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Assess cell viability and proliferation with colorimetric readouts ASSESS CELL VIABILITY AND PROLIFERATION WITH COLORIMETRIC READOUTS

whitepaper

Oct 29, 2019

Scientists from Molecular Devices compare an MTT assay to the colorimetric Cell Cytotoxicity Assay to assess for both experimental efficacy as well as overall workflow efficiency and time required to run the assays.

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Reliable Single Cell Cloning with Advanced Microfluidic Dispensing RELIABLE SINGLE CELL CLONING WITH ADVANCED MICROFLUIDIC DISPENSING

whitepaper

Oct 24, 2019

Find out how to accelerate and improve selective single cell cloning with advanced microfluidic dispensing.

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Adeno-Associated Virus Gene Therapy Landscape ADENO-ASSOCIATED VIRUS GENE THERAPY LANDSCAPE

whitepaper

Oct 02, 2019

Adeno-associated viruses (AAV) are virus particles composed of single-stranded DNA surrounded by a protein shell. Despite their simple structure, recombinant AAVs (rAAV) can perform the important role of delivering nucleic acids into cells during gene therapy.

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BIORESOURCE TECHNOLOGY BIORESOURCE TECHNOLOGY

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Sep 29, 2019

Bioresource Technology publishes original articles, review articles, case studies and short communications on the fundamentals, applications and management of bioresource technology.

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How to Win Biotech Funding HOW TO WIN BIOTECH FUNDING

whitepaper

Sep 27, 2019

The report provides an in-depth look at successful, proven approaches to investor presentations used today by hundreds of biotech and other life sciences executives.

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Pipetting Ergonomics PIPETTING ERGONOMICS

whitepaper

Sep 23, 2019

Areas of the body where pipetting related musculoskeletal disorders appear. Factors influencing the development of pipetting related musculoskeletal disorders. Solutions for lowering the risk for musculoskeletal disorders

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Data Integrity In The Analytical Lab DATA INTEGRITY IN THE ANALYTICAL LAB

whitepaper

Sep 18, 2019

Assurance of data integrity, security, and privacy, as required by regulators and essential for industry, is becoming more difficult for today’s bioanalytical laboratory. This challenge is compounded by the growing size and complexity of typical datasets, which have expanded to include multipl...

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The Gap Between LIMS Capabilities and QC Microbiology Needs THE GAP BETWEEN LIMS CAPABILITIES AND QC MICROBIOLOGY NEEDS

whitepaper

Sep 18, 2019

QC Microbiology challenges are immense due to sample volumes that often exceed 100,000 samples per year, with some biopharma operations reaching one million samples annually.

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BIOTECHNOLOGY ADVANCES BIOTECHNOLOGY ADVANCES

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Sep 05, 2019

Biotechnology Advances is a review journal which considers all aspects of the multidisciplinary field. The scope includes biotechnology principles and applications in industry, agriculture, medicine, environmental concerns and regulatory issues.

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Key Trends in Reshaping Future of Bio-pharmaceutical Harvest & Clarification KEY TRENDS IN RESHAPING FUTURE OF BIO-PHARMACEUTICAL HARVEST & CLARIFICATION

whitepaper

Aug 31, 2019

Bioprocess performance (efficiency, robustness, and cost) is dictated by the overall strategy chosen to implement the processing platform. The permissible strategy space itself is enabled by the performance, availability and robustness of existing bioprocess technologies. Single use systems and memb...

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Monitor cell proliferation and cell cycle in real time MONITOR CELL PROLIFERATION AND CELL CYCLE IN REAL TIME

whitepaper

Aug 29, 2019

Use real-time quantitative cell imaging assays to monitor complex effects of anti-cancer compounds in cell models.

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Cost Savings And Business Benefits Of The Madison Logic Platform COST SAVINGS AND BUSINESS BENEFITS OF THE MADISON LOGIC PLATFORM

whitepaper

Aug 29, 2019

In account-based marketing (ABM) campaigns, B2B marketers can target contacts with pinpoint accuracy through programmatic advertising. They can also create personalized content for buyers at every stage of the purchase journey. However, three challenges remain: Are businesses targeting the right con...

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CRISPR 101 CRISPR 101

whitepaper

Aug 29, 2019

Although CRISPR has now become synonymous with gene editing, it is not the first technology developed to edit DNA. 

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Challenges and Opportunities in Biotech PR CHALLENGES AND OPPORTUNITIES IN BIOTECH PR

whitepaper

Aug 27, 2019

Industry experts in biotechnology PR share their advice on communicating in a highly regulated and technical environment.

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CMC Measuring Biological Activity Of Biopharmaceuticals With Cell-Based Assays CMC MEASURING BIOLOGICAL ACTIVITY OF BIOPHARMACEUTICALS WITH CELL-BASED ASSAYS

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Aug 26, 2019

The biological activity of biopharmaceutical compounds (such as peptides, monoclonal antibodies, growth factors, and cytokines) has a direct bearing on their potency, which is a critical quality attribute and a representation of efficacy

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CRISPR Knockouts: Understanding Repair Outcomes CRISPR KNOCKOUTS: UNDERSTANDING REPAIR OUTCOMES

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Aug 23, 2019

One of the primary uses of CRISPR is to knock out genes in order to study their function. Although CRISPR enables this process by producing a double-strand break in the DNA, the subsequent repair of the break is what actually induces a knockout.

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WHY AI? HOW LANGUAGE & AI SERVICES GO HAND-IN-HAND WHY AI? HOW LANGUAGE & AI SERVICES GO HAND-IN-HAND

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Aug 21, 2019

In practice, of course, things are more complicated. Effective translation necessitates a nuanced understanding of (at least) two languages and cultures, both source and target. It requires an understanding of the original content’s goals. It mandates a fluency in tone and subtext as well as v...

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A BUYER’S GUIDE FOR LOCALIZATION SERVICES: A BUYER’S GUIDE FOR LOCALIZATION SERVICES:

whitepaper

Aug 21, 2019

Your localization partner is going to do a deep-dive into your business—so start by diving deep into theirs. Are they an industry-leader with 20 years of experience or a relative newcomer? Will they speak Samoan, Uzbek, or Swahili (and all your customers’ languages)? Can they deliver on-...

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Oxidative Stress Measurements Made Easy OXIDATIVE STRESS MEASUREMENTS MADE EASY

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Aug 16, 2019

Oxidative stress results from an imbalance between production of reactive oxygen species (ROS) and the ability of cells to scavenge them. ROS play an important role in the progression of several diseases including inflammation, atherosclerosis, aging and age-related degenerative disorders.

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Understanding Cell Death by High Content Analysis UNDERSTANDING CELL DEATH BY HIGH CONTENT ANALYSIS

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Aug 16, 2019

Cell death is a process that occurs as both a part of normal tissue homeostasis and can be aberrantly regulated in some disease states, specifically cancer.

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USING CONTENT MARKETING TO GENERATE DEMAND, CREATE NEW AUDIENCES USING CONTENT MARKETING TO GENERATE DEMAND, CREATE NEW AUDIENCES

whitepaper

Aug 14, 2019

Content—and how brands use it to interact with buyers at all stages of the engagement journey—has fundamentally reshaped every business’ go-to-market strategy. This shift has been particularly challenging for “top-of-the-funnel” demand generation marketers, most of who ...

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Automated Nucleic Acid Sample Quality Control in NGS Workflows AUTOMATED NUCLEIC ACID SAMPLE QUALITY CONTROL IN NGS WORKFLOWS

whitepaper

Jul 30, 2019

As biological molecules, DNA and RNA are fragile compounds that can undergo fast degradation if not handled with precaution and stored under optimal conditions. Poor nucleic acid sample quality may have a direct impact on the results of downstream experiments including next generation sequencing (NG...

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PTFE hose for biotechnology and pharmaceutical fluid transfers PTFE HOSE FOR BIOTECHNOLOGY AND PHARMACEUTICAL FLUID TRANSFERS

whitepaper

Jul 29, 2019

Chemically inert and easy to clean, Bioflex Ultra is a corrosion resistant hose for the pharmaceutical, food and beverage and chemical industries. This flexible hose provides reliability, performance and long service life.

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Best Practices in Microorganisms Sample Preparation with Precellys Homogenizers BEST PRACTICES IN MICROORGANISMS SAMPLE PREPARATION WITH PRECELLYS HOMOGENIZERS

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Jul 29, 2019

Microorganisms like bacteria, fungi, archaea, algae, protozoa, and viruses, known as microbes, play a critical role in many different phenomena. They are involved in climate change, nutrient cycling, biodegradation and diseases.

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A Toolkit for Emerging Biotechs A TOOLKIT FOR EMERGING BIOTECHS

whitepaper

Jul 23, 2019

Emerging biotechs are a force to be reckoned with. In 2018, approximately 70% of clinical pipelines belonged to emerging biotechs, who were also responsible for nearly 64% of new active substances approved by the FDA. In other words, 38 out of 59 approved therapies were patented by emerging biotechs...

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Small molecules 2.0: the bigger picture SMALL MOLECULES 2.0: THE BIGGER PICTURE

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Jul 18, 2019

The highest number of NCEs approved by the FDA…the fastest growing small molecule clinical pipeline reported in 20 years…the increasing numbers of small and virtual pharma taking their products further through clinical trials…these are exciting times for our industry.

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Compete Win in the Age of Account Based Buying COMPETE WIN IN THE AGE OF ACCOUNT BASED BUYING

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Jul 15, 2019

If you’re on a B2B revenue team, it’s likely your Marketing and Sales teams are experiencing some angst these days when it comes to understanding how prospects and customers want to interact with your company. On one hand customers seem to want ultra-personalized attention on every chann...

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Bio-Inert HPLC Analysis of Nucleotides BIO-INERT HPLC ANALYSIS OF NUCLEOTIDES

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Jul 15, 2019

Phosphorylated compounds such as nucleotides are known to interact with stainless steel components leading to recovery issues in HPLC and LC/MS. This Application Note describes the analysis of nucleotides using the Agilent 1260 Infinity II Bio-Inert LC System and a PEEK-lined Agilent InfinityLab Por...

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Advanced Models and Novel I/O Technologies for Preclinical PDAC Research ADVANCED MODELS AND NOVEL I/O TECHNOLOGIES FOR PRECLINICAL PDAC RESEARCH

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Jul 09, 2019

This White Paper presents orthotopic tumor homografts as a clinically-relevant pancreatic cancer preclinical model, which more accurately replicates the TME in vivo. These immunocompetent models allow advanced assessment of novel agents targeting the disease, including immunotherapies.

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The SiriusDecisions B-to-B Buying Decision Process Framework THE SIRIUSDECISIONS B-TO-B BUYING DECISION PROCESS FRAMEWORK

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Jul 08, 2019

Decisionmaking is a cognitive process defined by psychologists as the selection of a course of action from multiple alternatives (e.g. what to eat, where to shop). John Dewey, the pragmatic philosopher and psychologist, introduced the first decision process framework for consumer buying in his book ...

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Transforming the future of medical shipments TRANSFORMING THE FUTURE OF MEDICAL SHIPMENTS

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Jul 08, 2019

The cell and gene therapy space is a rapidly emerging medical market that is driving an increased number of health care shipments around the world. Given the extreme sensitivity of these shipments, transporting treatments from labs to patients has historically been a difficult task—until now. ...

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Imaging Orthotopic and Metastatic Preclinical Tumor Models IMAGING ORTHOTOPIC AND METASTATIC PRECLINICAL TUMOR MODELS

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Jul 02, 2019

Standard oncology tumor models are implanted subcutaneously. However, there are growing concerns around subcutaneous models and their predictive value due to the lack of an organ-specific tumor microenvironment (TME). This is particularly important for I/O studies, as immunotherapy response is heavi...

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Real-World Data in Gene Therapy Trials REAL-WORLD DATA IN GENE THERAPY TRIALS

whitepaper

Jul 01, 2019

This white paper explores how the analysis of real-world data can provide insight and help overcome these challenges. It also discusses some of the limitations which reduce their acceptance by the regulatory authorities.

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CRISPR-CAS9: Programming Your HealthGenetic engineering & the future of healthcare CRISPR-CAS9: PROGRAMMING YOUR HEALTHGENETIC ENGINEERING & THE FUTURE OF HEALTHCARE

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Jun 30, 2019

Genetic engineering is the deliberate modification, artificial manipulation, and recombination of the genetic material of an organism to change its characteristics. These techniques can be used as a therapy for certain diseases. This whitepaper will dive into the world of genetic engineering and its...

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Advantage of antibody based selectivity in the purification of biologics ADVANTAGE OF ANTIBODY BASED SELECTIVITY IN THE PURIFICATION OF BIOLOGICS

whitepaper

Jun 26, 2019

ADVANCES in biotherapeutics are generating an increasing range of complex molecules that present unique and often complex purification challenges.

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Ready to redefine your biomanufacturing strategy and shift to a more efficient way of biologics production? READY TO REDEFINE YOUR BIOMANUFACTURING STRATEGY AND SHIFT TO A MORE EFFICIENT WAY OF BIOLOGICS PRODUCTION?

whitepaper

Jun 26, 2019

Single-use biomanufacturing is quickly becoming the gold standard for biologics development. Greater manufacturing efficiencies coupled with increases in product quality and lower manufacturing costs have led to its adoption among the industry.

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ELECTRONIC JOURNAL OF BIOTECHNOLOGY ELECTRONIC JOURNAL OF BIOTECHNOLOGY

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Jun 26, 2019

Electronic Journal of Biotechnology is an international scientific electronic journal, which publishes papers from all areas related to Biotechnology. It covers from molecular biology and the chemistry of biological processes to aquatic and earth environmental aspects, computational applications, po...

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Incorporating Real-World Evidence Within the Label of an FDA-Approved Drug INCORPORATING REAL-WORLD EVIDENCE WITHIN THE LABEL OF AN FDA-APPROVED DRUG

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Jun 25, 2019

In today’s increasingly connected world, health care researchers have access to previously unimaginable troves of data about the effects of healthcare interventions, including medicines. New technologies are allowing researchers to use so-called “big data” to investigate ways to be...

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Genomics GENOMICS

whitepaper

Jun 25, 2019

The acquisition of the sequence is only the beginning. The sequence information provides a starting point from which the real research into the thousands of diseases that have a genetic basis can begin.

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DIRECTIVE CONSULTING PORTFOLIO DIRECTIVE CONSULTING PORTFOLIO

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Jun 24, 2019

We believe that data-driven marketing shouldn’t be confusing. Every company should know what works for their campaigns in order to make more ROI-driven decisions. At Directive, we not only craft customized campaigns for your unique marketing objectives - we exceed those objectives and truly re...

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Boosting R&D Productivity With Pooled CRISPR Screening BOOSTING R&D PRODUCTIVITY WITH POOLED CRISPR SCREENING

whitepaper

Jun 23, 2019

Pooled screening is a valuable problem-solving and cost-reduction asset at a time when pressure to conduct focused, productive pharmaceutical R&D is more intense than ever. With the emergence of CRISPR gene-editing technology, pooled screens are becoming an essential component of drug discovery ...

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Lipid–peptide bioconjugation through pyridyl disulfde reaction chemistry and its application in cell targeting and drug delivery LIPID–PEPTIDE BIOCONJUGATION THROUGH PYRIDYL DISULFDE REACTION CHEMISTRY AND ITS APPLICATION IN CELL TARGETING AND DRUG DELIVERY

whitepaper

Jun 21, 2019

The design of efficient drug delivery vectors requires versatile formulations able to simultaneously direct a multitude of molecular targets and to bypass the endosomal recycling pathway of cells.

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How Single-Cell Technologies Are Transforming Genomics and Cloning HOW SINGLE-CELL TECHNOLOGIES ARE TRANSFORMING GENOMICS AND CLONING

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Jun 21, 2019

Single-cell omics has emerged as an exciting new technology allowing for unprecedented discovery in a variety of bio-related fields. However, while there are a slew of cutting-edge products for single-cell analysis, it has become painfully clear that cell sorting and single-cell isolation could bene...

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Boosting Efficiency: Cell Culture Media Optimization BOOSTING EFFICIENCY: CELL CULTURE MEDIA OPTIMIZATION

whitepaper

Jun 21, 2019

Increased competition, the diversification of biologic drug substances, and globalization of manufacturing have accentuated the need for processes that are not only compatible with modular, flexible, smaller plants but also carry reduced total costs. Continuous and intensified processing is an attra...

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Chemical Technology and Biotechnology CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY

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Jun 13, 2019

Journal of Chemical Technology and Biotechnology (JCTB) is an international, inter-disciplinary peer-reviewed journal concerned with the application of scientific discoveries and advancements in chemical and biological technology that aim towards economically and environmentally sustainable industri...

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Increasing access to microfluidics for studying fungi and other branched biological structures INCREASING ACCESS TO MICROFLUIDICS FOR STUDYING FUNGI AND OTHER BRANCHED BIOLOGICAL STRUCTURES

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Jun 10, 2019

Microfluidic systems are well-suited for studying mixed biological communities for improving industrial processes of fermentation, biofuel production, and pharmaceutical production. The results of which have the potential to resolve the underlying mechanisms of growth and transport in these complex ...

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Exploring the Truth of Reimbursement Challenges for Cell and Gene Therapies. EXPLORING THE TRUTH OF REIMBURSEMENT CHALLENGES FOR CELL AND GENE THERAPIES.

whitepaper

Jun 10, 2019

Trinity has worked with over a third of companies with cell and gene therapies (CGTs) on market or in Phase 3 clinical trials. Our work has supported business development, launch planning, evidence generation (HEOR, etc.), market access, pricing, and other critical commercial activities to support t...

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Ultrapure water for HPLC analysis ULTRAPURE WATER FOR HPLC ANALYSIS

whitepaper

Jun 05, 2019

This whitepaper demonstrates the High Performance Liquid Chromatography (HPLC) separation and analysis technique and highlights the importance of using water of sufficient purity as an eluent and how the arium® pro VF system can facilitate this.

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Type 2 Diabetes and Management of Cardiovascular and Renal Comorbidities TYPE 2 DIABETES AND MANAGEMENT OF CARDIOVASCULAR AND RENAL COMORBIDITIES

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Jun 05, 2019

Diabetes is a chronic metabolic disorder affecting over 30 million Americans, most of whom (up to 95%) have a diagnosis of type 2 diabetes mellitus (T2D). T2D is characterized by resistance to insulin, inadequate insulin secretion, and excessive or inappropriate glucagon secretion leading to chronic...

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BioNJ white paper illustrates imbalance of costs for smaller, innovative companies BIONJ WHITE PAPER ILLUSTRATES IMBALANCE OF COSTS FOR SMALLER, INNOVATIVE COMPANIES

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Jun 05, 2019

The world’s largest biopharmaceutical companies, having a headquarters or significant presence in the Garden State, New Jersey’s life sciences ecosystem was responsible for more than 40% of all new novel FDA drug approvals over the last two years more than anyplace else in the world.

