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Webinars

Phenotyping the tumor micro-environment with advanced tissue-based multiplexing assays
PHENOTYPING THE TUMOR MICRO-ENVIRONMENT WITH ADVANCED TISSUE-BASED MULTIPLEXING ASSAYS
The benefits of multiplex immunohistochemistry assays for tissue analysis are numerous. High-level multiplexing, whole slide imaging, workflow compatibility, and spatial analysis are all must-have requirements for effective multiplex IHC solutions. This webinar will provide insight into how Ultivue&...

Profiling clonal hematopoiesis in cancer survivors with single-cell DNA sequencing
PROFILING CLONAL HEMATOPOIESIS IN CANCER SURVIVORS WITH SINGLE-CELL DNA SEQUENCING
Cure rates for children with cancer have increased dramatically over the past 40 years with the advent of modern treatment strategies, but most patients have serious life-long medical conditions as a result of the toxicity of their treatments. Clonal hematopoiesis of indeterminate potential (CHIP) i...

Big advance in contact-free movement of tiny amounts of liquid
BIG ADVANCE IN CONTACT-FREE MOVEMENT OF TINY AMOUNTS OF LIQUID
Acoustic liquid handlers have been available for more than a decade. They enable nanoliters of liquid to be accurately transferred from one well to another, without any risk of contamination or loss. The liquid handlers adapt to different fluid types and enable direct dilution of a liquid rather tha...

Magnetic 3D Bioprinting of Cells: Overcoming Imaging Obstacles in Spheroids
MAGNETIC 3D BIOPRINTING OF CELLS: OVERCOMING IMAGING OBSTACLES IN SPHEROIDS
Interest in 3D cell culture has grown exponentially in recent years, partially due to 3D cultures helping to overcome the challenges of using animal models and inadequacy of 2D cultures.  Challenges are still present because of the physical nature of 3D cultures, especially when using confocal ...

Insights into Recent Developments in Protein A Chromatography
INSIGHTS INTO RECENT DEVELOPMENTS IN PROTEIN A CHROMATOGRAPHY
Protein A-based chromatography is the primary method used to purify monoclonal antibodies (mAbs). Over the past decade, there has been significant development of Protein A media, resulting in both higher capacity and improved stability to meet the changing requirements of the industry. More improvem...

Utilizing Extracellular Matrix to Enhance Multicellular Tumor Spheroid Models for Proliferation and Invasion
UTILIZING EXTRACELLULAR MATRIX TO ENHANCE MULTICELLULAR TUMOR SPHEROID MODELS FOR PROLIFERATION AND INVASION
This technical video provides an overview of the methodologies, tools, and reagents used to generate multicellular tumor spheroids. Specifically, this video discusses the benefits of Cultrex® extracellular matrices for spheroid formation and analysis. Technical tips are provided for using colori...

A Systematic PDX-Based Solution for Preclinical Biomarker Discovery
A SYSTEMATIC PDX-BASED SOLUTION FOR PRECLINICAL BIOMARKER DISCOVERY
Tumor heterogeneity is a major hurdle for cancer treatment success. To effectively enroll patients in clinical trials, the identification of predictive biomarkers at the preclinical stage is crucial. The use of patient-derived xenograft (PDX) tumor models facilitates the identification of biomarkers...

3D Tumor Models: Predicting Better In Vivo and Translational Results
3D TUMOR MODELS: PREDICTING BETTER IN VIVO AND TRANSLATIONAL RESULTS
In a constant battle to find more efficient and effective ways to test oncology preclinical candidates, 3D in vitro culture methods for PDX-derived tumor cells have shown promise of in vivo-like growth characteristics, invasion, and responses to therapeutics. With these methods, we can perform high-...

MANAGING BIOLOGICS PROCESS ANALYTICAL TECHNOLOGY IN PFIZER
MANAGING BIOLOGICS PROCESS ANALYTICAL TECHNOLOGY IN PFIZER
Coordinating PAT between development and manufacturing organizations is always challenging. When there are multiple development sites and numerous manufacturing sites, this becomes especially challenging. In order to help manage this in an efficient manner, we have established a PAT SME network with...

