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    STUDY FINDS WAY TO POTENTIALLY IMPROVE IMMUNOTHERAPY FOR CANCER

    Feb 20, 2019

    A new study has identified a drug that potentially could make a common type of immunotherapy for cancer even more effective. The study in laboratory mice found that the drug dasatinib, which is FDA-approved to treat certain types of leukemia, greatly enhances responses to a form of immunotherapy tha...


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    PLANTS CAN SKIP THE MIDDLEMEN AND DIRECTLY RECOGNIZE DISEASE-CAUSING FUNGI

    Feb 20, 2019

    Fungal diseases collectively termed "powdery mildew" afflict a broad range of plant species, including agriculturally relevant cereals such as barley, and result in significant reductions in crop yield. Fungi that cause powdery mildew to deliver so-called effector molecules inside plant ce...


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    ESTABLISHING THE MOLECULAR BLUEPRINT OF EARLY EMBRYO DEVELOPMENT

    Feb 20, 2019

    A team of biologists, physicists and mathematical modelers in Cambridge have studied the genetic activity of over 100,000 embryonic cells to establish the molecular blueprint of mouse early embryo development. This new research provides fundamentally important information on how mammalian embryos de...


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    MASSIVE DATABASE TRACES MAMMAL ORGAN DEVELOPMENT, CELL BY SINGLE CELL

    Feb 20, 2019

    The very early days of growth, long before we are born, are a time of incredible development. In a relatively short period of time, we and other mammals create our bodies' dozens of different organs from a few thin layers of cells. In mice, that period is only four days long. In humans, it's...


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    FOREIGN BEES MONOPOLIZE PRIZE RESOURCES IN BIODIVERSITY HOTSPOT

    Feb 20, 2019

    Hike around the natural habitats of San Diego County and it becomes abundantly clear that honey bees, foreign to the area, are everywhere. In a study published last year, researchers at the University of California San Diego found that honey bees are the most widespread and abundant pollinators of w...


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    WHAT PLANT PROTEINS CAN TELL US ABOUT ALZHEIMER'S

    Feb 20, 2019

    Alzheimer's disease and other forms of dementia are a growing burden on society and a leading cause of death among the elderly. There is no cure. Salt from rising water tables and seawater intrusions are increasingly affecting crop production around the world. It's estimated that up to 50 pe...

    UNIVERSITY OF MELBOURNE
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    NEW INSIGHT ON POTENT HIV ANTIBODY COULD IMPROVE VACCINE DESIGN

    Feb 20, 2019

    In the quest to develop an effective HIV vaccine, researchers have focused attention on identifying and targeting the region of the virus's outer envelope where a lineage of antibodies are able to dock and neutralize the virus. But true to form with HIV, these broadly neutralizing antibodies, or...


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    RESEARCHERS DEFINE CELLS USED IN BONE REPAIR

    Feb 20, 2019

    Research led by Johns Hopkins investigators has uncovered the roles of two types of cells found in the vessel walls of fat tissue and described how these cells may help speed bone repair. The study found that one of these perivascular stem cell types, pericytes, induces growth of new blood vessels, ...

    JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
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TRENDING NEWS


    NOT ALL STEM CELLS ARE CREATED EQUAL, STUDY REVEALS

    Mar 22, 2019

    Researchers from the University of Toronto's Institute for Biomaterials and Biomedical Engineering (IBBME) and the Donnelly Centre have discovered a population of cells – dubbed to be "elite" – that play a key role in the process of transforming differentiated cells into st...


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    RESEARCH TEAM DEVELOPS MATERIAL TO SEPARATE OIL AND WATER FOR ENVIRONMENTAL REMEDIATION AND WASTEWATER TREATMENT

    Mar 22, 2019

    It's a popular phrase used to describe people, things, and ideas that just don't mix "like oil and water." Except it's not entirely true. Oil and water can mix and can be very difficult to completely separate when brought together. Think of environmental oil spills or wastewate...