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NGS technology: Trends and clinical applications NGS TECHNOLOGY: TRENDS AND CLINICAL APPLICATIONS

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Jun 04, 2019

DNA sequencing using next-generation technologies has become established in several clinical areas over the past decade and is rapidly gaining popularity in many others. Reproductive health, oncology, Mendelian diseases, complex diseases, and infectious diseases are key areas where next-generation s...

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Best Practices with an Agilent Parallel CE System BEST PRACTICES WITH AN AGILENT PARALLEL CE SYSTEM

whitepaper

Jun 04, 2019

Quality control (QC) assessment is essential to the success of all nucleic acid workflows. Without performing reliable QC steps, the results of downstream applications can be
compromised, costing you precious time and resources.

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A Guide to Current Therapies in Immuno-Oncology A GUIDE TO CURRENT THERAPIES IN IMMUNO-ONCOLOGY

whitepaper

Jun 02, 2019

The global immuno-oncology market is expected to reach $128.3 billion by 2024. What breakthroughs have led to these incredible developments and where are we going? Take a ride on this amazing journey and download our beautiful white paper we created with the experts at Cisbio to discover the past an...

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Addressing the challenges in biologics discovery with advanced flow cytometry ADDRESSING THE CHALLENGES IN BIOLOGICS DISCOVERY WITH ADVANCED FLOW CYTOMETRY

whitepaper

May 29, 2019

Biologics represent a growing class of drugs with indications in oncology, chronic inflammation, and autoimmune diseases. However, development and production of biopharmaceuticals is expensive, time consuming, and requires a great deal of expertise.

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Industrial scale bioreactor INDUSTRIAL SCALE BIOREACTOR

whitepaper

May 28, 2019

Bioreactors and fermenters can be delivered fully automated based on our Industrial Bioprocess Automation solutions. Our scope will include not only the bioreactor itself but also auxiliary systems (media preparation, sterile dosing, CIPs) that have to be integrated for a successful qualification an...

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The Emerging Field of Exosome Research THE EMERGING FIELD OF EXOSOME RESEARCH

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May 28, 2019

Research on extracellular vesicles (EVs), particularly small EVs or exosomes, has been advancing rapidly. For years, scientists believed that exosomes were insignificant. Now it is widely acknowledged that they have an important role in mediating cell-cell communication through the transportation of...

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STRATEGIES FOR API SOLUBILITY AND BIOAVAILABILITY ENHANCEMENT STRATEGIES FOR API SOLUBILITY AND BIOAVAILABILITY ENHANCEMENT

whitepaper

May 22, 2019

The landscape of today’s drug development industry looks far different than it did only a decade ago. Innovation is creating exciting new possibilities in patient care. Improvements in synthetic chemistry and high-throughput screening have opened up the small molecule chemical space, leading t...

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Closing the Gap Between LIMS Capabilities and QC Microbiology Needs CLOSING THE GAP BETWEEN LIMS CAPABILITIES AND QC MICROBIOLOGY NEEDS

whitepaper

May 20, 2019

Organizations often overestimate the ability of laboratory information management systems (LIMS) to efficiently manage the complexities and sample volumes for a QC Microbiology operation. LIMS solutions can fail to accommodate technology advancements and regulatory changes; at least not without sign...

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Site-specific, Patient-centered and Whip-smart: Enrollment Assistants Adapt to a Shifting Landscape SITE-SPECIFIC, PATIENT-CENTERED AND WHIP-SMART: ENROLLMENT ASSISTANTS ADAPT TO A SHIFTING LANDSCAPE

whitepaper

May 20, 2019

Increasingly complex clinical trials place a tremendous burden on study sites, exacerbating already-troubling recruitment and enrollment issues. Overwhelmed, many sites may not be up to the task or have the appropriate infrastructure, creating costly delays that keep new therapies from patients. How...

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Biotech in Europe: Scaling Innovation BIOTECH IN EUROPE: SCALING INNOVATION

whitepaper

May 20, 2019

Commissioned for the 20th BioEquity Europe (May 20-21, Barcelona), this exclusive report discusses the latest trends shaping the biopharma industry in Europe.

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The Cannabis Workflow and the Importance of Temperature Control THE CANNABIS WORKFLOW AND THE IMPORTANCE OF TEMPERATURE CONTROL

whitepaper

May 17, 2019

This process uses distillation under reduced pressure. Placing a liquid mixture under vacuum enables the distillation process to occur at a lower temperature. This lowers the liquid boiling point, increases the rate of distillation and reduces exposure of temperature-sensitive components (this elimi...

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A protoplast generation and transformation A PROTOPLAST GENERATION AND TRANSFORMATION

whitepaper

May 15, 2019

Soybean production around the globe faces signifcant annual yield losses due to pests and diseases. One of the most signifcant causes of soybean yield loss annually in the U.S. is sudden death syndrome (SDS), caused by soil-borne fungi in the Fusarium solani species complex. Two of these species, F....

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Application note: Tools for 2D and 3D neuronal cell culture APPLICATION NOTE: TOOLS FOR 2D AND 3D NEURONAL CELL CULTURE

whitepaper

May 14, 2019

From the B-27 Plus Neuronal Culture System to fluorescent probes for cell analysis. Publication history of B-27 supplements demonstrates that researchers are expanding its use, far beyond the long-term culture of rat hippocampal and cortical neurons.

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The Role of the Gut Microbiome in Autoimmune Disease THE ROLE OF THE GUT MICROBIOME IN AUTOIMMUNE DISEASE

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May 02, 2019

An autoimmune disease is best described as a condition, in which the immune system mistakenly attacks healthy cells in the body. Autoimmune disease can affect any part of the body, triggering inflammation, which can lead to redness, heat, pain, and swelling.

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Cpf1 enables fast and efcient genome CPF1 ENABLES FAST AND EFCIENT GENOME

whitepaper

May 01, 2019

CRISPR technology has revolutionized fungal genetic engineering by increasing the speed and complexity of the experiments that can be performed. Moreover, the efciency of the system often allows genetic engineering to be introduced in non-model species. The efciency of CRISPR gene editing is due to ...

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Applications of Simulated Moving Bed chromatography for continuous purification of small and large molecules APPLICATIONS OF SIMULATED MOVING BED CHROMATOGRAPHY FOR CONTINUOUS PURIFICATION OF SMALL AND LARGE MOLECULES

whitepaper

Apr 30, 2019

SMB chromatography is a HPLC technique for the separation and purification of binary mixtures with high productivity and purity. The AZURA® SMB systems allow their usage in various areas such as the pharmaceutical or food industry. SMB is ideal to be used in the production of fine chemicals (sma...

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You save 80% on the continuous purification of small molecules and biomolecules YOU SAVE 80% ON THE CONTINUOUS PURIFICATION OF SMALL MOLECULES AND BIOMOLECULES

whitepaper

Apr 30, 2019

Higher productivity at significantly lower costs with Simulated Moving Bed Chromatography (SMBC)

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A Complete Solution for Lot Release and In-process Testing of Biologics in GxP Laboratories. A COMPLETE SOLUTION FOR LOT RELEASE AND IN-PROCESS TESTING OF BIOLOGICS IN GXP LABORATORIES.

whitepaper

Apr 27, 2019

Bio-Layer Interferometry (BLI) is an optical analytical technique that analyzes the interference pattern of white light reflected from two surfaces: a layer of immobilized protein on the biosensor tip and an internal reference layer.

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Merging science and art through fungi MERGING SCIENCE AND ART THROUGH FUNGI

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Apr 26, 2019

Science and art have long been studied interchangeably, with notable polymaths emerging in the Renaissance such as Leonardo da Vinci (artist, inventor, engineer and anatomist) and Alexander von Humboldt (explorer, geographer and naturalist) with his fellow investigators Johann Wolfgang von Goethe (s...

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HCA: Phenotypic fingerprint of cellular function HCA: PHENOTYPIC FINGERPRINT OF CELLULAR FUNCTION

whitepaper

Apr 25, 2019

High-content analysis app note: Phenotypic fingerprint of cellular function following gene editing by high-throughput imaging acquisition and analysis.

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Overcoming Challenges when Designing a Multicolor Flow Cytometry Panel OVERCOMING CHALLENGES WHEN DESIGNING A MULTICOLOR FLOW CYTOMETRY PANEL

whitepaper

Apr 25, 2019

Flow cytometry is a platform with the power to carry out the identification and characterization of multiple antigens at one time. At the same time, it must be noted that when more antigens and fluorochromes are employed, the experimental design becomes much more complex.

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Pharmacogenomics Testing PHARMACOGENOMICS TESTING

whitepaper

Apr 17, 2019

With 38-75 percent of medications not working as they are intended to, the reality is that a significant portion of the variation in drug reactions may be due to genetics.

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TCR sequencing solutions at MedGenome TCR SEQUENCING SOLUTIONS AT MEDGENOME

whitepaper

Apr 12, 2019

At MedGenome, we provide TCR repertoire profiling using bulk input (from cells, RNA and FFPE tissue) using the SMARTerTCR Profiling Kit (Takara Bio USA Inc) and single-cell inputs using the SMARTer single-cell TCR Profiling kit and the Chromium Immune Profiling solutions (10X Genomics).

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Benefits of Deep Learning and AI in Microscopy BENEFITS OF DEEP LEARNING AND AI IN MICROSCOPY

whitepaper

Apr 11, 2019

The white paper explains how Deep Learning Technology, neural networks and the “ground truth” open the door to label-free analysis applications. Based on a typical use case of a whole 96 well plate with variation in buffer filling level, condensation effect, meniscus-induced imaging arte...

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Gene Therapy: A Paradigm Shift in Medicine GENE THERAPY: A PARADIGM SHIFT IN MEDICINE

whitepaper

Apr 10, 2019

Gene therapy, the modification of genetic information in living cells to address a mutated gene, has the ability to dramatically change the way diseases are treated, or even cured. First conceptualized in the early 1970s, the seminal paper on the subject was published in Science by Theodore Friedman...

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Controlled, Large-Scale Manufacturing of hiPSC-Derived Cardiomyocytes in Stirred-Tank Bioreactors CONTROLLED, LARGE-SCALE MANUFACTURING OF HIPSC-DERIVED CARDIOMYOCYTES IN STIRRED-TANK BIOREACTORS

whitepaper

Apr 10, 2019

Effective drug discovery and development relies in large part on the availability of predictive preclinical model systems. Application of human cellular models from tissues which are difficult to access, such as cardiomyocytes and neurons, is still challenging. Technologies based on human induced pl...

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Environmental Biotechnology ENVIRONMENTAL BIOTECHNOLOGY

whitepaper

Apr 10, 2019

Environmental biotechnology is a system of scientific and engineering knowledge related to the use of microorganisms and their products in the prevention of environmental pollution through biotreatment of solid, liquid, and gaseous wastes, bioremediation of polluted environments, and biomonitoring o...

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GENE AND CELL THERAPY RESEARCH & DEVELOPMENT GENE AND CELL THERAPY RESEARCH & DEVELOPMENT

whitepaper

Apr 08, 2019

Gene therapy is the transfer of genetically modified materials into a patient’s tissues or cells with the goal of correcting the abnormal genes responsible for a particular disease.

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Positioning Your Biobank for Success POSITIONING YOUR BIOBANK FOR SUCCESS

whitepaper

Apr 05, 2019

The needs of a biobanking lab grow exponentially day by day, week by week, creating an urgent need for an integrated informatics platform where data can be securely and efficiently stored, retrieved, and analyzed.

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CURRENT OPINION IN BIOTECHNOLOGY CURRENT OPINION IN BIOTECHNOLOGY

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Apr 05, 2019

publishes authoritative, comprehensive, and systematic reviews. COBIOT helps specialists keep up to date with a clear and readable synthesis on current advances cell biology. Expert authors annotate the most interesting papers from the expanding volume of information published today, saving valuable...

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Best Practices for Sample Preparation and Lipid Extraction BEST PRACTICES FOR SAMPLE PREPARATION AND LIPID EXTRACTION

whitepaper

Apr 04, 2019

Lipids play a structural role in organisms, forming cells and organelles’ membranes. Due to their implication in widespread pathologies such as cancer or inflammation, they are gaining considerable interest within the scientific community.

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NEW BIOTECHNOLOGY NEW BIOTECHNOLOGY

whitepaper

Apr 02, 2019

The scope of the journal includes the research, industrial and commercial aspects of biotechnology, in areas such as: Healthcare and Pharmaceuticals; Food and Agriculture; Biofuels; Genetic Engineering and Molecular Biology; Genomics and Synthetic Biology; Nanotechnology; Environment and Biodiversit...

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Three Considerations for Successful Global Sample Processing THREE CONSIDERATIONS FOR SUCCESSFUL GLOBAL SAMPLE PROCESSING

whitepaper

Apr 02, 2019

Sample preparation and processing are often crucial components in immuno-oncology and cell and gene therapy studies. Obtaining timely and high-quality processing services is an industrywwide challenge, particularly within the context of global trials.

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A rapid CRISPR/Cas9-mediated, amplification-free target enrichment method for native-strand sequencing A RAPID CRISPR/CAS9-MEDIATED, AMPLIFICATION-FREE TARGET ENRICHMENT METHOD FOR NATIVE-STRAND SEQUENCING

whitepaper

Mar 23, 2019

Sequence selection by Cas9 provides a low-cost method of enriching native DNA from user-specified genomic loci, including regions which cannot be amplified by PCR.

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Sterilization And Biocompatiblity Of 3D-Printed Orthopedic Devices STERILIZATION AND BIOCOMPATIBLITY OF 3D-PRINTED ORTHOPEDIC DEVICES

whitepaper

Mar 22, 2019

The white paper, authored by Matthew Jorgensen, Thor Rollins and Martell Winters of Nelson Laboratories, covers these challenges and provides information on sterilizing 3D-printed orthopedic devices, differences in sterilization validation, assessing the biocompatibility, microvoids and biocompatibl...

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INTRODUCING BIO-BASED AND SUSTAINABLE COMPONENTS TO LONG-STANDING SUPPLY CHAINS. INTRODUCING BIO-BASED AND SUSTAINABLE COMPONENTS TO LONG-STANDING SUPPLY CHAINS.

whitepaper

Mar 21, 2019

Introducing bio-based and sustainable components to long-standing supply chains.

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The Missing Diversity in Human Genetic Studies THE MISSING DIVERSITY IN HUMAN GENETIC STUDIES

whitepaper

Mar 21, 2019

It has been well documented that genetic studies of human disease, especially large-scale ones, have not captured the level of diversity that exists globally, as they are predominantly based on populations of European ancestry (Popejoy and Fullerton, 2016). The under-representation of ethnically div...

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Biotech reinvented BIOTECH REINVENTED

whitepaper

Mar 20, 2019

The biotechnology industry (Biotech) is now about 30 years old – a long enough time in which to evaluate how it’s done. Unfortunately, despite some notable successes, it hasn’t completely fulfilled its promise. The business model on which Biotech has historically relied is also bre...

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Cell Growth Performance In Single-Use Bags CELL GROWTH PERFORMANCE IN SINGLE-USE BAGS

whitepaper

Mar 15, 2019

Achieving consistent cell growth is critically important to the biotech industry. To optimize the final drug product output the current industry trends are towards higher cell densities and protein titers. With the uptake of single-use bags in cell culture processes, some manufacturers have reported...

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BIOTECHNOLOGY INNOVATION BIOTECHNOLOGY INNOVATION

whitepaper

Mar 14, 2019

Modern biotechnology is a young industry. But in just over four decades, the scientists, researchers and entrepreneurs working in this field have firmly established themselves at the forefront of medical innovation. The innovations and research coming from these enterprises have led to the successfu...

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Accelerating Antibody Development with Automated Octet Assays ACCELERATING ANTIBODY DEVELOPMENT WITH AUTOMATED OCTET ASSAYS

whitepaper

Mar 11, 2019

Drug development and production is challenging, however, high throughput characterization systems can greatly accelerate discovery programs. Using a proprietary discovery and development platform technology, Avitide enables its partners to rapidly advance candidate molecules to the clinic and achiev...

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Halobacterium salinarum virus ChaoS9 HALOBACTERIUM SALINARUM VIRUS CHAOS9

whitepaper

Mar 07, 2019

The unexpected lysis of a large culture of Halobacterium salinarum strain S9 was found to be caused by a novel myovirus, designated ChaoS9. Virus purification from the culture lysate revealed a homogeneous population of caudovirus-like particles.

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CELL THERAPY: FROM RESEARCH TO COMMERCIALIZATION CELL THERAPY: FROM RESEARCH TO COMMERCIALIZATION

whitepaper

Mar 05, 2019

In cell therapy, cells are introduced into the human body to either replace endogenous dead/non-functioning cells or to modulate dysfunctional cellular mechanisms. While cell therapy has been closely linked historically to regenerative medicine, the therapeutic potential of nonprogenitor cell therap...

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Aroma in High Fat Foods by Thin Film(TF)-SPME-TD-GC/MS AROMA IN HIGH FAT FOODS BY THIN FILM(TF)-SPME-TD-GC/MS

whitepaper

Mar 04, 2019

Food product flavors are routinely monitored for quality, authenticity, and safety. The analysis may also be necessary due to off flavor or odor complaints. Aroma and flavor profiles are unique and consist of a large number of compounds spanning a wide range of concentrations, polarities, and functi...

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WHAT DO YOU WANT YOUR CELLS TO DO? TRANSFECTION 101 WHAT DO YOU WANT YOUR CELLS TO DO? TRANSFECTION 101

whitepaper

Mar 01, 2019

The ability to manipulate the genetic composition of a cell has been an integral part of life sciences research for the past several decades. Beyond furthering our understanding of the relationships between genes, proteins, and functions, it has helped shape our understanding of etiological factors ...

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More Efficient Bispecific Antibody Purification With Fewer Steps MORE EFFICIENT BISPECIFIC ANTIBODY PURIFICATION WITH FEWER STEPS

whitepaper

Feb 28, 2019

A single-step downstream process using protein A chromatography to purify a bispecific antibody (BsAb) in early screening has been successfully developed to replace an existing-three step process. The goal was to separate BsAb monomer from fragments such as the individual heavy and light chain pairs...

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BEST for QC Microbiology Training BEST FOR QC MICROBIOLOGY TRAINING

whitepaper

Feb 27, 2019

Bioburden testing is critical for monitoring water quality and raw materials and for ensuring that manufacturing processes remain in microbiological control. During the first day of the training, you will learn about Advantages and limitations of membrane filtration, How to choose the right membrane...

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Blood-based biomakers to monitor stromal conditioning in cancer BLOOD-BASED BIOMAKERS TO MONITOR STROMAL CONDITIONING IN CANCER

whitepaper

Feb 25, 2019

The concept of liquid biopsy has generated much scientific and commercial enthusiasm as it starts with a very accessible sample type - a body fluid, typically blood, rather than a surgically extracted tissue.