Breaking Down Barriers in Healthcare: Urgency for the Clinical Laboratory to Migrate from the Background to the Forefront of Patient Care
BREAKING DOWN BARRIERS IN HEALTHCARE: URGENCY FOR THE CLINICAL LABORATORY TO MIGRATE FROM THE BACKGROUND TO THE FOREFRONT OF PATIENT CARE
The movement towards value-based healthcare has provided a platform for a better future for all involved in the health ecosystem. However, amongst the multitude of value initiatives, the clinical laboratory has largely been left to play a secondary role. Despite its core value principles of data, ti...

Knock out biologic quant and quality on a tiny sample
KNOCK OUT BIOLOGIC QUANT AND QUALITY ON A TINY SAMPLE
Collecting quantification and characterization data of biologics often requires a large amount of protein and multiple instruments. In this webinar, see how Lunatic makes batch-wise concentration measurements a breeze by using just 2 µL of sample and eliminating dilution steps and cross-contam...

Strategies to normalize miRNA expression in serum and plasma
STRATEGIES TO NORMALIZE MIRNA EXPRESSION IN SERUM AND PLASMA
MicroRNA(miRNA) are short non-coding single-stranded RNA molecules that regulate gene expression at the post-transcriptional level.  They are known to play a critical role in multiple biological processes including proliferation, differentiation, apoptosis, and hematopoiesis. Dysregulation of m...

It’s Never Too Late: Improve Clinical Trial Processes with a Unified Platform
IT’S NEVER TOO LATE: IMPROVE CLINICAL TRIAL PROCESSES WITH A UNIFIED PLATFORM
As scientific innovation has led to new trial designs, modern cloud technologies have enabled the industry to better manage how clinical trials are executed. Newer, more advanced cloud applications now offer unified data and process models, allowing organizations to manage their end-to-end clinical ...

Reconfirming the Group A Strep Diagnostic Algorithm with Molecular Confirmation
RECONFIRMING THE GROUP A STREP DIAGNOSTIC ALGORITHM WITH MOLECULAR CONFIRMATION
Group A Streptococcus (Group A Strep) remains fairly unchanged and is well-understood by the scientific community. However, our methods of detection have significantly improved as have various options for testing. With so many advancements in the landscape of molecular diagnostics, it is vital for a...

DNA Sequencing For Cancer Research
DNA SEQUENCING FOR CANCER RESEARCH
Through genomic sequencing and analysis, clinicians can identify specific mutations present in a patient’s cancer cells and deliver personalized treatment based on the genetic information. Increased availability and lower costs of next-generation sequencing (NGS) and analysis, along with the o...

Comprehensive Capture of Human Neuropathology by Multiplexed Ion Beam Imaging (MIBI)
COMPREHENSIVE CAPTURE OF HUMAN NEUROPATHOLOGY BY MULTIPLEXED ION BEAM IMAGING (MIBI)
Single cell analysis, starting with the earliest low parameter fluorescent experiments, helped define the major cell subsets of human cellular systems as we understand them today. Now, a novel combination of single cell analysis and metal isotopes based mass spectrometry (MIBI) offers a routine exam...

Soft Tissue Cancer-IHC Webinar
SOFT TISSUE CANCER-IHC WEBINAR
Soft tissue tumors are a broad group of neoplasms that involve the connective tissue of the body. Each year, over 13,000 people in the US are diagnosed with soft tissue sarcomas and over 5,000 people succumb to the malignancy. Because soft tissue sarcomas are very ambiguous and amorphous, many time ...

Lymphomas and Leukemias
LYMPHOMAS AND LEUKEMIAS
Leukemia and lymphoma are hematologic neoplasms that affect members of all age groups. Each year, over 140,000 people in the US are diagnosed with a hematologic malignancy of some kind. With constant advancement of treatment options, the importance of accurate diagnosis and detection of lymphomas an...

The Microbiome: Vital Cells of Existence
THE MICROBIOME: VITAL CELLS OF EXISTENCE
For every cell in your body, there’s another tiny single-celled creature that also calls your body home. Far from being germs, we should eradicate, these ancient friends allow us to digest food, breathe air, and fight off disease. They were here long before us and will undoubtedly remain long ...