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    MALE FISH CAN THANK GENES FOR COLOURFUL LOOKS

    Mar 22, 2019

    Striking traits seen only in males of some species – such as colorful peacock feathers or butterfly wings – are partly explained by gene behavior, research suggests. The findings aid understanding of the phenomenon, which can help animals attract mates, but also make them more vulnerable...


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    RESEARCHERS GET HUMANS TO THINK LIKE COMPUTERS

    Mar 22, 2019

    Computers, like those that power self-driving cars, can be tricked into mistaking random scribbles for trains, fences and even school busses. People aren't supposed to be able to see how those images trip up computers but in a new study, Johns Hopkins University researchers show most people actu...


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    WHEN NEURONS ARE OUT OF SHAPE, ANTIDEPRESSANTS MAY NOT WORK

    Mar 22, 2019

    Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed medication for major depressive disorder (MDD), yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD. Now, Salk Institute researchers have discovered diffe...


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    OPTICAL 'TWEEZERS' COMBINE WITH X-RAYS TO ENABLE ANALYSIS OF CRYSTALS IN LIQUIDS

    Mar 22, 2019

    Understanding how chemical reactions happen on tiny crystals in liquid solutions is central to a variety of fields, including materials synthesis and heterogeneous catalysis, but obtaining such an understanding requires that scientists observe reactions as they occur. By using coherent X-ray diffrac...


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    NEW COMPUTATIONAL TOOL COULD CHANGE HOW WE STUDY PATHOGENS

    Mar 22, 2019

    A sophisticated new analysis tool developed by Florida State University scientists may signal a new era in the study of population genetics. Their model, which incorporates advanced mathematical strategies, could help revolutionize the way researchers investigate the spread and distribution of dange...


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    ANTI-TB DRUGS CAN INCREASE RISK OF TB RE-INFECTION

    Mar 22, 2019

    Current treatments for tuberculosis (TB) are very effective in controlling TB infection caused by Mycobacterium tuberculosis (Mtb). They don't, however, always prevent reinfection. Why this happens is one of the long-standing questions in TB research. So why are our bodies unable to generate per...


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    RESEARCHERS FIND HIDDEN PROTEINS IN BACTERIA

    Mar 20, 2019

    Scientists at the University of Illinois at Chicago have developed a way to identify the beginning of every gene—known as a translation start site or a start codon—in bacterial cell DNA with a single experiment and, through this method, they have shown that an individual gene is capable ...


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    RESEARCHERS IDENTIFY GENE VARIANT ASSOCIATED WITH CELLULAR AGING

    Mar 20, 2019

    It is well known that psychiatric stress is associated with accelerated aging. Now, a new study shows that a gene mutation interacts with multiple types of psychiatric stress including post-traumatic stress disorder (PTSD), pain and sleep disturbances in association with cellular aging. The klotho g...


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    WHO PANEL CALLS FOR REGISTRY OF ALL HUMAN GENE EDITING RESEARCH

    Mar 20, 2019

    It would be irresponsible for any scientist to conduct human gene-editing studies in people, and a central registry of research plans should be set up to ensure transparency, World Health Organization experts said on Tuesday. After its first two-day meeting in Geneva, the WHO panel of gene editing e...


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    NEUTRONS PAINT ATOMIC PORTRAIT OF PROTOTYPICAL CELL SIGNALING ENZYME

    Mar 20, 2019

    Direct observations of the structure and catalytic mechanism of a prototypical kinase enzyme—protein kinase A or PKA—will provide researchers and drug developers with significantly enhanced abilities to understand and treat fatal diseases and neurological disorders such as cancer, diabet...


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SPOTLIGHT

A number of suppliers to the Life Sciences sector claim to have developed applications or solutions that are ‘compliant’ to 21CFR Part 11. Many of these are in fact only partial solutions, do not address fundamental issues of data integrity or do not provide the necessary flexibility to

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