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Digital Twins in Healthcare DIGITAL TWINS IN HEALTHCARE

whitepaper

Feb 21, 2019

In this paper, you will learn how far we have come in generating massive amounts of patient data, but how unprepared we are to make use of it. A digital twin promises an outcome-driven approach to handling the data deluge arising from the patient’s interconnected biology, provider interactions...

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Gut bacteria influences our health from birth onwards GUT BACTERIA INFLUENCES OUR HEALTH FROM BIRTH ONWARDS

whitepaper

Feb 20, 2019

How the microbiome develops during childhood has repercussions for the rest of our lives. It influences our risk of developing allergies, intestinal illnesses and becoming overweight. Nutrition plays an important role from the outset. Polysaccharides in breast milk human milk oligosaccharides (HMO) ...

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Digital Manufacturing Of Biologics DIGITAL MANUFACTURING OF BIOLOGICS

whitepaper

Feb 19, 2019

The digital revolution in manufacturing began with an explosion in monitoring, analytics, and new computing capabilities. Combined with advances such as artificial intelligence (AI), automation, and robotics, digital is changing manufacturing concepts such as product development, factory operations,...

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Fostering Innovation in Healthcare FOSTERING INNOVATION IN HEALTHCARE

whitepaper

Feb 18, 2019

In order to compete in today’s challenging healthcare landscape, health systems must leverage new and innovative models of care delivery. The U.S. Advisory Committee on Measuring Innovation in the 21st Century Economy defines innovation as “the design, invention, development, and/or impl...

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Screening for Disease Markers Using Non-Invasive Breath Gas Analysis SCREENING FOR DISEASE MARKERS USING NON-INVASIVE BREATH GAS ANALYSIS

whitepaper

Feb 18, 2019

Over the last few years, a developing field of research has emerged in breath gas analysis of volatile organic compounds (VOCs). This technique is non-invasive and has a number of possible applications, including monitoring of metabolic processes, the study of pharmacokinetics, screening for disease...

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Accelerating Biotherapeutic Discovery ACCELERATING BIOTHERAPEUTIC DISCOVERY

whitepaper

Feb 18, 2019

A new way of thinking and working has evolved for the discovery of therapeutic antibodies. Until recently, large numbers of antibodies were generated, only for a relatively small fraction to be sampled and engineered for further lead generation. Now, Array SPR (Surface Plasmon Resonance) facilitates...

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Discovering an Antibody’s Therapeutic Fingerprint DISCOVERING AN ANTIBODY’S THERAPEUTIC FINGERPRINT

whitepaper

Feb 15, 2019

Understanding an antibody’s mechanism of action (MOA) is critical to its clinical success. Not only does MOA have a large impact on safety and efficacy, but it also influences the intellectual property (IP) and commercial potential of a therapeutic. Those antibodies with novel MOAs represent s...

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New BIO Report on Impact of Sarbanes-Oxley 404(b) on Emerging Biotech Innovators NEW BIO REPORT ON IMPACT OF SARBANES-OXLEY 404(B) ON EMERGING BIOTECH INNOVATORS

whitepaper

Feb 11, 2019

BIO is out with a new report illustrating the negative impact of Sarbanes-Oxley 404(b) on biopharmaceutical emerging growth companies (Bio-EGCs), demonstrating how this regulatory requirement harms innovation and capital formation without any corresponding investor benefit.

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Cell Therapy Logistics CELL THERAPY LOGISTICS

whitepaper

Feb 11, 2019

Much of the discussion in the cell therapy industry today focuses on the complexity of manufacturing and the unique characteristics of each dose. However, the ultimate success of a cell therapy clinical trial rests on the ability to deliver a viable, potent product to the patient. Ensuring this livi...

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Optimizing Process Efficiency In Upstream Manufacturing OPTIMIZING PROCESS EFFICIENCY IN UPSTREAM MANUFACTURING

whitepaper

Feb 08, 2019

Process efficiency is a key goal for biopharmaceutical production, focused on increasing the process' speed, keeping costs under control, and building flexibility into the process, all while maintaining the quality of the final product. In this article, several different approaches and technolog...

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Autophagy in Neurodegenerative Diseases AUTOPHAGY IN NEURODEGENERATIVE DISEASES

whitepaper

Feb 06, 2019

Neurodegenerative diseases differ substantially in their effects on various neuronal populations and brain regions, however, the accumulation of intracellular, pathogenic protein aggregates and the progressive loss of cellular function due to neuronal synaptic impairment seem to be common to all NDD...

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Upstream Bioprocessing In Food And Feed Applications UPSTREAM BIOPROCESSING IN FOOD AND FEED APPLICATIONS

whitepaper

Feb 05, 2019

Mix water and flour with a little yeast and incubate the dough in a warm place until its volume has approximately doubled“ – such household baking instructions will (or may not) produce a decent result, but are not what is needed in the industry.

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The Spectacular World of Cancer Cell Imaging THE SPECTACULAR WORLD OF CANCER CELL IMAGING

whitepaper

Feb 05, 2019

Advances in imaging techniques have been instrumental in many aspects of cancer research; from screening and diagnosis to the guidance of cancer treatments and the monitoring of its recurrence. Insights provided by these advanced imaging techniques have been pivotal in enabling scientists to make th...

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The Microbiome and Immuno-oncology THE MICROBIOME AND IMMUNO-ONCOLOGY

whitepaper

Feb 05, 2019

With a growing body of pre-clinical and clinical research, the influence of bacteria on human health and disease has emerged from the shadows and into the limelight.

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Achieving Competitive Advantage With Anatomy And Physiology ACHIEVING COMPETITIVE ADVANTAGE WITH ANATOMY AND PHYSIOLOGY

whitepaper

Feb 04, 2019

This whitepaper explores how best in class anatomy, physiology and clinical content, images, and customized solutions enable organizations to achieve strong competitive advantage, drive credibility, productivity and differentiation. We will share ideas that you can consistently apply to your own org...

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Host Cell Protein Analysis in Biologic Drug Development HOST CELL PROTEIN ANALYSIS IN BIOLOGIC DRUG DEVELOPMENT

whitepaper

Jan 26, 2019

Host cell proteins (HCPs) are common impurities in biologic drug products and are an obligatory critical quality attribute (CQA). The individual protein contaminants that make up the HCP profile, however, may vary significantly among individual biologic products and expression systems. As such, the ...

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Analyses of Large Proteins, Antibodies, and Modified Proteins Using A New Series of Advanced Large Pore HPLC Materials ANALYSES OF LARGE PROTEINS, ANTIBODIES, AND MODIFIED PROTEINS USING A NEW SERIES OF ADVANCED LARGE PORE HPLC MATERIALS

whitepaper

Jan 23, 2019

As pharmaceutical companies have shifted their development focus to large-molecule biotherapeutics, the ability to separate intact monoclonal antibodies and antibody-drug conjugates for characterization purposes have become extremely important. To enable this characterization work, new LC particle t...

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The Cellular Response to Hypoxia in Cancer White paper THE CELLULAR RESPONSE TO HYPOXIA IN CANCER WHITE PAPER

whitepaper

Jan 19, 2019

Tissue hypoxia exerts significant influence on molecular programs, cellular properties and in tumors often leads to aggressive phenotypes. HIF-1α and HIF-2α belong to the family of hypoxia inducible transcription factors and mediate cellular reprograming under low oxygen conditions. HIFs...

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Live-cell Analysis for Neuroscientists LIVE-CELL ANALYSIS FOR NEUROSCIENTISTS

whitepaper

Jan 18, 2019

Stem cell technologies using iPSCs allow researchers to create differentiated neurons and support cells to study the human brain and nervous system functions, circumventing several challenges in neurobiology research. These technologies, however, require considerable effort to build and validate cel...

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Cell Biology and Cancer CELL BIOLOGY AND CANCER

whitepaper

Jan 18, 2019

We now understand a lot about cancer. We know that it results from a series of genetic changes having to do with cell division and growth control and genetic instability, mortality, the suicide mechanism in cells; the ability of the cells to migrate; the ability of the cells to attract them a blood ...

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The essential guide to managing laboratory samples THE ESSENTIAL GUIDE TO MANAGING LABORATORY SAMPLES

whitepaper

Jan 15, 2019

This Essential Guide to Managing Laboratory Samples is a three-part white paper exploring common problems experienced in the management of samples and how, for any scale of operation, significant efficiency and accuracy benefits can be gained using dedicated sample management software.

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Advanced HDX-MS and Native-MS Approaches for Improved Biologic Candidate Selection and De-Risked CMC and Clinical Development Programs ADVANCED HDX-MS AND NATIVE-MS APPROACHES FOR IMPROVED BIOLOGIC CANDIDATE SELECTION AND DE-RISKED CMC AND CLINICAL DEVELOPMENT PROGRAMS

whitepaper

Jan 14, 2019

Despite substantial efforts utilizing a diverse set of biologic evaluation and highthroughput techniques to select candidates with the best chance of success in preclinical
development, the vast majority of biologic drug molecules fail in clinical trials. With most
biologic drugs, incl...

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How to Increase the Solubility and Bioavailable with Hot Melt Extrusion? HOW TO INCREASE THE SOLUBILITY AND BIOAVAILABLE WITH HOT MELT EXTRUSION?

whitepaper

Jan 12, 2019

Hot Melt Extrusion (HME) is an enabling processing technology that dates back many decades in the plastics, food, and other industries, and has been applied in pharmaceuticals for nearly 30 years now. Pharmaceutical manufacturers choose HME to enable poorly soluble compounds. When executed properly,...

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Maximizing Throughput for Shotgun Proteomics MAXIMIZING THROUGHPUT FOR SHOTGUN PROTEOMICS

whitepaper

Jan 12, 2019

The proteome of an organism is a dynamic entity that encompasses all expressed proteins including isoforms and modifications as well as protein-protein interactions. It has taken decades to hone the analytical methods required to measure and quantify these proteins in a rapid, reliable manner, but r...

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Why digital transformation is redefining how people, technology and devices interact in healthcare WHY DIGITAL TRANSFORMATION IS REDEFINING HOW PEOPLE, TECHNOLOGY AND DEVICES INTERACT IN HEALTHCARE

whitepaper

Jan 11, 2019

Technology touches almost every aspect of healthcare today, from how doctors interact with patients, to the way medical data is accessed and used, to the role of robotics in surgery. New technology, such as wearable devices, smartly connected implants and the Internet of Things (IoT), is making its ...

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Introduction to Machine Learning in Healthcare INTRODUCTION TO MACHINE LEARNING IN HEALTHCARE

whitepaper

Jan 10, 2019

15 minutes. That’s how long your doctor has to see you, assess your complaint, diagnose a solution and see you out the door – hopefully on the pathway back to wellness. This isn’t much time when you consider the wealth of information that he or she has to consider. Your patient rec...

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White Paper Biotechnology and Blockchain WHITE PAPER BIOTECHNOLOGY AND BLOCKCHAIN

whitepaper

Jan 08, 2019

Biotechnology is developing rapidly and even though it seemed out of focus of investors for some time, it appears to be coming back at the moment. The German government only recently launched a new bio agenda, putting forward a strong program for the next step in the biotech development. With a focu...

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Horizons in HIV Drug Development – What’s Past is Prologue HORIZONS IN HIV DRUG DEVELOPMENT – WHAT’S PAST IS PROLOGUE

whitepaper

Jan 07, 2019

To better predict the future of HIV pharmaceuticals, we must understand the past – that’s the premise behind Horizons in HIV Drug Development – What’s Past is Prologue, the free whitepaper from Citeline, part of the Informa Pharma Intelligence suite of industry intelligence s...

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Application of CRISPR/Cas to the Generation of  Genetically Engineered Mice APPLICATION OF CRISPR/CAS TO THE GENERATION OF GENETICALLY ENGINEERED MICE

whitepaper

Jan 07, 2019

Genetically engineered mice are invaluable tools for the in vivo study of gene function. The use of gene modification methods, both in embryonic stem (ES) cells and in the embryo, to modify the mouse genome has provided valuable insights into human disease and is a crucial platform for drug target d...

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Integrated Biologics: Enabling high throughput drug discovery at Amgen INTEGRATED BIOLOGICS: ENABLING HIGH THROUGHPUT DRUG DISCOVERY AT AMGEN

whitepaper

Jan 04, 2019

Large molecule discovery and development is a complex series of interwoven cycles that span many teams within a research and development organization. By making a commitment to informatics, Amgen pioneered the shift to large molecules and was on the forefront of addressing the complexity of large mo...

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Food safety and quality culture FOOD SAFETY AND QUALITY CULTURE

whitepaper

Jan 03, 2019

How to improve food safety culture? Food safety culture is a major component of food safety management systems, including ISO 22000, FSSC 22000 and BRC Food Safety Issue 8. Demonstrating improvement in food safety and quality culture is a major component of continuing food business resilience. Read ...

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Beyond Adherence to Optimal Medication Management BEYOND ADHERENCE TO OPTIMAL MEDICATION MANAGEMENT

whitepaper

Jan 02, 2019

Clinicians generally cite medication nonadherence as the primary reason patients don’t achieve treatment goals or optimal outcomes or gain control of their chronic conditions. This assertion is supported by the following data. It’s also widely recognized that about half of the medicines ...

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Cancer Research Current Trends & Future Directions CANCER RESEARCH CURRENT TRENDS & FUTURE DIRECTIONS

whitepaper

Jan 02, 2019

Throughout history, the progress of humankind can be measured by the achievements and milestones of each generation’s new knowledge discoveries and their applications. Scientists, engineers, and inventors’ contributions have impacted and in most cases improved society and the human condi...

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THE SCIENCES AND ARTS OF OPHTHALMOLOGY THE SCIENCES AND ARTS OF OPHTHALMOLOGY

whitepaper

Jan 02, 2019

This interactive course will cover basic complications all the way to nightmare situations. Having attended the course, attendees will be able to master difficult phaco cases and manage various complications.

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Galilel GALILEL

whitepaper

Jan 01, 2019

While fiat money has defined and proved economic standards for hundreds of years already, the situation with digital money is different. Digital money is a high-risk investment with unpredictable value and disappearing development teams leaving  orphaned blockchains.

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Colloidal Silica: Small Particles, Enormous Potential COLLOIDAL SILICA: SMALL PARTICLES, ENORMOUS POTENTIAL

whitepaper

Jan 01, 2019

Aqueous colloidal silica, essentially made of just sand and water, is turning up in surprising ways at the forefront of research. A new collection of case studies highlights some of the exciting ways academic researchers are using colloidal silica to expand the frontiers of materials science. Nano-z...

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Using Analytics, Machine Learning, and Simulation Technology to BETTER MANAGE PATIENT FLOW USING ANALYTICS, MACHINE LEARNING, AND SIMULATION TECHNOLOGY TO BETTER MANAGE PATIENT FLOW

whitepaper

Dec 27, 2018

MANAGING PATIENT FLOW is a growing and complex challenge for hospitals and healthcare systems of all sizes. Poor patient flow planning creates waits and delays that frustrate patients and practitioners alike, diminishes the quality of care, wastes medical resources, and costs hospitals money. H...

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Finding High Producing Clones with Monoclonality Assurance in One Day FINDING HIGH PRODUCING CLONES WITH MONOCLONALITY ASSURANCE IN ONE DAY

whitepaper

Dec 21, 2018

In the discovery and development of novel biopharmaceuticals (such as antibodies) for therapeutic use Cell Line Development is an integral process in the biomanufacturing of therapeutic proteins. Mammalian cells make ideal factories for protein production as they have similar molecular mechanisms to...

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The Insight-Driven Health Plan THE INSIGHT-DRIVEN HEALTH PLAN

whitepaper

Dec 20, 2018

In the rapidly growing Medicare Advantage market, mid-sized regional health plans must work smarter with data to compete against the major national players. Success in acquiring, retaining, and engaging members increasingly depends on deep and timely market intelligence. With Carrot MarketView Essen...

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The Road to Healthcare Value Is Driven by Quality Workforce Integration THE ROAD TO HEALTHCARE VALUE IS DRIVEN BY QUALITY WORKFORCE INTEGRATION

whitepaper

Dec 20, 2018

Regardless of different structures, geographies and populations served, organizations who become leaders in the future healthcare value economy will employ quality as a growth strategy. They will tie their success to it. In this paper, NAHQ and ACLC provide a roadmap for organizations to create a gr...

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Monitoring receptor ligand binding in living cells MONITORING RECEPTOR LIGAND BINDING IN LIVING CELLS

whitepaper

Dec 17, 2018

A number of assay techniques are used to study ligand binding to GPCRs in living cells. The most well-known being the use of radioactively labelled ligands which unfortunately, is labor intensive, needs dedicated equipment and has disposal and safety issues associated with its use. More recently FRE...

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Patient-Centered Care in Type 2 Diabetes Mellitus PATIENT-CENTERED CARE IN TYPE 2 DIABETES MELLITUS

whitepaper

Dec 14, 2018

There have been many advancements in pharmacologic agents for the treatment of type 2 diabetes mellitus (T2DM) during the past 3 decades. At the same time, evidence in support of interventional approaches, the relationship between clinical parameters and chronic complications, and effective self-man...

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Is Your Biologic At Risk For Delays, Disruptions Or Audits? IS YOUR BIOLOGIC AT RISK FOR DELAYS, DISRUPTIONS OR AUDITS?

whitepaper

Dec 13, 2018

Thus, it’s no surprise that the world’s largest pharmaceutical companies have invested a combined $1.5 billion over the past five years to focus primarily on the advance of new biologics and biosimilars. While the North American economy represents a full 40 percent of this rapidly expand...

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Living with Cancer LIVING WITH CANCER

whitepaper

Dec 13, 2018

Living with cancer is about dealing with the unknown. It is about trying to grasp the news and starting to understand its life-changing effect. It is about wondering if the treatment is working and whether the side effects will go away soon. It is about questioning whether anything else can be done ...

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Navigating Patient Payment Conversations with Financial Counseling NAVIGATING PATIENT PAYMENT CONVERSATIONS WITH FINANCIAL COUNSELING

whitepaper

Dec 12, 2018

Many healthcare organizations depend on the work of financial counselors to help patients understand both their insurance coverage and their financial obligations. These professionals help patients make smart choices by answering questions about the cost of healthcare services, setting up payment pl...

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An Innovative Approach to Manufacturing Biologics Using Microbial Fermentation AN INNOVATIVE APPROACH TO MANUFACTURING BIOLOGICS USING MICROBIAL FERMENTATION

whitepaper

Dec 12, 2018

The use of microbial fermentation to make biologics is growing rapidly. A manufacturing platform is an increasingly popular way to speed up process development stages and get a biologic to market faster. High-throughput systems can speed up the optimization of each of these platform steps. Single-us...