Trends in Synthetic Biology: Antibody Engineering
TRENDS IN SYNTHETIC BIOLOGY: ANTIBODY ENGINEERING
As the body’s circulating army of first responders, antibodies recognize and destroy foreign and potentially disease-causing pathogens. The engineering of synthetic antibody forms and conjugates has produced a whole new arsenal of tools for applications in research, diagnostics, and therapeuti...

The Clinical Impact of TP53 Inclusion in Multi-Gene Panels
THE CLINICAL IMPACT OF TP53 INCLUSION IN MULTI-GENE PANELS
Multi-Gene panel-based genetic testing has emerged as the standard of care for cancer genetic testing. This has led to the identification of TP53 mutations among individuals without classic personal or family histories of Li-Fraumeni syndrome. These mutations may be due to mosaicism, clonal hematopo...

Talking to Patients about Genetic Testing and the Potential Psychosocial Implications of that Discussion
TALKING TO PATIENTS ABOUT GENETIC TESTING AND THE POTENTIAL PSYCHOSOCIAL IMPLICATIONS OF THAT DISCUSSION
Dr. Hurley will provide an overview of psychosocial challenges faced by patients deciding to undergo genetic testing.  Her presentation will combine research findings from psychosocial research and case illustrations from twenty years of providing psychotherapy to genetic counseling patients.&n...

Accelerating Biology: New Product Innovations from 10x Genomics
ACCELERATING BIOLOGY: NEW PRODUCT INNOVATIONS FROM 10X GENOMICS
Multicellular organisms and dynamic biological processes consist of a complex and coordinated interplay of multiple individual cells. Until recently, most molecular studies have relied on bulk analysis, combining all cells into a single average readout. In recent years, single-cell RNA sequencing te...

Seeing Beyond the Greyscale: Rapid Elemental Characterisation of Biological Samples
SEEING BEYOND THE GREYSCALE: RAPID ELEMENTAL CHARACTERISATION OF BIOLOGICAL SAMPLES
Precise identification and localization of molecules and organelles on the sub-cellular level are essential for a comprehensive understanding of key processes within biological samples. To achieve this, researchers utilize advanced microscopy techniques such as super-resolution microscopy and transm...

GENETICS IN YOUR CLINIC: WHAT YOU CAN AND SHOULD DO NOW
GENETICS IN YOUR CLINIC: WHAT YOU CAN AND SHOULD DO NOW
As we learn more about the contribution of genetic and genomic factors to the origin, natural history, and treatment of human disease, clinicians are assuming more responsibility for ordering genetic tests for their patients. This, plus the emergence of Precision Medicine and the growing availabilit...

A Virtual Destination for Laboratory Professionals
A VIRTUAL DESTINATION FOR LABORATORY PROFESSIONALS
Cardinal Health™ labXchange is a no-cost online destination where lab professionals have access to exhibits, live webinars and product demonstrations in one convenient location. Hear from leading experts on industry related topics - reimbursements, big data, emerging diseases, IQCP and more. I...

HUMANIZED MOUSE MODELS: APPLICATIONS IN ONCOLOGY AND INFECTIOUS DISEASE
HUMANIZED MOUSE MODELS: APPLICATIONS IN ONCOLOGY AND INFECTIOUS DISEASE
"Humanized mouse models, where human tumor tissue is engrafted into immunodeficient mouse models, are now being used in oncology and infectious disease studies to provide valuable translational insight. In this webinar, our panel of experts will discuss the successes and caveats of using humani...

Microbiology and Immunology 2018
MICROBIOLOGY AND IMMUNOLOGY 2018
Our 4th Annual Microbiology and Immunology Virtual Conference is now available On Demand! Participants will explore and discover new concepts, tools and techniques to apply to ongoing research and diagnostics. Microbiology and Immunology cover an array of industries and disciplines, encompassing var...

