public offering (IPO), offering 4,333,333 shares at an IPO price of $14 per share. The company expects to raise about $60.6 million. It is trading on the Nasdaq under the BCYC ticker symbol.The company focuses on developing a novel class of d...

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    GENE THERAPY COMPANY LOCANA EARNS $55 MILLION IN SERIES A FINANCING

    May 23, 2019

    Backed by Google and other noted venture capital companies, San Diego-based Locana, Inc.launched with $55 million in a Series A financing round that will be used to expand the company’s pipeline of RNA-targeting gene therapy programs.Locana, which was founded in 2016, will be helmed by Jeffrey...

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    AMPRION JOINS THE FIGHT AGAINST PARKINSON'S THROUGH EARLY DETECTION TESTING

    May 23, 2019

    Amprion today announced its proprietary technology, Protein Misfolding Cyclic Amplification (PMCA) using CSF and plasma alpha-Synuclein (αS) to aid in the diagnosis of Parkinson's disease, received a Breakthrough Device designation from U.S. FDA."Prions are proteins gone rogue. This i...

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    FDA PERMITS MARKETING OF FIRST DIAGNOSTIC TEST TO AID IN DETECTING PROSTHETIC JOINT INFECTIONS

    May 23, 2019

    Today, the U.S. Food and Drug Administration permitted marketing of the Synovasure Lateral Flow Test Kit as an aid for the detection of periprosthetic joint infection (infection around a joint replacement) in the synovial (lubricant) fluid of patients being evaluated for revision surgery, which is s...

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    NEW TOOL ALLOWS VIEW OF CELL DIVISION IN 3D MODELS

    May 22, 2019

    The Allen Institute for Cell Science recently launched the Integrated Mitotic Stem Cell, a new tool that visualizes mitosis. Mitosis is cell division in the typical human stem cell. It’s how a cell splits into two, duplicating all its genetic information and cellular components. The Integrated...

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    SYNLOGIC AND ROCHE PARTNER FOR IMMUNO-ONCOLOGY COMBINATION THERAPY FOR SOLID TUMORS

    May 22, 2019

    Cambridge, Mass.-based Synlogic is partnering with Roche to develop Synlogic’s SYNB1891 with Roche’s checkpoint inhibitor Tecentriq (atezolizumab) in advanced solid tumors. Synlogic plans to file an Investigational New Drug (IND) with the U.S. Food and Drug Administration (FDA) in the se...

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    IMPROVING VIRAL VECTORS FOR HEMOPHILIA GENE THERAPIES BY TRICKING THE IMMUNE SYSTEM

    May 22, 2019

    Several gene therapies in late-stage development for hemophilia use adeno-associated virus (AAV) as a vector to deliver a gene that expresses a functional coagulation factor. One limitation of this approach is that most humans have already naturally developed immunity against AAV, which can render t...

    SAN RAFFAELE TELETHON INSTITUTE
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    EVOTEC DIVERSIFIES INTO BIOLOGICS WITH $90 MILLION ACQUISITION OF JUST BIOTHERAPEUTICS

    May 22, 2019

    Germany-based Evotec SE followed up a string of collaborations with pharma companies with the $90 million acquisition of Bill & Melinda Gates Foundation-backed Just Biotherapeutics. Evotec said the all-cash deal for the Seattle-based Just.Bio will provide it with additional business opportunitie...

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