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Cell Therapy Today - New Developments in Immunotherapy CELL THERAPY TODAY - NEW DEVELOPMENTS IN IMMUNOTHERAPY

whitepaper

Dec 06, 2018

PHCbi brand Cell-IQ™ CO2 and O2 incubators are designed to deliver reproducibility critical to immunotherapy and regenerative medicine from one day to the next. Your desired temperature and gas concentrations replicate the in vivo model of any cell culture environment with precision and predic...

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Rare Disease Landscape: Will the Blockbuster Model Be Replaced? RARE DISEASE LANDSCAPE: WILL THE BLOCKBUSTER MODEL BE REPLACED?

whitepaper

Dec 02, 2018

With the ‘blockbuster bubble’ seemingly burst and patent protection giving way to huge rises in generic competition, the pharma industry appears to be focusing on high-value drugs for rare diseases of low prevalence for which there is a potential for rich return on investment.

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Advanced Therapeutic Antibody Discovery with Multiplexed Screening ADVANCED THERAPEUTIC ANTIBODY DISCOVERY WITH MULTIPLEXED SCREENING

whitepaper

Nov 25, 2018

Antibody-based therapeutics is the fastest growing and most successful therapeutic modality for treating numerous diseases including cancer, autoimmune disorders, and infectious disease. Multiplexed high throughput screening has become an essential component in the discovery of therapeutic antibodie...

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EPR – The ‘Workhorse Technique’ That is Still Enabling Scientists to Break New Ground After 70+ Years EPR – THE ‘WORKHORSE TECHNIQUE’ THAT IS STILL ENABLING SCIENTISTS TO BREAK NEW GROUND AFTER 70+ YEARS

whitepaper

Nov 25, 2018

A surprisingly large number of materials have unpaired electrons. These include free radicals, many transition metal ions, and defects in materials. Free radicals are often short-lived, but play crucial roles in many significant processes such as photosynthesis, oxidation, catalysis, and polymerizat...

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RADIOTHERAPY: seizing the opportunity in cancer care RADIOTHERAPY: SEIZING THE OPPORTUNITY IN CANCER CARE

whitepaper

Nov 22, 2018

The incidence of cancer is increasing, resulting in a rising demand for high‑quality cancer care. In 2018, there were close to 4.23 million new cases of cancer in Europe, and this number is predicted to rise by almost a quarter to 5.2 million by 2040.1 This growing demand poses a major challenge to ...

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Convective forces increase CXCR4-dependent glioblastoma cell invasion in GL261 murine model CONVECTIVE FORCES INCREASE CXCR4-DEPENDENT GLIOBLASTOMA CELL INVASION IN GL261 MURINE MODEL

whitepaper

Nov 19, 2018

Glioblastoma is the most common and malignant form of brain cancer. Its invasive nature limits treatment efficacy and promotes inevitable recurrence. Previous in vitro studies showed that interstitial fluid flow, a factor characteristically increased in cancer, increases glioma cell invasion through...

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GUIDE TO CANCER EARLY DIAGNOSIS GUIDE TO CANCER EARLY DIAGNOSIS

whitepaper

Nov 19, 2018

Under the terms of this license, you may copy, redistribute and adapt the work for non-commercial purposes, provided the work is appropriately cited, as indicated below. In any use of this work, there should be no suggestion that WHO endorses any specific organization, products or services. The use ...

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How cloud analytics and visualization are transforming Healthcare and Life Sciences HOW CLOUD ANALYTICS AND VISUALIZATION ARE TRANSFORMING HEALTHCARE AND LIFE SCIENCES

whitepaper

Nov 18, 2018

Healthcare and Life Sciences organizations are rapidly adopting robust data visualization and analytics capabilities. Hospitals and other healthcare providers are using analytics to identify opportunities for improvement in patient care and operational efficiencies that reduce costs. Healthcare paye...

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Emerging Liability Risks: Legionellosis EMERGING LIABILITY RISKS: LEGIONELLOSIS

whitepaper

Nov 17, 2018

Legionellosis – a bacterial infection that can cause symptoms ranging from mild flu to a deadly strain of Legionnaires’ disease (LD) – is fast emerging as a serious threat to the public and businesses. This risk bulletin reviews the current understanding of Legionella bacteria, leg...

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Using Integrated Technologies to Solve Today’s Nursing Challenges: a How-to Guide for Nurse Leaders USING INTEGRATED TECHNOLOGIES TO SOLVE TODAY’S NURSING CHALLENGES: A HOW-TO GUIDE FOR NURSE LEADERS

whitepaper

Nov 17, 2018

Integrated technologies have already begun to impact the discipline of nursing. Nurse leaders are positioned to influence how technology is applied in the patient care environment but many aren’t asking the critical questions that need to be asked or claiming their rightful seat at the table.

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Cap Inspection Provides Criticalb Information for Lab Automation CAP INSPECTION PROVIDES CRITICALB INFORMATION FOR LAB AUTOMATION

whitepaper

Nov 17, 2018

Cost containment in the healthcare system has placed clinical laboratories under constant pressure to improve efficiency while addressing patient care and safety concerns. As part of the design process, today’s instrument manufacturers seek to ensure that automation errors do not occur. A cap ...

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Accelerating Telehealth Adoption: Telemedicine’s Role in the Volume to Value Journey ACCELERATING TELEHEALTH ADOPTION: TELEMEDICINE’S ROLE IN THE VOLUME TO VALUE JOURNEY

whitepaper

Nov 16, 2018

There is growing evidence that telehealth expands access to care, improves health outcomes and healthcare quality, increases patient engagement, and reduces healthcare costs. Yet skeptics are concerned about increased utilization and lack of ROI. This URAC Industry Insight Report offers perspectives...

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Another Set of Eyes: Machine Vision Automation Solutions for In Vitro Diagnostics ANOTHER SET OF EYES: MACHINE VISION AUTOMATION SOLUTIONS FOR IN VITRO DIAGNOSTICS

whitepaper

Nov 16, 2018

Microscan at a Glance.In Vitro Diagnostics Market Introduction. Machine vision system development. Key Challenges. Lessons Learned

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Efficient Removal of Aggregates from Monoclonal Antibodies EFFICIENT REMOVAL OF AGGREGATES FROM MONOCLONAL ANTIBODIES

whitepaper

Nov 16, 2018

Monoclonal antibody (mAb) therapeutics have been widely used to treat various diseases, including cancer. Oftentimes, dimers and other high molecular weight aggregates are present in the mAb therapeutics, leading to reduced biological activity. Traditionally-used methods for aggregate removal rely h...

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MicroRNA Expression Patterns Responsible for Inducing Chemo-Resistance in Ovarian Cancer MICRORNA EXPRESSION PATTERNS RESPONSIBLE FOR INDUCING CHEMO-RESISTANCE IN OVARIAN CANCER

whitepaper

Nov 15, 2018

Despite significant progress in our understanding of the pathophysiology of cancer as a whole, ovarian cancer still remains as one of the most intractable forms of the disease with only 30% cure rate with the conventional therapy. It is also one of most common gynecologic cancer among women. One his...

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Titration and Data Integrity eBook TITRATION AND DATA INTEGRITY EBOOK

whitepaper

Nov 15, 2018

For laboratories that must comply with Good Laboratory Practices (GLP), Good Manufacturing Practices (GMP), and Good Automated Manufacturing Practices (GAMP) regulations, it is important to have records or documented evidence of all relevant analyses reviewed by a second person and readily available...

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CARING FOR QUALITY IN HEALTH CARING FOR QUALITY IN HEALTH

whitepaper

Nov 14, 2018

This synthesis report draws on key lessons from the OECD Health Care Quality Review series. As health costs continue to climb, policymakers increasingly face the challenge of ensuring that substantial spending on health is delivering value for money. At the same time, concerns about patients occasio...

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Overview of Animal-Derived Cell Culture Technology OVERVIEW OF ANIMAL-DERIVED CELL CULTURE TECHNOLOGY

whitepaper

Nov 13, 2018

Cell culture has become an indispensable technology in many branches of the life sciences. It provides the basis for studying the regulation of cell proliferation, differentiation and product formation in carefully controlled conditions, with processes and analytical tools which are scalable from th...

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Minimizing Sterile Filtration Risk Through Quality By Design MINIMIZING STERILE FILTRATION RISK THROUGH QUALITY BY DESIGN

whitepaper

Nov 13, 2018

Controlling bioburden throughout biomanufacturing processes is critical to assuring drug products are safe for human use. To ensure products are free from microbial contamination, multiple filtration steps are implemented across the biomanufacturing process.  The final sterilizing filtration pr...

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New insight into the genetics, developmental mechanism and therapeutic targets of Retinitis Pigmentosa NEW INSIGHT INTO THE GENETICS, DEVELOPMENTAL MECHANISM AND THERAPEUTIC TARGETS OF RETINITIS PIGMENTOSA

whitepaper

Nov 12, 2018

Hereditary degeneration of the human retina is genetically miscellaneous, with more than a hundred genes identified until now. Retinitis pigmentosa (RP) is a group of genetic retinal disorder which results in the degeneration of rods & cones photo-receptor. Retinitis pigmentosa is categorized by...

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Healthcare Artificial Intelligence Value Proposition HEALTHCARE ARTIFICIAL INTELLIGENCE VALUE PROPOSITION

whitepaper

Nov 12, 2018

According to the Wall Street Journal, deep learning systems have a fatal flaw: there is no way to tell how a decision was made. CytoSavvy is a pathology informatics software company using artificial intelligence to attack the big data problem for drug discovery and personalized medicine with a novel...

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Pharmaceutical Assay and Multicomponent Analysis using the LAMBDA 365 UV/Vis Spectrophotometer PHARMACEUTICAL ASSAY AND MULTICOMPONENT ANALYSIS USING THE LAMBDA 365 UV/VIS SPECTROPHOTOMETER

whitepaper

Nov 12, 2018

Combination drugs containing Paracetamol and Aspirin are widely used analgesics with anti-inflammatory properties for treatment of migraines. This application describes the efficient use of a UV/Vis instrument in determining the quantity of percent assay of Paracetamol according to U.S. Pharmacopeia...

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Artificial Intelligence in Healthcare ARTIFICIAL INTELLIGENCE IN HEALTHCARE

whitepaper

Nov 12, 2018

Since the inception of electronic health record (EHR) systems, volumes of patient data have been collected, creating an atmosphere suitable for translating data into actionable intelligence. The growing field of artificial intelligence (AI) has created new technology that can tackle large data sets,...

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Lean Manufacturing ofPolyurethane, Assisted by Near-infrared (NIR) andRaman Spectroscopy LEAN MANUFACTURING OFPOLYURETHANE, ASSISTED BY NEAR-INFRARED (NIR) ANDRAMAN SPECTROSCOPY

whitepaper

Nov 11, 2018

Chemical manufacturing such as polyurethane production is characterized by a cost-intensive production process combined with a negative ecological impact. These adverse effects can be significantly improved by using vibrational spectroscopy. This analytical technique can assist the operator of the p...

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Medication Reconciliation: The Biggest Patient Safety Issue Facing Clinicians Today MEDICATION RECONCILIATION: THE BIGGEST PATIENT SAFETY ISSUE FACING CLINICIANS TODAY

whitepaper

Nov 11, 2018

Executive Summary: Medication reconciliation is one of the most significant challenges facing healthcare organizations today. An inaccurate medication history can follow a patient throughout every encounter during a hospital stay and beyond. Even small errors can negatively affect outcomes, greatly ...

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Mortality Data in Healthcare Analytics MORTALITY DATA IN HEALTHCARE ANALYTICS

whitepaper

Nov 11, 2018

The incorporation of mortality data into healthcare data sets allows fraud prevention, accurate billing, and benefits distribution, and true outcome analysis (especially in fatal disease areas like oncology, where survival is a key endpoint). The net effect of adding mortality data is strengthening ...

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The Future of Electronic Health Records THE FUTURE OF ELECTRONIC HEALTH RECORDS

whitepaper

Nov 10, 2018

Ten years ago, one doctor in 10 kept digital records on their patients. The other 90 percent made notes on paper and stored them in manila folders on shelves and in filing cabinets. Paper records had some obvious disadvantages. They took up space, they were difficult to share with other physicians, ...

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CLONE CLONE

whitepaper

Nov 09, 2018

Blockchain is one of the most transformative technologies in recent history, a platform not only for distributed hosting and code execution, but also for a more equitable future. He has conceived a whole class of chimerical thinkers who are convinced that the future cryptographically assured will be...

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How to Achieve Sub-Second Substructure Query Response Times HOW TO ACHIEVE SUB-SECOND SUBSTRUCTURE QUERY RESPONSE TIMES

whitepaper

Nov 06, 2018

Chemical substructure and similarity searching is the cornerstone of most cheminformatics systems and a critical feature in electronic lab notebooks. As the scale of cheminformatics systems has grown, users are often frustrated with the performance of their chemical queries.

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An Editorial Mission: CRISPR Targets Animal Models AN EDITORIAL MISSION: CRISPR TARGETS ANIMAL MODELS

whitepaper

Nov 06, 2018

CRISPR genome-editing technology is only five years old, but it has already made remarkable strides in biomedical, microbial, and agricultural research. CRISPR affords scientists the ability to edit multiple genes at once in any extant organism, which is especially relevant for generating in vivo mo...

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HEALTHCARE’S NEW INNOVATION AGENDA HEALTHCARE’S NEW INNOVATION AGENDA

whitepaper

Nov 05, 2018

Anecdotal evidence abounds: Healthcare systems report deploying artificial intelligence (AI) and machine learning tools to support clinical decision-making. Big Data and genomics have accelerated the arrival of precision medicine. And recruits from Silicon Valley, filling positions that never before...

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Solid Lipid NanoParticles SOLID LIPID NANOPARTICLES

whitepaper

Oct 26, 2018

Formulators of active pharmaceutical ingredients (APIs) often try to find ways to prevent aerial oxidation, mask an unpleasant taste, increase bioavailability, or control the way an API is delivered (to target a particular cell, tissue, or organ, for example).

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An Introduction to CAR T-Cell Production AN INTRODUCTION TO CAR T-CELL PRODUCTION

whitepaper

Oct 23, 2018

Immunotherapy harnesses the components of an individual's own immune system to identify and attack cancer cells. One form of immunotherapy is adoptive cell transfer (ACT), where the patient's immune cells are collected, genetically modified, and re-infused. CAR-T immunotherapy is one type of...

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Better Heart Health Whitepaper BETTER HEART HEALTH WHITEPAPER

whitepaper

Oct 22, 2018

In recognition of World Heart Day, September 29, 2018, Informa Pharma Intelligence would like to invite you to download our latest whitepaper, Better Heart Health with Mobile Apps? The Impact of Mobile Apps on Coronary Heart Disease in the US. This exploration into the results of a recent analysis o...

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Rheumatoid Arthritis - Old and New Approaches Shifting the Treatment Paradigm RHEUMATOID ARTHRITIS - OLD AND NEW APPROACHES SHIFTING THE TREATMENT PARADIGM

whitepaper

Oct 19, 2018

Download your copy of Rheumatoid Arthritis: Old and New Approaches Shifting the Treatment Paradigm. Access the contents of this essential whitepaper from Informa Pharma Intelligence and explore the current and future outlook for rheumatoid arthritis (RA) treatments. Such treatments remain ineffectiv...

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Miniaturisation of an HTRF methyltransferase assay that detects histone modifying activity MINIATURISATION OF AN HTRF METHYLTRANSFERASE ASSAY THAT DETECTS HISTONE MODIFYING ACTIVITY

whitepaper

Oct 19, 2018

High throughput screening is mostly done in pharmaceutical companies that test whole libraries of compounds. Reducing the assay volume will reduce operating costs. At the same time, it is necessary to prove that the smaller volume will not have a negative impact on assay sensitivity and reliability....

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THE BUSINESS VALUE OF IMPROVING PATIENT EXPERIENCE THE BUSINESS VALUE OF IMPROVING PATIENT EXPERIENCE

whitepaper

Oct 18, 2018

With the healthcare industry bowing to consumerization, consumers are expecting and demanding higher quality service from their providers. Retaining patients, particularly in the current age of healthcare consumerization, is becoming more difficult. As such, healthcare organizations must take proact...

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CropLife International Position on Fall Armyworm CROPLIFE INTERNATIONAL POSITION ON FALL ARMYWORM

whitepaper

Oct 16, 2018

Fall Armyworm (FAW) is a destructive pest native to the tropical and subtropical regions of the Americas, having been found everywhere from South America to eastern and central North America. FAW targets more than 80 different plants including rice, cotton, wheat and soybeans, it has been particular...

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Measuring the Impact of Pharmacy Customer Loyalty on Health System Utilization and Readmission Rates MEASURING THE IMPACT OF PHARMACY CUSTOMER LOYALTY ON HEALTH SYSTEM UTILIZATION AND READMISSION RATES

whitepaper

Oct 15, 2018

Quantifying the direct and indirect value that a business unit delivers to its parent health system has traditionally been difficult. In this case study, we discuss the impact of pharmacy customer loyalty on the Fairview Health Services system and we introduce a new, data-driven methodology for meas...

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Roquette is Leading the Way in Biologic Drug Formulations ROQUETTE IS LEADING THE WAY IN BIOLOGIC DRUG FORMULATIONS

whitepaper

Oct 15, 2018

Molecular inclusion complexes using cyclodextrins have become a standard formulation strategy to improve the solubility or stability of active ingredients. Roquette has pioneered the development of betacyclodextrin technology, developing a full range of KLEPTOSE® betacyclodextrins

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Patheon’s Solid and Sterile Dosage Forms Brochure PATHEON’S SOLID AND STERILE DOSAGE FORMS BROCHURE

whitepaper

Oct 15, 2018

By partnering with Patheon, you have access to a remarkable range of dosage form technologies for oral solids. Take advantage of our expansive scientific resources and expertise to create a product that stands out in the marketplace. For more information about specific dosage forms, as well as where...

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The growing role of human factors and usability engineering for medical devices THE GROWING ROLE OF HUMAN FACTORS AND USABILITY ENGINEERING FOR MEDICAL DEVICES

whitepaper

Oct 13, 2018

Medical errors have been cited as the cause of nearly 100,000 deaths per year in the US healthcare system by the US Institute of Medicine in 1994 in its book, To err is human: Building a safer health system. According to the World Health Organization’s website, similar trends exist for Europea...

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Bacteriophages and their applications BACTERIOPHAGES AND THEIR APPLICATIONS

whitepaper

Oct 10, 2018

Bacteriophages are ubiquitous in our world, mainly in the oceans, soil, the water and food we consume. They can be used efficiently in modern biotechnology, as well as alternatives to antibiotics for many antibiotic-resistant bacterial strains.

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THE ADVANTAGE OF HOLLOW FIBER BIOREACTORS THE ADVANTAGE OF HOLLOW FIBER BIOREACTORS

whitepaper

Oct 09, 2018

It is now appreciated that conventional cell culture techniques are not the most physiologically relevant way to grow cells or the optimal way to harvest biologics for production. Cells grown on nonporous plastic dishes suffer from uneven nutrient distribution and constant disruption during passagin...