2019 Joint Commission National Patient Safety Goals: Update and Practical Advice
2019 JOINT COMMISSION NATIONAL PATIENT SAFETY GOALS: UPDATE AND PRACTICAL ADVICE
Understand the update of the National Patient Safety Goals to be sure your organization is in compliance with the requirements. Each year healthcare providers must meet the requirements of the Joint Commission's National Patient Safety Goals as part of the accreditation process. Receive an overv...

Ethical Considerations When Managing Patients
ETHICAL CONSIDERATIONS WHEN MANAGING PATIENTS' PAIN
Gain an understanding of how to help maintain the proper ethical pain management of patients. We are practicing in the midst of a national crisis in which every day over 130 people in the US die of overdosing from narcotic prescriptions overdose, heroin, and other related drugs. The pain was describ...

Flexible manufacturing strategies for cell and gene therapy products
FLEXIBLE MANUFACTURING STRATEGIES FOR CELL AND GENE THERAPY PRODUCTS
There is a clear call to automate manufacturing for cell and gene therapy products, but when should you automate? In this session, we will consider the shifting priorities as you move from product development towards clinical manufacturing and discuss how choosing the right type of automation can cr...

Laboratory Animal Sciences 2019
LABORATORY ANIMAL SCIENCES 2019
Digital transformation has affected the clinical phase of the drug development journey by improving efficiencies, patient engagement and allowing for utilization of computational and other technologies. This track will address topics such as data collection, flow, storage and analytics and digital t...

Better Science Through Imaging
BETTER SCIENCE THROUGH IMAGING
The Tilt from Mizar Imaging is a modular light sheet illumination system designed for high-resolution imaging. Mounting to most inverted microscopes, the Tilt enables light sheet imaging to be easily added to an existing or new microscope system. Existing light sheet microscopes use low(ish) NA dete...

The Secret to Improving the Therapeutic Index of Antibody Drug Conjugates
THE SECRET TO IMPROVING THE THERAPEUTIC INDEX OF ANTIBODY DRUG CONJUGATES
Antibody-drug conjugates (ADCs) were initially developed to provide a selective targeting mechanism for cytotoxic small molecule drugs with the goal of improving the therapeutic index in clinical practice. But despite a careful target selection and a high degree of specificity afforded through the a...

Virtual Clinical Trials Are Here: What Now?
VIRTUAL CLINICAL TRIALS ARE HERE: WHAT NOW?
Virtual or “siteless” clinical trials allow trial coordinators and patients to conduct clinical study visits via online video calls and collect data via handheld or wearable devices. In addition, virtual trials increase the size and diversity of the patient pool, accelerate recruiting, a...

Using CRISPR-Cas Screens to Reveal Fitness Genes and to Map Genetic Interactions
USING CRISPR-CAS SCREENS TO REVEAL FITNESS GENES AND TO MAP GENETIC INTERACTIONS
Genomic analyses are yielding a host of new information on the multiple genetic abnormalities associated with specific types of cancer. A comprehensive description of cancer-associated genetic abnormalities can improve our ability to classify tumors into clinically relevant subgroups and sometimes i...

Optimize This! Enhancing the Quality and Consistency of Cannabis and Extraction
OPTIMIZE THIS! ENHANCING THE QUALITY AND CONSISTENCY OF CANNABIS AND EXTRACTION
Everyone makes the best extracts. But are they optimized? And what does “the best” mean; does it mean high yield, high quality, or both? And what is quality anyway? Quality begins in the cultivation process and continues throughout the handling of the product from seed to sale. At OutCo,...

Is Your Biotherapeutic Immunomodulatory? How to Use Immunoassays to Get the Right Answer
IS YOUR BIOTHERAPEUTIC IMMUNOMODULATORY? HOW TO USE IMMUNOASSAYS TO GET THE RIGHT ANSWER
Biotherapeutics are a class of large medicinal products that are being increasingly used for various medical applications including vaccination, therapeutic drug delivery systems and the treatment of human diseases. Biotherapeutics offer the advantages of increased specificity and reduced toxicity c...

Characterization of Extracellular Vesicles with Nanoscale Flow Cytometry
CHARACTERIZATION OF EXTRACELLULAR VESICLES WITH NANOSCALE FLOW CYTOMETRY
In this webinar, we will discuss how to set up and utilize a flow cytometer for nanoparticle analyses.  We will first describe how to properly set up and clean a flow cytometer for small-particle experiments.  Next, we will characterize the scatter and fluorescence sensitivity of the CytoF...

MicroRNAs as biomarkers and therapeutic targets in TNBC
MICRORNAS AS BIOMARKERS AND THERAPEUTIC TARGETS IN TNBC
Triple-negative breast cancer accounts for a disproportionate share of the total breast cancer morbidity rate due to its aggressive behavior and lack of effective targets. Join Dr. Brian Adams of Harvard Medical School as he discusses how microRNAs can serve as superior therapeutic agents in th...

Tau Biology and Pathology in and Beyond Alzheimer’s Disease
TAU BIOLOGY AND PATHOLOGY IN AND BEYOND ALZHEIMER’S DISEASE
Watch this on-demand webinar presented by Dr. Akihiko Takashima and Dr. Ioannis (John) Sotiropoulos and learn about the emerging views on the role and function of Tau in neurons - including its recently suggested contributions to scaffolding and signaling. 

Triple Negative Breast Cancer Risk Genes Identified by Multigene Hereditary Cancer
TRIPLE NEGATIVE BREAST CANCER RISK GENES IDENTIFIED BY MULTIGENE HEREDITARY CANCER
In this webinar, Dr. Couch will present results from a recent study of multigene hereditary cancer panel testing in >10,000 women with triple-negative breast cancer (TNBC), focusing on the prevalence of cancer gene mutations among TNBC cases along with gene-specific associations with TNBC among C...

Genomics and the Future of Human Reproduction
GENOMICS AND THE FUTURE OF HUMAN REPRODUCTION
For most of humanity’s existence, we had only one way to make babies. The last century or so have seen the beginnings of change, with artificial insemination, in vitro fertilization, and prenatal and preimplantation genetic testing. The rest of this century will see astonishing changes, made b...

Maize genome complexity traversed with Oxford Nanopore technology
MAIZE GENOME COMPLEXITY TRAVERSED WITH OXFORD NANOPORE TECHNOLOGY
Maize is one of the most economically important crops globally and much effort has been spent generating the high quality B73 reference genome. However, the 10 chromosome, 2.3 gigabase (Gb) B73 reference genome was a substantial challenge due to the fact it is comprised of 85% transposable elements,...

Food Safety Management Systems to Enhance Customer Experience
FOOD SAFETY MANAGEMENT SYSTEMS TO ENHANCE CUSTOMER EXPERIENCE
Restaurant cleanliness matters! It’s the most important driver of customer visitation (i.e., they come back more often and increase sales) and brand loyalty, just behind the importance of employee service and food quality attributes. Employee service, “cleanliness“, and how the emp...

Assessing Treatment Benefit in Immuno-Oncology
ASSESSING TREATMENT BENEFIT IN IMMUNO-ONCOLOGY
The management of cancer patients in clinical practice is undergoing a revolution due to the introduction of effective immunotherapy. Several different strategies currently rely on harnessing the immune system to fight tumors, leading to unprecedented therapeutic success. However, immunotherapy has ...

Targeting prostate cancer stem cells with T cell immunotherapy
TARGETING PROSTATE CANCER STEM CELLS WITH T CELL IMMUNOTHERAPY
In healthy tissue, a reservoir of stem cells gives rise to non-stem cells while simultaneously maintaining their own population. This enables potentially endless growth and recovery from damage. Cancer stem cells (CSC) sustain cancer growth in the same way as normal stem cells do in healthy tissues....

Novel Continuous and Manual Sampling Methods for Beef Trim Microbiological Testing
NOVEL CONTINUOUS AND MANUAL SAMPLING METHODS FOR BEEF TRIM MICROBIOLOGICAL TESTING
A new beef trim sampling concept has been developed through a joint R&D project with USDA Agricultural Research Service, Fremont, and Sentry Equipment. The methods developed from this effort have received a USDA Letter of No Objection. For beef trimmings, potential contaminants will be on t...