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A Case for Online Water Bioburden Analyzers A CASE FOR ONLINE WATER BIOBURDEN ANALYZERS

whitepaper

Oct 06, 2018

An industry workgroup has identified the benefits of a new class of instrumentation for real-time water bioburden analysis, noting its “potential to improve pharmaceutical water system operations, reduce costs, and ensure water quality.” The instrumentation complements existing methods a...

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The interoperability opportunity: Improving healthcare with an end-to-end enterprise strategy THE INTEROPERABILITY OPPORTUNITY: IMPROVING HEALTHCARE WITH AN END-TO-END ENTERPRISE STRATEGY

whitepaper

Oct 04, 2018

Picture a single patient in a single ICU anywhere in this country. Ten devices are connected to that single patient, and each device is producing data every few seconds or minutes. What can this one patient and the data he or she generates tell us about the interoperability opportunity we have ...

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The Patient Engagement Dilemma THE PATIENT ENGAGEMENT DILEMMA

whitepaper

Oct 04, 2018

In an effort to reduce costs and improve patient clinical outcomes, the Affordable Care Act (ACA) in the US has been instrumental in driving widespread changes in the healthcare delivery system. These changes have caused a cultural shift in the way in which clinicians and patients interact and ...

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Driving Sales Behavior With Non-Cash Rewards DRIVING SALES BEHAVIOR WITH NON-CASH REWARDS

whitepaper

Oct 03, 2018

In the end, you need to be rewarding your sales reps with more than just money if you want to keep them motivated and if you want your sales compensation plan to deliver on its promises.

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Change the sales rep experience, improve the customer experience CHANGE THE SALES REP EXPERIENCE, IMPROVE THE CUSTOMER EXPERIENCE

whitepaper

Oct 03, 2018

The first CRM launch truly changed the way sales were managed. We went from tracking customers on spreadsheets (and even in rolodexes) to tracking them and their attendant opportunities with software. It wasn’t long before reps started to feel the purpose of a CRM was more about preserving the...

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Pipeline Management and Forecasting Are Key to Improving the Sales Experience PIPELINE MANAGEMENT AND FORECASTING ARE KEY TO IMPROVING THE SALES EXPERIENCE

whitepaper

Oct 03, 2018

Let’s explore some of the current processes around pipeline management and forecasting and how they can be improved.

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Cancer Cell Culture CANCER CELL CULTURE

whitepaper

Oct 02, 2018

Cell culture is practiced extensively throughout the world today. The techniques required to allow cells to grow and be maintained outside the body have been developed throughout the 20th century. In the 50 years since the publication of the first human cancer cell line, HeLa (1), thousands of ...

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Site Directed Nucleases (SDN) for targeted genome modification SITE DIRECTED NUCLEASES (SDN) FOR TARGETED GENOME MODIFICATION

whitepaper

Oct 02, 2018

Crop improvement through breeding crosses uses genetic variation to create new combinations of characteristics. The development of a new plant variety through conventional breeding requires consecutive rounds of crossing and selection that integrates existing and new genetic variation to yield a pla...

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Communicating the bio-based content of products in the EU and the US COMMUNICATING THE BIO-BASED CONTENT OF PRODUCTS IN THE EU AND THE US

whitepaper

Oct 02, 2018

Bio-based products from forestry and agriculture have a long history of application, such as paper, board and various chemicals and materials. The last decades have seen the emergence of new bio-based products in the market. Some of the reasons for the increased interest lie in the bio-based product...

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5 ways Artificial Intelligence is transforming healthcare operations 5 WAYS ARTIFICIAL INTELLIGENCE IS TRANSFORMING HEALTHCARE OPERATIONS

whitepaper

Sep 28, 2018

While the practical applications of artificial intelligence (AI) are still being discovered, one area of AI natural language processing (NLP) is already helping advance the revenue cycle. Discover how the right NLP can support accuracy, efficiency and revenue integrity by powering comprehensive clin...

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The Evolution Of Anti-Body-Drug Manufacturing THE EVOLUTION OF ANTI-BODY-DRUG MANUFACTURING

whitepaper

Sep 26, 2018

Even before the 1980s, the notion of attaching a cytotoxic agent to a tumor-specific antibody captured the collective imagination of the international drug development community. Were antibody-drug conjugates (ADCs) the magic bullets everyone was looking for that could, among other things, cure canc...

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First Things First: Primary Cells in Research FIRST THINGS FIRST: PRIMARY CELLS IN RESEARCH

whitepaper

Sep 25, 2018

Primary cells are collected directly from living tissues, and as such, more closely resemble in vivo cells from a genetic and physiological perspective. This feature makes primary cells a treasure trove of potential for investigating in vivo mechanisms, responses, and pathologies. To use primary cel...

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Cybersecurity of medical devices CYBERSECURITY OF MEDICAL DEVICES

whitepaper

Sep 25, 2018

Increasing the connectivity of medical devices to computer networks and the convergence of technologies has exposed vulnerable devices and software applications to incidents. The need to protect patient data from cyber-attack is now well understood. However, the potential impact on clinical care and...

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Improved Nucleic Acid QC with Parallel CE IMPROVED NUCLEIC ACID QC WITH PARALLEL CE

whitepaper

Sep 21, 2018

Nucleic acid quality assessment is a crucial step to the success or failure of DNA and RNA-based workflows. New methods and quality standards continually develop along with new applications. Whether for new sequencing chemistry, PCR strategy, or type of gene editing, understanding sample quality is ...

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Detection of immune checkpoint markers in peripheral blood mononuclear cell lysates with AlphaLISA DETECTION OF IMMUNE CHECKPOINT MARKERS IN PERIPHERAL BLOOD MONONUCLEAR CELL LYSATES WITH ALPHALISA

whitepaper

Sep 19, 2018

Peripheral blood mononuclear cells (PBMCs) are a heterogeneous the population of blood cells having round nuclei. They consist of monocytes, macrophages, dendritic cells and lymphocytes (T cells, B cells, and NK cells). In order to induce and upregulate the expression of specific immune checkpoint m...

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Single-Cell Multi-omics to Detect Gene Expression SINGLE-CELL MULTI-OMICS TO DETECT GENE EXPRESSION

whitepaper

Sep 19, 2018

Quantifying single-cell gene expression at the mRNA and protein level has the potential to reveal novel mechanisms of gene regulation and cell types that have been previously unappreciated in immunology. A new multi-omics technique, BD AbSeq, allows the analysis of both the transcriptome and proteom...

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Enabling Data Integrity from Drug Discovery through Manufacturing ENABLING DATA INTEGRITY FROM DRUG DISCOVERY THROUGH MANUFACTURING

whitepaper

Sep 19, 2018

When discussing the success of a drug therapy, a common topic amongst biopharmaceutical companies is data quality and data integrity; what the challenges are and what the key elements are to ensuring that the latest discovery is patentable, does not result in re-conducting critical research or devel...

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Healthcare reimagined HEALTHCARE REIMAGINED

whitepaper

Sep 17, 2018

Regulatory requirements, fierce competition, and rapidly emerging technologies are creating new complexities for those operating in the healthcare sector. Many are working out how to deliver better health outcomes whilst managing evolving consumer needs, behaviors, and treatments, along with the sig...

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How Beacon Health System Gained Competitive Advantage and Acquired New Patients through Telehealth HOW BEACON HEALTH SYSTEM GAINED COMPETITIVE ADVANTAGE AND ACQUIRED NEW PATIENTS THROUGH TELEHEALTH

whitepaper

Sep 15, 2018

Beacon Health System, the nonprofit parent organization of Elkhart General Hospital and Memorial Hospital of South Bend that provides care throughout Indiana and Michigan, was in search of a convenient care delivery service that could be integrated across its system. Through this service, Beacon hop...

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Promoting Health, Preventing Disease PROMOTING HEALTH, PREVENTING DISEASE

whitepaper

Sep 12, 2018

The European Observatory on Health Systems and Policies supports and promotes evidence-based health policy-making through comprehensive and rigorous analysis of health systems in Europe. It brings together a wide range of policy-makers, academics, and practitioners to analyze trends in health reform...

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Unchained High Throughput Automated PH-Measurements UNCHAINED HIGH THROUGHPUT AUTOMATED PH-MEASUREMENTS

whitepaper

Sep 07, 2018

One of the major challenges in biologic drug development is the need to characterize formulations of drug candidates. One significant bottleneck in this process is pH measurement of formulations. Measuring pH is ubiquitous in the laboratory and critical for preparing buffers, analyzing formulations,...

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Biotechnology Resources on the Internet 2019 BIOTECHNOLOGY RESOURCES ON THE INTERNET 2019

whitepaper

Sep 01, 2018

Food is not only a central part of our daily lives; how food is produced, distributed and consumed is also at the centre of important nutrition, environmental and social challenges the world faces today. Our food system is under stress and in need of profound transformation if it is to provide the b...

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Top Five Asian Cancers – Trends in Clinical Development TOP FIVE ASIAN CANCERS – TRENDS IN CLINICAL DEVELOPMENT

whitepaper

Sep 01, 2018

This important white paper provides an in-depth analysis of the clinical trial landscape in 10 Asian countries related to effective therapies of treatment of the five most prevalent and life-threatening Asian cancers.

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Epidiolex and Epilepsy - big changes for medical marijuana EPIDIOLEX AND EPILEPSY - BIG CHANGES FOR MEDICAL MARIJUANA

whitepaper

Aug 28, 2018

With the FDA’s landmark approval of Epidiolex, a cannabidiol used to treat rare, severe pediatric epilepsies, the only obstacle to the legal sale of the drug is DEA reclassification of cannabidiol (CBD). With reclassification likely in the next 90 days, what does it mean for the epilepsy marke...

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The Evolution Of Biopharmaceutical Facility Designs THE EVOLUTION OF BIOPHARMACEUTICAL FACILITY DESIGNS

whitepaper

Aug 22, 2018

In the lifecycle of pharmaceutical and biopharmaceutical commercial manufacturing, the one constant has been changed. With the advent of modern therapeutics, large-scale commercial manufacturing became commonplace. And typically such manufacturing produced large-scale purpose-built facilities design...

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Perspectives and Good Practices for AI and Continuously Learning Systems in Healthcare PERSPECTIVES AND GOOD PRACTICES FOR AI AND CONTINUOUSLY LEARNING SYSTEMS IN HEALTHCARE

whitepaper

Aug 20, 2018

In the past few years, there has been a significant increase in the amount of information in healthcare, and this trend is accelerating. In addition to traditional data, such as those collected by in-vitro laboratory tests, imaging devices, physiological tests, and electronic health records, there a...

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IMMUNO-ONCOLOGY AND THE TUMOR MICROENVIRONMENT IMMUNO-ONCOLOGY AND THE TUMOR MICROENVIRONMENT

whitepaper

Aug 20, 2018

The development of cutting edge cancer treatment that uses the immune system is hinged on a better understanding of the tumor microenvironment (TME). The TME provides valuable context for understanding what subtypes of immune cells are present and how to exploit their position and ultimately destroy...

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Changing the future of data CHANGING THE FUTURE OF DATA

whitepaper

Aug 17, 2018

With fewer successful drug launches in the market and expiring patents, competitive intelligence, and commercial R&D decision makers are hard-pressed to make sound forecasting and planning decisions based on highly reliable data analysis. That’s a big challenge because, even with access to...

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Backup and Disaster Recovery as a Service: Driving New Data Protection Opportunities for Healthcare Organizations BACKUP AND DISASTER RECOVERY AS A SERVICE: DRIVING NEW DATA PROTECTION OPPORTUNITIES FOR HEALTHCARE ORGANIZATIONS

whitepaper

Aug 15, 2018

The data protection market is highly dynamic, driven by new application workload deployments and cloud capabilities. Healthcare organizations are embracing cloud computing and are more willing to move certain workloads, such as IT operations, to the cloud. Healthcare IT executives acknowledge that m...

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THE FUTURE OF TECHNOLOGY IN HEALTH AND HEALTH CARE THE FUTURE OF TECHNOLOGY IN HEALTH AND HEALTH CARE

whitepaper

Aug 12, 2018

Over the course of the last century, the medical sciences have made remarkable strides in developing safer and more effective treatments, such as minimally invasive surgery and new drugs that can help mitigate the effects of diseases such as arthritis. While the science of medicine has advanced, the...

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Measuring the concentration of Adeno-Associated Virus with multi-angle dynamic light scattering (MADLS) MEASURING THE CONCENTRATION OF ADENO-ASSOCIATED VIRUS WITH MULTI-ANGLE DYNAMIC LIGHT SCATTERING (MADLS)

whitepaper

Aug 11, 2018

For virus development and production, it is important to know the virus concentration at different stages of the process, to optimize the clone used as well as the production yields. For example, instances such as clone screening, multiplicity of infection (MOI) optimization and adaptations of cell ...

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Measuring the concentration of Adeno-Associated Virus with multi-angle dynamic light scattering (MADLS) MEASURING THE CONCENTRATION OF ADENO-ASSOCIATED VIRUS WITH MULTI-ANGLE DYNAMIC LIGHT SCATTERING (MADLS)

whitepaper

Aug 11, 2018

For virus development and production, it is important to know the virus concentration at different stages of the process, to optimize the clone used as well as the production yields. For example, instances such as clone screening, multiplicity of infection (MOI) optimization and adaptations of cell ...

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Theory of XRF, getting acquainted with the principles THEORY OF XRF, GETTING ACQUAINTED WITH THE PRINCIPLES

whitepaper

Aug 11, 2018

This booklet gives a general introduction to X-ray fluorescence (XRF) spectrometry and XRF analysis. It explains simply how a spectrometer works and how XRF analysis is done. It is intended for people new to the field of XRF analysis. Difficult mathematical equations are avoided and the booklet requ...

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Platform approach to purification of bacterial capsular polysaccharides for vaccine production PLATFORM APPROACH TO PURIFICATION OF BACTERIAL CAPSULAR POLYSACCHARIDES FOR VACCINE PRODUCTION

whitepaper

Aug 03, 2018

Capsular polysaccharides (CPS) of encapsulated bacterial pathogens can give rise to an effective immune response in humans and are commonly used in vaccine production. This whitepaper offers an overview of modern tools and technologies that can facilitate CPS based vaccine production. An alternative...

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Advantages of nanopore sequencing in microbiome research ADVANTAGES OF NANOPORE SEQUENCING IN MICROBIOME RESEARCH

whitepaper

Aug 02, 2018

The study of microbiomes the genetic material of all microorganisms in a given sample has recently attracted considerable attention, mainly due to the realization that the microbial composition of our bodies and environment can have a profound effect on our health. The composition of the human micro...

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Genomics: Consumerism, Commercialization and Health Care GENOMICS: CONSUMERISM, COMMERCIALIZATION AND HEALTH CARE

whitepaper

Aug 01, 2018

To address the issues and potential of genomics in health care, the Center for Connected Medicine tapped a range of experts for insights on the opportunities, challenges, excitement, and concern surrounding genomics, as featured in this whitepaper.

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Live-Cell Analysis of Cell Subsets and Heterogeneity LIVE-CELL ANALYSIS OF CELL SUBSETS AND HETEROGENEITY

whitepaper

Jul 30, 2018

Considerable heterogeneity exists in the properties and activity of individual cells, even in the simplest cell system. Analysis at the cell-by-cell level promises valuable and additional biological insight beyond which whole population measures may deliver. In this article, we consider this opportu...

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A buyer A BUYER'S GUIDE TO PROTEIN STABILITY MEASUREMENT PLATFORMS

whitepaper

Jul 26, 2018

Most biotherapeutics are proteins or protein derivatives, and the single biggest class of biopharmaceuticals currently on the market or in development are monoclonal antibodies (mAbs). The specific binding nature of antibodies has provided the opportunity for the biopharmaceutical industry to use th...

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Incentive Compensation Management: Build Versus Buy INCENTIVE COMPENSATION MANAGEMENT: BUILD VERSUS BUY

whitepaper

Jul 23, 2018

Custom ICM solutions are built for you, not auditors, so they typically don’t offer visibility into actions performed over time. Auditors may lack confidence in your homegrown system, especially if they find errors or omissions. In fact, audit risk from errors and overpayments is often the mos...

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The Three “S’s” of a Great Incentive Compensation Management System THE THREE “S’S” OF A GREAT INCENTIVE COMPENSATION MANAGEMENT SYSTEM

whitepaper

Jul 23, 2018

It all ties together. You want your sales reps to behave a certain way and close a certain amount of deals in specific verticals that match your company’s 3- and/or 5-year vision, but the systems you currently have in place to drive this behavior are not working for any number of reasons. Most...

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Why Enterprise CPQ Implementations Fail WHY ENTERPRISE CPQ IMPLEMENTATIONS FAIL

whitepaper

Jul 23, 2018

You’ve reached a certain point in the evolution of your company and you know it’s time to invest in a CPQ system. But buyer beware: There’s a certain misconception around CPQ systems as being plug-in devices or turnkey-ready overlays of your existing infrastructure, or a simple app...

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Moving Away from Spreadsheets: How to Know When It’s Time MOVING AWAY FROM SPREADSHEETS: HOW TO KNOW WHEN IT’S TIME

whitepaper

Jul 23, 2018

The spreadsheet conundrum... Joe Smith, sales director for Great Start-Up Number 5 Billion and Thirty-One, puts on a blindfold and reaches out blindly for something, ANYTHING, to help him organize his team’s deals and commissions. He’s hopeful. He’s waiting. He knows he’ll co...

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Polyvinyl alcohol: Revival of a long lost polymer POLYVINYL ALCOHOL: REVIVAL OF A LONG LOST POLYMER

whitepaper

Jul 23, 2018

With target-oriented drug discovery and an increasing focus on specialized medicines, the manufacturing of final drug products is becoming more and more complex. The processing and formulation of active pharmaceutical ingredients (APIs) designed with a specific target and functionality in mind ...

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Disease Diagnosis in Smart Healthcare DISEASE DIAGNOSIS IN SMART HEALTHCARE

whitepaper

Jul 22, 2018

To promote sustainable development, the smart city implies a global vision that merges artificial intelligence, big data, decision making, information and communication technology (ICT), and the internet-of-things (IoT). The aging issue is an aspect that researchers, companies, and the governme...

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ATPlite assay performance in human primary cells ATPLITE ASSAY PERFORMANCE IN HUMAN PRIMARY CELLS

whitepaper

Jul 18, 2018

One of the criteria for a compound to be considered druggable is the ability to cause or block a biological activity without toxic effects in an in vitro setting using primary human cells. As a read-out for compound-induced activity or toxicity, it is common to determine cell proliferation or cell d...

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The Medical Costs of Childhood Injuries: Hospitalizations THE MEDICAL COSTS OF CHILDHOOD INJURIES: HOSPITALIZATIONS

whitepaper

Jul 15, 2018

In 2017, the total medical costs of injury-related hospitalizations of children age 19 and younger were $6.6 billion. This infographic breaks out the medical cost of hospitalizations of children by injury topic.

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NEW BIOTECHNOLOGY NEW BIOTECHNOLOGY

whitepaper

Jul 13, 2018

New Biotechnology is the official journal of the European Federation o Biotechnology (EFB) and is published bimonthly. It covers both the science of biotechnology and its surrounding political, business and financial milieu. The journal publishes peer-reviewed basic research papers, authoritative re...

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Mass Spectrometry For Advanced Proteomics: A Revolution In Biological Research MASS SPECTROMETRY FOR ADVANCED PROTEOMICS: A REVOLUTION IN BIOLOGICAL RESEARCH

whitepaper

Jul 11, 2018

Moving beyond its roots of merely sequencing the peptides of proteins, modern proteomics uses advanced technology to understand how structure, conformation, and post-translational modifications influence the protein's role within biological systems. Thanks to advancements in mass spectrometry an...

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The C-Suite battle plan for cyber security attacks in healthcare THE C-SUITE BATTLE PLAN FOR CYBER SECURITY ATTACKS IN HEALTHCARE

whitepaper

Jul 08, 2018

Cybersecurity is an evolving battlefield confronting the healthcare industry with unprecedented threats. Learn how to out-maneuver your opponents and secure your healthcare facility by employing astute military-inspired strategies and cutting-edge technologies.

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Healthcare commerce as a user-friendly experience HEALTHCARE COMMERCE AS A USER-FRIENDLY EXPERIENCE

whitepaper

Jul 07, 2018

Digitization is the absolute future of healthcare commerce so, why do only four percent of healthcare executives and leaders state they prefer automated payment plans? Outlined in this white paper, readers will learn how healthcare commerce can transcend the age of paper-based billing by understandi...

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Digital maturity inan age of digital excitement DIGITAL MATURITY INAN AGE OF DIGITAL EXCITEMENT

whitepaper

Jul 05, 2018

It is obvious that digital technologies hold the promise of solving many besetting healthcare problems. Yet if we are too positive, we run the risk of being uncritical and perhaps exploited by unscrupulous marketing, or even marketing equally caught up in the uncritical excitement. How, then, do we ...

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THE HEALTHCARE EXECUTIVE’S GUIDE THE HEALTHCARE EXECUTIVE’S GUIDE

whitepaper

Jul 04, 2018

Managing the complex financial aspects of your healthcare business is a daunting task. You need a holistic, intuitive and intelligent solution that empowers you to be proactive and control costs with precision. Use this guide to make the most informed decision when selecting an ERP solution where be...

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From plan to impact FROM PLAN TO IMPACT

whitepaper

Jul 04, 2018

Every three seconds someone in the world develops dementia. Dementia affects 50 million people, costing the global economy over US$1 trillion in 2018. By 2030, there will be an estimated 82 million people with dementia, placing an unprecedented strain on health systems around the world.

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Rise in Targeted Therapies Drives Needs for Small Volume Manufacturing RISE IN TARGETED THERAPIES DRIVES NEEDS FOR SMALL VOLUME MANUFACTURING

whitepaper

Jul 01, 2018

Biologics have experienced steady double-digit growth over the last 15 years and now comprise slightly more than a quarter of all New Molecular Entity (NME) FDA approvals. Similarly, EvaluatePharma's 2017 report on orphan drugs projects that by 2020, six of the 10 best-selling global drug therap...

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Recent developments in synthetic biology and metabolic engineering in microalgae towards biofuel production RECENT DEVELOPMENTS IN SYNTHETIC BIOLOGY AND METABOLIC ENGINEERING IN MICROALGAE TOWARDS BIOFUEL PRODUCTION

whitepaper

Jun 30, 2018

In the wake of the uprising global energy crisis, microalgae have emerged as an alternate feedstock for biofuel production. In addition, microalgae bear immense potential as bio-cell factories in terms of producing key chemicals, recombinant proteins, enzymes, lipid, hydrogen and alcohol. Abstractio...

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Opposites attract Blurring the lines between small and large molecule manufacturing OPPOSITES ATTRACT BLURRING THE LINES BETWEEN SMALL AND LARGE MOLECULE MANUFACTURING

whitepaper

Jun 28, 2018

The biopharmaceutical industry has grown impressively in recent years, with its global compound growth rate (CAGR) estimated to reach 8.5% between 2018-2023, outstripping traditional New Chemical Entity sectors1 . Emerging novel drugs show huge therapeutic potential, such as antibodydrug conjugates ...

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Microplastics: from Beach to Bench MICROPLASTICS: FROM BEACH TO BENCH

whitepaper

Jun 21, 2018

As plastics continue to enter the environment, understanding their global impact is vital to addressing microplastic pollution. Since its emergence as an environmental and potential human health threat, researchers have strived to develop tools for accurately measuring microplastics in environmental...

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Prostatype – White Paper PROSTATYPE – WHITE PAPER

whitepaper

Jun 20, 2018

Prostate Cancer is the most common type of cancer among men in Sweden as well as in many Western countries. However, approximately 85% of prostate cancer tumors are not rapidly progressing and will not cause clinical symptoms at the time of diagnosis, while the remaining 15% are more aggressive and ...

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The Latest Advances in Cell and Tissue Engrafted Mice THE LATEST ADVANCES IN CELL AND TISSUE ENGRAFTED MICE

whitepaper

Jun 19, 2018

Over the last century, the mouse has become the standard model organism of choice in academic laboratories and the pharmaceutical industry. The biological differences between mice and humans is a limiting factor in the translation of many discoveries to the clinical setting.

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WHAT HEALTHCARE ORGANIZATIONS SHOULD KNOW ABOUT THE GDPR WHAT HEALTHCARE ORGANIZATIONS SHOULD KNOW ABOUT THE GDPR

whitepaper

Jun 19, 2018

THE HEALTHCARE INDUSTRY IS FACING MULTIPLE CHALLENGES WHEN IT COMES TO PROTECTING SENSITIVE DATA. HERE’S AN OVERVIEW OF HOW THE RECENT EU GENERAL DATA PROTECTION REGULATIONS (GDPR) WILL AFFECT HEALTHCARE ORGANIZATIONS

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Healthcare Data Fuels Innovation in the Classroom HEALTHCARE DATA FUELS INNOVATION IN THE CLASSROOM

whitepaper

Jun 16, 2018

The current era of healthcare technology is marked by a need for problem solvers and professionals who can work with data and the information technology used to mine it. These skills are vital to successful innovation, requiring educators to present today’s student with new challenges in the c...

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BIOTECHNOLOGY UPDATE BIOTECHNOLOGY UPDATE

whitepaper

Jun 16, 2018

This Whitepaper provides up-to-date information on activities related to biotechnology at the Organisation for Economic Co-operation and Development (OECD). It is mainly intended for OECD staff and delegates to OECD meetings who are already familiar with certain aspects of the Organisation’s w...

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What to Look for in an Informatics Platform for Biologics R&D WHAT TO LOOK FOR IN AN INFORMATICS PLATFORM FOR BIOLOGICS R&D

whitepaper

Jun 15, 2018

In silico molecular biology tools, electronic lab notebooks, and systems for registration, sample management, workflow management, and request management form the foundation of informatics for biologics R&D. The informatics platform you adopt and develop over time is an important consideration w...

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Examples of Recently Tested Resins Suggest Wide Applicability of the Technology EXAMPLES OF RECENTLY TESTED RESINS SUGGEST WIDE APPLICABILITY OF THE TECHNOLOGY

whitepaper

Jun 14, 2018

Chromassette® is a modular chromatography technology that offers the separation capabilities of conventional chromatography plus the convenience, scalability and other benefits of a pre-packed cassette. Each Chromassette cassette is distinguished by a novel internal scaffold that provides consis...

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High-performance Rules Engine for Population Health Management HIGH-PERFORMANCE RULES ENGINE FOR POPULATION HEALTH MANAGEMENT

whitepaper

Jun 14, 2018

A business rules engine is a piece of software that manages the internal operation of a large software system based on predefined business logic. It is a specific collection of design-time and run-time software enabling an organization to define, analyze, execute, audit, and maintain a variety of bu...

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Resistance Development to Bacteriophages Occurring
during Bacteriophage Therapy RESISTANCE DEVELOPMENT TO BACTERIOPHAGES OCCURRING DURING BACTERIOPHAGE THERAPY

whitepaper

Jun 10, 2018

Bacteriophage (phage) therapy, i.e., the use of viruses that infect bacteria as antimicrobial agents, is a promising alternative to conventional antibiotics. Indeed, resistance to antibiotics has become a major public health problem after decades of extensive usage. However, one of the main question...

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Improving Water/Wastewater Infrastructure Performance with Operational Analytics IMPROVING WATER/WASTEWATER INFRASTRUCTURE PERFORMANCE WITH OPERATIONAL ANALYTICS

whitepaper

Jun 07, 2018

Operational analytics is rapidly emerging as an effective system for capturing and evaluating the high-impact, high-value data for better business outcomes. It helps infrastructure professionals to better design, operate, and maintain water and wastewater infrastructure at a level of excellence that...

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Getting to First-in-Human Clinical Trials: A Make-or-Break Milestone for Small Biopharmas GETTING TO FIRST-IN-HUMAN CLINICAL TRIALS: A MAKE-OR-BREAK MILESTONE FOR SMALL BIOPHARMAS

whitepaper

Jun 07, 2018

"Faster and better” has become the mantra for biopharmaceutical companies as they face intense pressure to get therapies to market faster. Quickly proving efficacy in first-in-human (FIH) trials is a make-or-break milestone for these cash-strapped companies whose hopes hinge upon one or t...

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Nanotechnology NANOTECHNOLOGY

whitepaper

Jun 06, 2018

Nanotechnology is now a mature subject in terms of the basic science, and while there were many claims for what it could achieve 20 years ago when the funding in the area was beginning to ramp up, there is now much more realism in most areas of application. The application to medicine and healthcare...

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Strategies for Enhanced Treasury Operations in Healthcare STRATEGIES FOR ENHANCED TREASURY OPERATIONS IN HEALTHCARE

whitepaper

Jun 05, 2018

Every hospital and health system has a portfolio of key financial resources such as cash, credit, leverage, and invested assets that its leaders seek to deploy in a manner that balances the pursuit of growth with the organization’s risk management and financial health objectives.

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Creating Harmonized Food Safety Processes Through Integration CREATING HARMONIZED FOOD SAFETY PROCESSES THROUGH INTEGRATION

whitepaper

Jun 05, 2018

The Food and Beverage industry is increasingly adapting to the Global Food Safety Initiative (GFSI) as its “stamp” of high quality and safety. In fact, many leading organizations today will only work with GFSI compliant suppliers. The GFSI-benchmarked food safety schemes SQF, BRC and IFS...

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Enhance Precision Oncology Trial Success ENHANCE PRECISION ONCOLOGY TRIAL SUCCESS

whitepaper

Jun 04, 2018

A convergence of biological data and computing power is yielding amazing technological progress in clinical research and development. Vast amounts of data, often from disparate sources, are enabling the transformation of treatment paradigms. In many therapeutic areas, with oncology chief among them,...

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Real-world evidence: Driving a new drug development paradigm in oncology REAL-WORLD EVIDENCE: DRIVING A NEW DRUG DEVELOPMENT PARADIGM IN ONCOLOGY

whitepaper

Jun 01, 2018

Evidence generation in oncology is at a key inflection point. Given the rapid pace of scientific innovation, historical approaches to drug development are increasingly burdensome, with randomized controlled trials remaining incredibly costly and time intensive to conduct, and having a low certainty ...

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Bioinformatics: Data Knowledge Management With Complex Datasets BIOINFORMATICS: DATA KNOWLEDGE MANAGEMENT WITH COMPLEX DATASETS

whitepaper

May 31, 2018

With the growth of biologics showing no signs of stopping, bioinformatics continues to be a key driver when it comes to R&D development. Laboratories and their data systems are now expected to handle and manage biotechnology’s densely structured proteins, with some antibodies standing at 2...

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Exploring the hallmarks of cancer with real-time live-cell analysis EXPLORING THE HALLMARKS OF CANCER WITH REAL-TIME LIVE-CELL ANALYSIS

whitepaper

May 31, 2018

Our understanding of cancer cell biology has progressed enormously since Hanahan and Weinberg published their landmark paper describing six hallmarks of cancer in 20001. Since this time, breakthroughs in areas such as immune modulation and the tumor microenvironment have led to these hallmarks being...

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Defending Against the Next Wave of Biosimilars DEFENDING AGAINST THE NEXT WAVE OF BIOSIMILARS

whitepaper

May 29, 2018

Biosimilar competition is disruptive and unpredictable: Not quite a true brand or a generic, it’s tough to predict what a biosimilar launch situation or go-to-market strategy will look like. We have examples to draw upon but no perfect analogues for each upcoming situation. It’s imperati...

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Outsourcing Trends in Pharma & Biotech OUTSOURCING TRENDS IN PHARMA & BIOTECH

whitepaper

May 29, 2018

Outsourcing has been labelled as one of this century’s “greatest organizational and industry structure shifts”.The general model in the pharmaceutical and biotechnology industries sees market authorization holders (MAH) rely on external partners to execute a range of activities inc...

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Long term live cell imaging in a high-content system LONG TERM LIVE CELL IMAGING IN A HIGH-CONTENT SYSTEM

whitepaper

May 29, 2018

Setting up live cell experiments can be challenging, as temperature, CO2, and evaporation need to be carefully controlled to ensure optimal cell growth conditions. In this technical note, we monitor evaporation rates, cell growth and morphology inside the temperature- and CO2-controlled live cell ch...

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Agile Process Development In Biopharmaceuticals AGILE PROCESS DEVELOPMENT IN BIOPHARMACEUTICALS

whitepaper

May 25, 2018

The development of novel therapeutic products involves a complex network of internal departments and external partners. Different groups across Process Development organizations typically use a variety of approaches to capture, manage, analyze and report data. These can range from paper and Excel to...

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Patient health records and confidentiality PATIENT HEALTH RECORDS AND CONFIDENTIALITY

whitepaper

May 25, 2018

Individuals have a right to access their own health records, and in limited circumstances, access to the records of other people. The Government has made a commitment that patients should gain access to their health records within 21 days following a request. Access to health records may also be gra...

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COLLABORATION IS KING: STRENGTHENING THE PAYER/PROVIDER RELATIONSHIP FOR VALUE-BASED SUCCESS COLLABORATION IS KING: STRENGTHENING THE PAYER/PROVIDER RELATIONSHIP FOR VALUE-BASED SUCCESS

whitepaper

May 25, 2018

And the move to value-based payment models is exactly that: a tremendous change that will transform the healthcare market—offering unparalleled opportunities for healthcare organizations to better manage costs while dramatically improving the health and well-being of patients. But this shift i...

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Biorobotics: an Instrument for an Improved Quality of Life. BIOROBOTICS: AN INSTRUMENT FOR AN IMPROVED QUALITY OF LIFE.

whitepaper

May 21, 2018

This paper deals with the developed researches of biorobotics, as an instrument for the maintenance of the quality of human senses, complete control of the nervous system, activation of neuron circuits, recovery of damaged neuromotor functions, rehabilitation of vocal chords, and neuromotor system c...

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A Healthcare Prescription for the GCC A HEALTHCARE PRESCRIPTION FOR THE GCC

whitepaper

May 18, 2018

The healthcare industry across the Gulf Cooperation Council (GCC) is in the midst of a transition, one that will help improve the operating environment, reduce costs and increase opportunities across the value chain of the multibillion-dollar industry.

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Trends in the Biosimilars Market TRENDS IN THE BIOSIMILARS MARKET

whitepaper

May 17, 2018

Despite biosimilars being available for over ten years in some markets, the biosimilars market continues to evolve. Development of biosimilars is a truly global endeavour, helped by the spread of regulatory guidance. In this white paper, we explore the biosimilar R&D landscape, physician attitud...

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Powerful Bioinformatic Support for Specialized Therapeutic Antibody Discovery POWERFUL BIOINFORMATIC SUPPORT FOR SPECIALIZED THERAPEUTIC ANTIBODY DISCOVERY

whitepaper

May 17, 2018

Achieving effective sequence analysis across biologic drug development their highly targeted specificity and efficacy in treating disease, monoclonal antibody (mAB) drugs have grown faster than any other class of therapeutic drugs in recent years. Accompanying this, a large body of work has focused ...

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Closing the gap in plant genomes CLOSING THE GAP IN PLANT GENOMES

whitepaper

May 14, 2018

According to the latest estimates, approximately 400,000 plant species are currently known to science; however, 21% of them are at risk of extinction due to factors such as climate change, habitat loss, and disease. Combatting these challenges is a key focus of plant research efforts, particularly i...

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BIOTECH PEANUT BIOTECH PEANUT

whitepaper

May 09, 2018

The peanut industry has attempted to use all available methods to reduce cost of production and improve quality of US peanuts. They have funded work on bioengineered peanuts since 1989 but at lower levels than other crops in the US. The industry is conducting a review of their position on this area ...

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A new vision for comprehensive care coordination A NEW VISION FOR COMPREHENSIVE CARE COORDINATION

whitepaper

May 05, 2018

Transitioning patients between outpatient, inpatient, post-acute and home settings can be a major challenge for hospitals. For organizations participating in value-based reimbursement models, it can also be costly. This case study examines how Holyoke (Mass.) Medical Center redesigned its care manag...

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HEALTHCARE IN SAUDI ARABIA HEALTHCARE IN SAUDI ARABIA

whitepaper

May 05, 2018

Investing in alternative real estate asset classes such as healthcare is a growing trend among global and local investors seeking diversification benefits as well as long term stability gave the defensive nature of the underlying income stream. In Saudi Arabia, rising demand for healthcare and gover...

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The barriers between us and better health THE BARRIERS BETWEEN US AND BETTER HEALTH

whitepaper

May 01, 2018

The term social determinants of health (SDoH) is often used to refer to any nonmedical factors influencing health, including health-related knowledge, attitudes, beliefs or behaviors (e.g. smoking); however, SDoH also include “upstream” factors, such as social disadvantage, risk exposure...

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The Present and Future State of Synthetic Biology in Canada THE PRESENT AND FUTURE STATE OF SYNTHETIC BIOLOGY IN CANADA

whitepaper

May 01, 2018

The synthetic biology community convened on March 6-7, 2018 at the “Canada Synbio 2018” Conference and Workshop as part of an ongoing effort to raise the profile and capacity of the synthetic biology community in Canada. The conference brought together a wide range of presenters and stak...

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ADDRESSING THE VALUE OF GENE THERAPY: ENHANCING PATIENT ACCESS TO TRANSFORMATIVE TREATMENTS ADDRESSING THE VALUE OF GENE THERAPY: ENHANCING PATIENT ACCESS TO TRANSFORMATIVE TREATMENTS

whitepaper

May 01, 2018

Gene therapy is a radical shift in our approach to disease treatment. By modifying the expression of a patient’s genes or repairing abnormal genes, gene therapy often addresses the root cause of diseases. While several new gene and cell therapies have received FDA approvals over the past 20 ye...

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Modularity for Maximum Mobility and Manipulation MODULARITY FOR MAXIMUM MOBILITY AND MANIPULATION

whitepaper

Apr 29, 2018

We present a set of modular series-elastic actuators (SEAs) that allow rapid and robust prototyping of mobile legged robots. The SEA modules were originally developed for a snake robot, SEA Snake, and have recently been reconfigured into Snake Monster, a multi-modal walking robot that can be easily ...

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Can Phage replace Chemicals in Post Harvest Poultry Processing? CAN PHAGE REPLACE CHEMICALS IN POST HARVEST POULTRY PROCESSING?

whitepaper

Apr 28, 2018

Salmonella continues to be a leading cause of foodborne illness despite significant resources of time money and effort put forth by industry to combat its presence. In addition, the pressure is mounting to reduce the use of harsh chemicals due to worker safety concerns.

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Pesticide Use on Cannabis PESTICIDE USE ON CANNABIS

whitepaper

Apr 28, 2018

Legalized cannabis production is a rapidly growing agricultural industry. However, given that cannabis production has developed and operated in an unregulated setting various practices have been adopted that are at odds with accepted regulations regarding human safety and environmental impacts. Chie...

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VISUALIZING APOPTOSIS AS IT HAPPENS VISUALIZING APOPTOSIS AS IT HAPPENS

whitepaper

Apr 27, 2018

Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Aberrations in this form of programmed cell death have been implicated in several pathological conditions including cancer, muscular atrophy, and autoimmune disease. The biochemical and morphological events ...

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Large insights into microorganisms LARGE INSIGHTS INTO MICROORGANISMS

whitepaper

Apr 27, 2018

Microorganisms are the most abundant and diverse forms of life on Earth, with an estimated 1 trillion species. They are essential components of all ecosystems and play a crucial role in health, disease and many industrial processes. The field of microbiology has seen the enormous impact of sequencin...

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Microbiological Safety Testing of Cannabis MICROBIOLOGICAL SAFETY TESTING OF CANNABIS

whitepaper

Apr 20, 2018

Cannabis is increasingly becoming legal at the state level in the U.S., for either medical or recreational use. Each of these states has had to wrestle with the question of how to ensure the safety of a new product that is not covered under any existing safety guidelines. Safety testing in other agr...

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Analysis of Microplastics using FTIR Imaging ANALYSIS OF MICROPLASTICS USING FTIR IMAGING

whitepaper

Apr 19, 2018

As plastics continue to enter the environment, understanding their global impact is vital to addressing microplastic pollution. Since its emergence as an environmental and potential human health threat, researchers have strived to develop tools for accurately measuring microplastics in environmental...

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Opening Doors to a Whole New View of Biology with Mass Spectrometry OPENING DOORS TO A WHOLE NEW VIEW OF BIOLOGY WITH MASS SPECTROMETRY

whitepaper

Apr 09, 2018

Liquid chromatography and mass spectrometry (LC-MS) have transformed the field of proteomics, enabling researchers to rapidly survey the contents of complex biological samples. However, until relatively recently it has proven challenging and labor-intensive to perform accurate comparisons across mul...

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AZ BioPac Powder Transfer: Getting Your Biologic to Market Faster AZ BIOPAC POWDER TRANSFER: GETTING YOUR BIOLOGIC TO MARKET FASTER

whitepaper

Apr 03, 2018

This white paper quantifies how one simple change can drastically reduce the time it takes to get biologics manufactured.Getting media and buffer into large-scale continuous bioprocessing has been burdensome, time-consuming and messy. Upgrading to modern, single-use powder handling in your process g...

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Microbiome Modulator Drugs – The New Generation of Therapeutic MICROBIOME MODULATOR DRUGS – THE NEW GENERATION OF THERAPEUTIC

whitepaper

Mar 29, 2018

Since the discovery of the microbiome, biomedical research has been highly focused on understanding how exactly its interactions within the body contribute to health and disease, and drug development companies are very interested in understanding the potential of microbiome modulating therapies.

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Unleash Your Biologic UNLEASH YOUR BIOLOGIC

whitepaper

Mar 28, 2018

For biopharmaceutical quantification, it is important that these often highly concentrated biologic drugs can be measured with high accuracy in a dilution-free and batch-wise manner. While most analysis methods don’t cover all of these aspects and tend to suffer from some inherent drawbacks su...

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The Next Era of Genomics and Healthcare THE NEXT ERA OF GENOMICS AND HEALTHCARE

whitepaper

Mar 25, 2018

The world of healthcare is changing. Two revolutionary technologies, genomics, and blockchain, are poised to significantly improve health and well-being across the globe. Genomic medicine can enhance the understanding and treatment of as many as 7,000 rare diseases, alongside cancers, complex and lo...

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Cultivation of cell aggregates CULTIVATION OF CELL AGGREGATES

whitepaper

Mar 24, 2018

For many applications like disease modeling, drug toxicity assessment, and manufacture of stem cell-based products, three-dimensional (3D) cell aggregates are of great interest.  Researchers at the Instituto de Biologia Experimental e Tecnológica (iBET) in Portugal have tested the suitab...

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A DIGITAL TIME-LAPSE BRIGHT FIELD TECHNOLOGY TO DRIVE FASTER, HIGHER THROUGHPUT BIOANALYSIS A DIGITAL TIME-LAPSE BRIGHT FIELD TECHNOLOGY TO DRIVE FASTER, HIGHER THROUGHPUT BIOANALYSIS

whitepaper

Mar 22, 2018

The constant need to develop more rapid and cost-effective technologies for accurate, sensitive and specific detection in biological samples is a driving force behind the integration of new sample preparation tools, automation, and informatics across the bioanalytical workflow. These technologies ha...

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2018 Life Sciences Trends 2018 LIFE SCIENCES TRENDS

whitepaper

Mar 21, 2018

Want to learn more about 2018 Life Sciences trends? Download the Industry Trends whitepaper to:Better understand the global trends impact the life sciences industry.Understand the compliance and technology trends that affect the industry.Gain valuable knowledge to enhance your goal-setting and strat...

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Is A Rapid Cooling Step Needed When Freezing Cells For Cryopreservation? IS A RAPID COOLING STEP NEEDED WHEN FREEZING CELLS FOR CRYOPRESERVATION?

whitepaper

Mar 14, 2018

Successful cell cryopreservation requires a controlled cooling rate. Cooling too rapidly or too slowly will lead to a poorer outcome. This is true because of the physical environment cells experience during cryopreservation. As ice forms in the extracellular solution, pure water is locked away like ...

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BIOTECHNOLOGY FOR CLEAN INDUSTRIAL PRODUCTS AND PROCESSES BIOTECHNOLOGY FOR CLEAN INDUSTRIAL PRODUCTS AND PROCESSES

whitepaper

Mar 11, 2018

The report fits well into the changing framework of the OECD’s overall programme of work, which gives high priority to environmental sustainability. The 1997 publication, Sustainable Development: OECD Policy Approaches for the 21st Century, testifies to the broad range of relevant OECD work in...

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Industrial Biotechnology and Biomass Utilization INDUSTRIAL BIOTECHNOLOGY AND BIOMASS UTILIZATION

whitepaper

Mar 11, 2018

The bio-based economy can be loosely defined as consisting of those sectors that derive a majority of their market value from biological processes and/or products derived from natural materials, as opposed to products and processes associated with non-renewable resources and/or purely chemical proce...

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Advantages of Raman Microscopy and Imaging in Pharmaceutical QC and R&D: an in-depth Review ADVANTAGES OF RAMAN MICROSCOPY AND IMAGING IN PHARMACEUTICAL QC AND R&D: AN IN-DEPTH REVIEW

whitepaper

Mar 09, 2018

This application note provides examples that thoroughly emphasize the benefits of Raman microscopy and imaging by the SENTERRA II when utilized in pharmaceutical applications. It offers an intuitive smooth workflow, comprehensive validation, research grade spectroscopic performance, compact size and...

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Aligning Needs & Skills for Profitable Healthcare Facilities ALIGNING NEEDS & SKILLS FOR PROFITABLE HEALTHCARE FACILITIES

whitepaper

Mar 07, 2018

Developing a new generation of workers well equipped to remake the business as new challenges arise is a huge fear of CEOs, reports industry media. It’s a very real challenge: By 2030, 10,000 people per day will reach the average retirement age of 65, says the Pew Research Center. But don&rsqu...

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Pharmaceutical & Biotechnology Perspectives in Liquid Process Analytics PHARMACEUTICAL & BIOTECHNOLOGY PERSPECTIVES IN LIQUID PROCESS ANALYTICS

whitepaper

Mar 05, 2018

Analytical measurements are going digital. The advantages offered by the latest, cutting-edge in-line sensors and transmitters, such as greater process quality and yield, reduced sensor maintenance, and simplified regulatory compliance, are hard to ignore. ISM, METTLER TOLEDOʼs digital sensor techno...

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Patient-Centered Healthcare via Patient Generated Health Data PATIENT-CENTERED HEALTHCARE VIA PATIENT GENERATED HEALTH DATA

whitepaper

Mar 04, 2018

Hospital and health system executives are developing and implementing new tactics to meet the healthcare industry’s core strategic need: a higher value of care at lower cost. This objective has been aided by advanced technological solutions in medical-grade  remote patient monitoring (RPM...

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A biotechnology company for truly personalized skincare by combining epigenetics and blockchain technology A BIOTECHNOLOGY COMPANY FOR TRULY PERSONALIZED SKINCARE BY COMBINING EPIGENETICS AND BLOCKCHAIN TECHNOLOGY

whitepaper

Mar 01, 2018

The global skincare market is broadly classified under several categories including facial cleansers, facial moisturizers, anti-aging products, and hand/body lotions. They aid in improving the skin quality by preventing wrinkles, rejuvenating cells, combating aging, brightening the skin, and protect...

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Genetically modified plants for food use and human health an update GENETICALLY MODIFIED PLANTS FOR FOOD USE AND HUMAN HEALTH AN UPDATE

whitepaper

Mar 01, 2018

The Society periodically issues updates on reports (recent examples include updates on bovine spongiform encephalopathies and stem cells) and the following update, which is based on research published in the last three years, specifically addresses human health aspects of genetically modified foods ...

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NTA: Environmental Impact of Nanoparticles NTA: ENVIRONMENTAL IMPACT OF NANOPARTICLES

whitepaper

Feb 22, 2018

Despite being a relatively new technique, NTA has been recognized as showing promise as an analytical method which could furnish not just information about nanoparticle size and, equally importantly, concentration but that it could do so in complex sample types of high polydispersity (Montes-Burgos ...

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How Pharma Copes with the Pain of Developing Abuse-Deterrent Opioids HOW PHARMA COPES WITH THE PAIN OF DEVELOPING ABUSE-DETERRENT OPIOIDS

whitepaper

Feb 21, 2018

With the wide availability of generic opioid analgesics, such as oxycodone and hydromorphone, the abuse of prescription opioids has become a major public health problem in the US. Consequently, in January 2013, the FDA released draft guidance for drug makers that mandates inclusion of abuse-deterren...

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Tale of Two Molecules TALE OF TWO MOLECULES

whitepaper

Feb 20, 2018

Two molecules, both designed to treat the same condition, both with solubility challenges. Two biopharma companies racing to be first. Biopharma A chooses to move into trials as quickly as possible, while Biopharma B decides to address broader solubility concerns first. Who gets to market first may ...

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Importance of Metadata Cataloging in Research IMPORTANCE OF METADATA CATALOGING IN RESEARCH

whitepaper

Feb 20, 2018

Data sprawl is a systemic problem across both government and private industry. There is a struggle in most environments to understand what data exists in the environment, protect against loss of that data as employees transition, and proactively manage the valuable data assets. In research data, the...

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Patient Identity Management: A Dose of Patient-friendly Security for Medical Providers PATIENT IDENTITY MANAGEMENT: A DOSE OF PATIENT-FRIENDLY SECURITY FOR MEDICAL PROVIDERS

whitepaper

Feb 16, 2018

Every day, in hospitals and physician offices everywhere, healthcare providers are telling patients what’s good for them: exercise, eat better, quit smoking. No one would deny this is great advice but be getting the patient to follow it can be a challenge for reasons most of us know too well. ...

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Infusion vs. Injection: Considerations for Administering a Drug Compound Across Preclinical Research Areas INFUSION VS. INJECTION: CONSIDERATIONS FOR ADMINISTERING A DRUG COMPOUND ACROSS PRECLINICAL RESEARCH AREAS

whitepaper

Feb 15, 2018

An overview of limitations and considerations when injecting a drug compound. Information on optimizing the therapeutic index of a drug. Comparative research examples spanning a broad range of therapeutic areas that review both bolus and infusion methods

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BioProcess Containers – Materials Of Construction BIOPROCESS CONTAINERS – MATERIALS OF CONSTRUCTION

whitepaper

Feb 15, 2018

Single-use technology (SUT) products are widely accepted for the manufacturing of vaccines and biologics. The increase in adoption of single-use Thermo Scientific™ BioProcess Containers (BPCs) is a result of their demonstrated performance, and their cost- and timesaving benefits. The quality a...

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Manufacturing Cell Therapies Development Strategies for Commercial Vision MANUFACTURING CELL THERAPIES DEVELOPMENT STRATEGIES FOR COMMERCIAL VISION

whitepaper

Feb 13, 2018

In this white paper, Richard Grant, Global VP of Cell Therapy at Invetech, and Brian Hampson, VP of Manufacturing Development & Engineering at PCT, share their unique insights on the topic, including how to:Discover manufacturing equipment and strategies that maximize quality, scalability, and s...

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Effect of Insulin on Cell Growth and Virus Protection EFFECT OF INSULIN ON CELL GROWTH AND VIRUS PROTECTION

whitepaper

Feb 10, 2018

The goal of our project was to test insulin as a booster for cell growth and virus production. Insulin was chosen for many reasons. It is already used in cell culture, and it is approved by regulatory agencies. So this is in line with our mission to look for strategies that can be implemented quickl...

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Whitepaper: Bringing the Power of PCR DNA Identification to Food Safety WHITEPAPER: BRINGING THE POWER OF PCR DNA IDENTIFICATION TO FOOD SAFETY

whitepaper

Feb 01, 2018

The technology made it possible to identify the exact species of any organism, based on the tiniest bit of DNA- (or RNA-) containing residue. This is possible due to a very simple process that has now become largely automated. This whitepaper will discuss how PCR technology works withing a series of...

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Whitepaper: Phenotypic drug discovery with high content screening WHITEPAPER: PHENOTYPIC DRUG DISCOVERY WITH HIGH CONTENT SCREENING

whitepaper

Jan 25, 2018

Reasons for phenotypic vs. target based drug discovery strategies, challenges of and maximising return of phenotypic assays.High Content Screening with detailed multiparametric assays in conjunction with powerful data visualisation and machine-learning tools provide a promising way to achieve this g...

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Mass Spectrometric Analysis of Intact Complex Biotherapeutics MASS SPECTROMETRIC ANALYSIS OF INTACT COMPLEX BIOTHERAPEUTICS

whitepaper

Jan 20, 2018

The benefit of therapeutic antibodies is their ability to be inherently more selective than traditional small-molecule pharmaceuticals through specific binding activities, lower toxicity, and higher efficacy. And the proof of their benefits is in the numbers: The U.S. Food & Drug Administration ...

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Transforming Large Scale Genomics and Collaborative Research TRANSFORMING LARGE SCALE GENOMICS AND COLLABORATIVE RESEARCH

whitepaper

Jan 18, 2018

Discover how Intel is collaborating with the genomics community to transform large datasets into biomedical insights that accelerate personalized care, revolutionizing how genomic workflows get executed, stored, and processed at cloud scale.For years, many aspects of life sciences work have required...

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Application and Current Trends of Biotechnology: a Brief
Review APPLICATION AND CURRENT TRENDS OF BIOTECHNOLOGY: A BRIEF REVIEW

whitepaper

Jan 17, 2018

Biotechnology is defined as biology-based technology which uses organisms or their parts to make or modify products, or improve plants, animals and microorganisms. It is classified as animal biotechnology, environmental biotechnology, aquatic biotechnology, microbial biotechnology, medical biotechno...

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Solutions for the future of biomanufacturing SOLUTIONS FOR THE FUTURE OF BIOMANUFACTURING

whitepaper

Jan 15, 2018

Biomanufacturers today face new challenges to produce more efficiently, with increased quality. Many facilities have a mix of old and new equipment, often running independently on custom software. Intensified processes require a higher level of automation and often call for the rapid addition of sen...

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Genetic Engineering and Environmental Risk GENETIC ENGINEERING AND ENVIRONMENTAL RISK

whitepaper

Jan 10, 2018

Genetic engineering in today’s world is gaining much importance. It provides plant varieties with good agronomic characteristics, superior quality values and expressing traits of agricultural interest such as insect resistance and herbicide tolerance. The production and use of genetically modi...

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Achieving Operational Efficiencies for Healthcare Organizations ACHIEVING OPERATIONAL EFFICIENCIES FOR HEALTHCARE ORGANIZATIONS

whitepaper

Jan 10, 2018

Healthcare organizations are working hard to meet constituent demands for better IT services and efficiency. With huge investments in their 3-tier systems and other aging infrastructure, they are now seeking better ways to innovate and eliminate legacy complexity. This paper explains how Nutanix ena...

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Sepsis and the Receding Grail SEPSIS AND THE RECEDING GRAIL

whitepaper

Jan 05, 2018

Sepsis is a life-threatening illness culminating in multi-organ dysfunction paired with a systemic inflammatory response. The disease burden is considerable: it is the single most expensive condition treated in hospitals, with annual costs in the US projected at nearly $24bn.

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How the techniques of molecular biology are developed
from natural systems HOW THE TECHNIQUES OF MOLECULAR BIOLOGY ARE DEVELOPED FROM NATURAL SYSTEMS

whitepaper

Jan 02, 2018

A striking characteristic of the highly successful techniques in molecular biology is that they are derived from natural occurring systems. RNA interference (RNAi), for example, utilises a mechanism that evolved in eukaryotes to destroy foreign nucleic acid.

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Biopreservation Best Practices: A Cornerstone in the Supply Chain of Cell-based Therapies – MSC Model Case Study BIOPRESERVATION BEST PRACTICES: A CORNERSTONE IN THE SUPPLY CHAIN OF CELL-BASED THERAPIES – MSC MODEL CASE STUDY

whitepaper

Jan 02, 2018

Mesenchymal stromal cells (MSCs) are prime candidates for regenerative medicine and therapeutic applications due to both their potent immunomodulatory function and a unique ability to proliferate and differentiate into a variety of cell lineages. However, the stresses incurred during biopreservation...

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The Effect of Geographic Breadth on Enrollment THE EFFECT OF GEOGRAPHIC BREADTH ON ENROLLMENT

whitepaper

Dec 20, 2017

Download this in-depth white paper on the effect of geographic breadth on enrollment in clinical trials of five high-interest diseases and how location, as well as the total number of countries, included affecting successful targeting of the right markets and patient populations.

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Biopreservation Best Practices: A Cornerstone in the Supply Chain of Cell-based Therapies – MSC Model Case Study BIOPRESERVATION BEST PRACTICES: A CORNERSTONE IN THE SUPPLY CHAIN OF CELL-BASED THERAPIES – MSC MODEL CASE STUDY

whitepaper

Dec 18, 2017

Mesenchymal stromal cells (MSCs) are prime candidates for regenerative medicine and therapeutic applications due to both their potent immuno-modulatory function and a unique ability to proliferate and differentiate into a variety of cell lineages. However, the stresses incurred during bio preservati...

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The Year in CRISPRs THE YEAR IN CRISPRS

whitepaper

Dec 17, 2017

The news was full of CRISPR developments in 2015. New insights into the structures and mechanisms of CRISPR systems were reported. New tools and techniques were introduced. And new applications were explored. The newest CRISPR developments usually appear in peer-reviewed studies that emphasize incre...

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WHITE PAPER ON CANCER CARERS WHITE PAPER ON CANCER CARERS

whitepaper

Dec 17, 2017

This White Paper is a joint collaboration between the European Cancer Patients Coalition (ECPC) and Eurocarers, aimed at presenting European policy-makers at the European Union (EU) and national level with policy recommendations for a robust policy framework supporting cancer carers. Carers are peop...

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South Shore Hospital - Case Study SOUTH SHORE HOSPITAL - CASE STUDY

whitepaper

Dec 08, 2017

As South Shore Health System sought to differentiate their care strategy for new mothers, they faced the challenge of establishing a consistent message across referring physicians as well as misinformation on social media. A branded mobile app allowed them to engage patients early, often, and direct...

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Advanced Biotechnology Tools for Invasive Species Management ADVANCED BIOTECHNOLOGY TOOLS FOR INVASIVE SPECIES MANAGEMENT

whitepaper

Dec 06, 2017

Increasingly, genetic tools are being used to detect and solve pressing environmental, social, and health-related challenges. It is clear that investments in technology innovation can be game changing, as advances in biotechnology may provide new methods to protect the nation’s resources from ...

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Advanced Biotechnology Tools for Invasive Species Management ADVANCED BIOTECHNOLOGY TOOLS FOR INVASIVE SPECIES MANAGEMENT

whitepaper

Dec 06, 2017

Increasingly, genetic tools are being used to detect and solve pressing environmental, social, and health-related challenges. It is clear that investments in technology innovation can be game changing, as advances in biotechnology may provide new methods to protect the nation’s resources from ...

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White Paper: Patterned Illumination for Optogenetics in Cell Biology WHITE PAPER: PATTERNED ILLUMINATION FOR OPTOGENETICS IN CELL BIOLOGY

whitepaper

Dec 02, 2017

Optogenetic approaches in cell biology applications are becoming more and more ubiquitous as molecular toolkits expand. However, identifying which pattern illumination technologies to use with them may be challenging. This white paper provides an overview of the molecular probes available to the cel...

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A New Pharmaceutical Commons: Transforming Drug Discovery A NEW PHARMACEUTICAL COMMONS: TRANSFORMING DRUG DISCOVERY

whitepaper

Nov 30, 2017

The Oxford Martin School at the University of Oxford is a worldleading centre of pioneering research that addresses global challenges. We invest in research that cuts across disciplines to tackle a wide range of issues such as climate change, disease and inequality. We support novel, high risk and m...

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An introduction to Next-Generation Sequencing Technology AN INTRODUCTION TO NEXT-GENERATION SEQUENCING TECHNOLOGY

whitepaper

Nov 30, 2017

DNAsequencinghascome a longway since the daysoftwo-dimensionalchromatography in the 1970s. With the advent of theSanger chain termination method1 in1977, scientistsgained the ability tosequenceDNAin a reliable, reproducible manner. Adecade later, Applied Biosystemsintroduced the first automated, cap...

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Choice Of Upstream Bioreactor Technologies For Industrial Scale Viral Manufacturing CHOICE OF UPSTREAM BIOREACTOR TECHNOLOGIES FOR INDUSTRIAL SCALE VIRAL MANUFACTURING

whitepaper

Nov 29, 2017

Gene therapy, including oncolytic viruses, where the new genetic material is introduced into the body, holds promise to cure or alleviate symptoms of many different diseases. In the last few years, the field has seen rapid growth with at least 11 drugs approved globally. A ClinicalTrials.gov search ...

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Mechanical regulation of musculoskeletal system development MECHANICAL REGULATION OF MUSCULOSKELETAL SYSTEM DEVELOPMENT

whitepaper

Nov 28, 2017

During embryogenesis, the musculoskeletal system develops while containing within itself a force generator in the form of the musculature. This generator becomes functional relatively early in development, exerting an increased mechanical load on neighboring tissues as development proceeds.

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GLOBAL AGRICULTURAL INFORMATION NETWORK GLOBAL AGRICULTURAL INFORMATION NETWORK

whitepaper

Nov 27, 2017

The Australian federal government is very supportive of biotechnology and has committed considerable
long-term funding to research and development. The Australian Productivity Commission recently
completed an inquiry into the regulatory burden on farm businesses focusing on regulations...

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2017 Agricultural Biotechnology Report 2017 AGRICULTURAL BIOTECHNOLOGY REPORT

whitepaper

Nov 27, 2017

The Australian federal government is very supportive of biotechnology and has committed considerable long-term funding to research and development. The Australian Productivity Commission recently completed an inquiry into the regulatory burden on farm businesses focusing on regulations that have a m...

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The science of gene therapy THE SCIENCE OF GENE THERAPY

whitepaper

Nov 23, 2017

Cells are the basic building blocks of all living things. The command center of each cell is called the nucleus, and it contains chromosomes. Chromosomes are made up of DNA the body’s hereditary material.Typically, every person has 2 copies of each gene one from each parent.A person has about ...

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Health reform 3.0: Thriving in a permanent state of policy disruption HEALTH REFORM 3.0: THRIVING IN A PERMANENT STATE OF POLICY DISRUPTION

whitepaper

Nov 17, 2017

The death of health reform has been greatly exaggerated. Though Congress was unable to pass a comprehensive national health reform bill in 2017, many other reforms are playing out in Congress, regulatory agencies and state capitals that could profoundly impact the healthcare landscape over the next ...

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Multiplying the Value of Wearables and Patient-Generated Health Data MULTIPLYING THE VALUE OF WEARABLES AND PATIENT-GENERATED HEALTH DATA

whitepaper

Nov 08, 2017

According to one recent survey, hospitals and health systems are no longer questioning the value – or desire – for Patient-Generated Health Data (PGHD). In fact, they are demanding it. Indeed, a 2018 HIMSS Media report found that 90 percent of those incorporating wearable devices in thei...

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Sizing up the Pregnancy and Lactation Labeling Rule SIZING UP THE PREGNANCY AND LACTATION LABELING RULE

whitepaper

Oct 30, 2017

As a strategic thought leader, Wolters Kluwer Clinical Drug Information partners with content experts to bring you the latest information on important changes in the healthcare space. This white paper is based on a presentation by Drs. Michael Schatz, Christina Chambers, and Allen A. Mitchell, three...

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Automatic calculation of HeLa cell culture confluency AUTOMATIC CALCULATION OF HELA CELL CULTURE CONFLUENCY

whitepaper

Oct 25, 2017

To obtain the maximum efficiency of transfection and avoid using expensive reagents for nothing, the cell confluency needs to be calculate with accuracy. Today, the majority of cell biologists estimate the cell confluency in culture flasks in a subjective way, looking at the amount of space covered ...

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THE HUMAN CELL ATLAS THE HUMAN CELL ATLAS

whitepaper

Oct 18, 2017

The Human Cell Atlas (HCA) will be made up of comprehensive reference maps of all human cells the fundamental units of life as a basis for understanding fundamental human biological processes and diagnosing, monitoring, and treating disease. It will help scientists understand how genetic variants im...

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DSM Looks to Challenge Traditional Stent Graft Materials with its Dyneema Purity® Membrane DSM LOOKS TO CHALLENGE TRADITIONAL STENT GRAFT MATERIALS WITH ITS DYNEEMA PURITY® MEMBRANE

whitepaper

Oct 17, 2017

A rising global demand for more minimally invasive surgeries to treat both cardiovascular and peripheral arterial diseases are driving the market to look for new and more efficient materials to construct stent grafts used in those procedures.Download this whitepaper to learn more about DSM and the b...

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The Scientific Path To Cycle Development THE SCIENTIFIC PATH TO CYCLE DEVELOPMENT

whitepaper

Oct 10, 2017

Management of medication delivery through lyophilization - freeze-drying - is a crucial enabling process technology for many important parenteral drugs. Close to 50% of biopharmaceuticals, including enzymes, proteins and monoclonal antibodies, must be lyophilized as these therapeutic agents are insu...

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Liposome Technology LIPOSOME TECHNOLOGY

whitepaper

Oct 09, 2017

Polymun offers the development of liposomal formulations for all kinds of pharmaceutically active ingredients and vaccine antigens. A broad spectrum of analytical methods has been established for this purpose. Polymun produces GMP material including all necessary documentation for IMPD/IND. We also ...

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Where Compassion and Technology Meet: Children’s Mercy WHERE COMPASSION AND TECHNOLOGY MEET: CHILDREN’S MERCY

whitepaper

Oct 01, 2017

Young patients and their caregivers who enter Children’s Mercy Adele Hall are greeted by displays of colorful characters mounted from the ceiling and walls, whimsical designs and vibrant furnishings. But there’s much more to this facility than its cheerful decor. Children’s Mercy H...

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Human Adult Stem Cells: Their Biosafety and Current Status in Cell-based Therapy HUMAN ADULT STEM CELLS: THEIR BIOSAFETY AND CURRENT STATUS IN CELL-BASED THERAPY

whitepaper

Sep 22, 2017

Human adult stem cells have attracted considerable interest in the field of regenerative medicine in recent years. Adult stem cells include mesenchymal stem cells, neural stem cells, hematopoietic stem cells, cardiac stem cells, hepatic stem cells etc.They are capable of differentiating into the maj...

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Advancing therapeutic antibody discovery with multiplexed screening ADVANCING THERAPEUTIC ANTIBODY DISCOVERY WITH MULTIPLEXED SCREENING

whitepaper

Sep 21, 2017

In this whitepaper, IntelliCyt Corporation describe how the iQue Screener is used to perform multiplexed screens for antibody binding to either cell surface or to circulating target antigens.Antibody-based therapeutics are the fastest growing and most successful therapeutic modality for treating dis...

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GENE BLOCKCHAIN PLATFORM GENE BLOCKCHAIN PLATFORM

whitepaper

Sep 18, 2017

Human genome data will be not just government or high-tech companies' privilege, but also walk into ordinary people's life.

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Advantages of long reads for genome assembly ADVANTAGES OF LONG READS FOR GENOME ASSEMBLY

whitepaper

Sep 15, 2017

Over the last decade, improvements in next generation DNA sequencing technology have transformed the field of genomics, making it an essential tool in modern genetic and clinical research laboratories. The facility to sequence whole genomes or specific genomic regions of interest is delivering new i...

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An introduction to Next-Generation Sequencing Technology AN INTRODUCTION TO NEXT-GENERATION SEQUENCING TECHNOLOGY

whitepaper

Sep 07, 2017

DNAsequencinghascome a long way since the days of two-dimensional chromatography in the 1970s. With the advent of the anger chain termination method1 in1977, scientists gained the ability tosequenceDNAin a reliable, reproducible manner. A decade later, Applied Biosystems introduced the first automat...

Read More

Preparing for Private Cloud and Hybrid IT with Red Hat
Cloud Infrastructure PREPARING FOR PRIVATE CLOUD AND HYBRID IT WITH RED HAT CLOUD INFRASTRUCTURE

whitepaper

Sep 01, 2017

A primary challenge in today's enterprise is how to adopt these new technologies and methodologies. Most organizations can't start completely anew because of the large investment required and, equally important, the continued reliance on existing infrastructure and traditional applications&n...

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Antimicrobial Resistance Benchmark 2018 ANTIMICROBIAL RESISTANCE BENCHMARK 2018

whitepaper

Aug 15, 2017

The global healthcare system depends on appropriate and timely access to antimicrobials. Without antibiotics, there is no direct treatment for infections, no safe surgery, no emergency medicine. The unchecked rise of Antimicrobial Resistance (AMR) puts this at risk for us all. While AMR results from...

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Selecting the Best Microfluidics Device Material for Your In Vitro Diagnostic SELECTING THE BEST MICROFLUIDICS DEVICE MATERIAL FOR YOUR IN VITRO DIAGNOSTIC

whitepaper

Aug 03, 2017

“In vitro diagnostics” is a term for a broad industry encompassing everything from benchtop or larger bioanalytical instrumentation applications such as protein analysis and next generation sequencing to point of care devices. As if in vitro diagnostic (IVD) development wasn’t diff...

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Rapid, real-time pathogen identification and antimicrobial resistance profiling RAPID, REAL-TIME PATHOGEN IDENTIFICATION AND ANTIMICROBIAL RESISTANCE PROFILING

whitepaper

Jul 11, 2017

Whether airborne or present in food and water supplies, pathogens have the potential to affect agriculture and human health profoundly. Livestock infectious diseases can have an influence on animal welfare and global food production. Crop pathogens are also a serious problem, especially in agricultu...

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Big Data Lipidomics for Lipid Biomarker Identification and Drug Discovery BIG DATA LIPIDOMICS FOR LIPID BIOMARKER IDENTIFICATION AND DRUG DISCOVERY

whitepaper

Jul 04, 2017

Lipidomics is the large-scale study of lipids in biological systems. The analysis of large  datasets, potentially containing up to thousands of lipidomes, is a challenging endeavour.  We have established multiparametric statistical approaches, tailored to  quantify lipid data. These m...

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Authenticating human cell lines using the Identifiler kits and capillary electrophoresis platforms AUTHENTICATING HUMAN CELL LINES USING THE IDENTIFILER KITS AND CAPILLARY ELECTROPHORESIS PLATFORMS

whitepaper

Jul 04, 2017

The study of human diseases relies heavily on the analysis of dissociated human cell lines grown in culture. However, an increasingly acknowledged problem is that cells grown in vitro can be misidentified or become contaminated with other unrelated cell lines . Misidentification of cell lines produc...

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Blockchain-enabled genomic data sharing and analysis platform BLOCKCHAIN-ENABLED GENOMIC DATA SHARING AND ANALYSIS PLATFORM

whitepaper

Jul 02, 2017

Deoxyribonucleic acid, or DNA, is a molecule that encodes the blueprint of every living organism. DNA is a chain-like molecule of variable length made of four building blocks, commonly called letters (Figure 1). The four letters of DNA are adenine (A), thymine (T), cytosine (C), and guanine (G). Thu...

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STRUCTURAL VARIATION IN THE HUMAN GENOME STRUCTURAL VARIATION IN THE HUMAN GENOME

whitepaper

Jun 14, 2017

Structural variation accounts for much of the variation among human genomes. Structural variants of all types are known to cause Mendelian disease and contribute to complex disease. Learn how long-read sequencing is enabling detection of the full spectrum of structural variants to advance the study ...

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The evolution of clinical research in East Asia THE EVOLUTION OF CLINICAL RESEARCH IN EAST ASIA

whitepaper

Jun 06, 2017

Clinical research has become increasingly globalized and trial activity has steadily increased in East Asia, which is home to 22% of the world’s population. This analysis takes a look at how has clinical research has evolved in this region, providing insights by leveraging Trialtrove® and ...

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The Paperless Future of Healthcare and Life Sciences THE PAPERLESS FUTURE OF HEALTHCARE AND LIFE SCIENCES

whitepaper

Jun 05, 2017

Your management and IT departments are driving towards tomorrow’s wholly digital world, making critical technology investments in an effort to streamline your business. Unfortunately, they often overlook a critical last step. A hospital or medical office might be state of the art until a patie...

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A Closer Look At Cannabis Testing A CLOSER LOOK AT CANNABIS TESTING

whitepaper

Jun 04, 2017

Cannabis has demonstrated health benefits since ancient times. While less than 6% of today’s studies on marijuana analyze its medical properties, publications to date indicate that cannabis shows great promise for the treatment of many diseases and symptoms (Table 1). However, patients with ca...

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Building The Digital Biotech Company: BUILDING THE DIGITAL BIOTECH COMPANY:

whitepaper

Jun 01, 2017

Our business strategy involves progressing mRNA medicines for many therapeutic areas and diseases simultaneously, all built from our core mRNA platform. To propel this strategy, we have created a business model and infrastructure quite distinct in the biopharmaceutical space. Digitization is a core ...

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mRNA Vaccines: Disruptive Innovation in Vaccination MRNA VACCINES: DISRUPTIVE INNOVATION IN VACCINATION

whitepaper

May 25, 2017

Vaccines to prevent infectious diseases are the greatest medical innovation of all time. The CDC estimates that U.S. childhood vaccinations given in the past two decades will prevent Americans from 322 million illnesses, 21 million hospitalizations, 732,000 deaths, $295 billion of direct costs, and ...

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Next-Generation Sequencing Assay Validation A Practical Guide for the Clinical Genomics Laboratory NEXT-GENERATION SEQUENCING ASSAY VALIDATION A PRACTICAL GUIDE FOR THE CLINICAL GENOMICS LABORATORY

whitepaper

May 10, 2017

Next-generation sequencing (NGS) has revolutionized the field of genomics and how in vitro diagnostic (IVD) test developers, laboratories, and clinicians are diagnosing, treating, and monitoring disease. Before you can successfully launch a clinical assay, platform, or service, you need to be absolu...

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Cybersecurity in Health: Using a trusted cloud solution to help ensure data is managed, protected, private, and compliant CYBERSECURITY IN HEALTH: USING A TRUSTED CLOUD SOLUTION TO HELP ENSURE DATA IS MANAGED, PROTECTED, PRIVATE, AND COMPLIANT

whitepaper

May 09, 2017

Too many organizations don’t realize how sophisticated cyberattacks have become. Hackers are no longer mischievous high school kids hiding in their parents’ basements. They are well organized, with tools in their arsenals that include easily obtainable software development kits complete ...

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Addressing the challenges of metagenomics for environmental and clinical research ADDRESSING THE CHALLENGES OF METAGENOMICS FOR ENVIRONMENTAL AND CLINICAL RESEARCH

whitepaper

Apr 19, 2017

The genomic analysis of multiple organisms obtained from a single sample commonly referred to as “metagenomics”, allows a great insight into the genetic makeup of microbial communities. Traditionally, microorganisms have been studied through the culturing of individual species or strains...

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