Food Adulteration Detection: Getting Out of the Lab Using Portable Spectroscopy
FOOD ADULTERATION DETECTION: GETTING OUT OF THE LAB USING PORTABLE SPECTROSCOPY
Food fraud is estimated to cost the world economy more than $49 billion per year. The 2013 horse meat scandal alone was reported to cost the UK economy more than £1 billion. The effects of food adulteration reach much further than just these serious economic consequences. The Chinese infant fo...

Key Considerations for the Successful Development of a Biologic: Seven Steps to Success
KEY CONSIDERATIONS FOR THE SUCCESSFUL DEVELOPMENT OF A BIOLOGIC: SEVEN STEPS TO SUCCESS
Understanding the biology of your therapeutic is key to effectively and efficiently progressing it from first principles, through safety assessment studies, and into clinical trials. The unique characteristics and specific biology of each large molecule therapeutic make it impossible to design a &ld...

EXTRACTABLES FROM SINGLE-USE BIOREACTORS/BAGS AND IMPACT ON CELL CULTURE PERFORMANCE
EXTRACTABLES FROM SINGLE-USE BIOREACTORS/BAGS AND IMPACT ON CELL CULTURE PERFORMANCE
Attribute Sciences, Process Development, Amgen Biopharmaceuticals are drugs manufactured by growing genetically engineered cells in bioreactors to produce a therapeutic protein. Plastic single-use bioreactors are of interest to biopharmaceutical drug manufacturers due to their significant environmen...

Turning Up the Volume on Cell Therapy Production
TURNING UP THE VOLUME ON CELL THERAPY PRODUCTION
The development of novel biotherapeutics is an essential element in generating the power to cure the incurable. With recent advances in cell and molecular biology, cell therapy has emerged as an effective means to treat a host of biological disorders. However, challenges remain for the clinical and ...

High Throughput, Low Volume Subvisible Particle Analysis
HIGH THROUGHPUT, LOW VOLUME SUBVISIBLE PARTICLE ANALYSIS
Subvisible particle analysis is a key predictor of protein drug stability and a key formulation, quality metric. However, current methods use large volumes of precious protein solutions and are labor- and time-intensive, making this data inaccessible during late-stage candidate screening or early in...

Multiplexing PCR Design Made Easy
MULTIPLEXING PCR DESIGN MADE EASY
Because of its reliability, sensitivity and low cost, PCR has become the backbone of modern diagnostics. In recent years, researchers have ingeniously capitalized on the fundamental nature of PCR through multiplexing reactions saving reagent costs, precious samples, and user time. Multiplexing has a...

The Cell Culture Revolution: Commercializing Therapeutic Cell Systems
THE CELL CULTURE REVOLUTION: COMMERCIALIZING THERAPEUTIC CELL SYSTEMS
The advent of recombinant antibody production in mammalian cell lines has revolutionized modern medicine. Clinical success of these agents has challenged the underlying biological manufacturing systems to produce quantities sufficient to supply the ever-expanding commercial markets. A fundamental fo...

Using Peptones to Achieve Diverse and Demanding Bioproduction Goals
USING PEPTONES TO ACHIEVE DIVERSE AND DEMANDING BIOPRODUCTION GOALS
As bioproduction requirements advance, it is critical to have consistent, high-quality media and supplements that continue to meet evolving industry needs. Peptones have been successfully used in bioproduction applications for more than 30 years to meet diverse and demanding production requirements....

High-Throughput Multiplexed Screening of TCR Signaling Inhibitors
HIGH-THROUGHPUT MULTIPLEXED SCREENING OF TCR SIGNALING INHIBITORS
T cells play a critical role in the adaptive immune response. In naive T cells, binding of the T-cell receptor (TCR) to peptides complexed with major histocompatibility complex triggers an intricate signaling mechanism leading to T-cell activation, proliferation, and production of cytokines. Modulat...

Characterization of Oral Gut-Selective vs. Systemic JAK Inhibitors in the Mouse Oxazolone Colitis Model
CHARACTERIZATION OF ORAL GUT-SELECTIVE VS. SYSTEMIC JAK INHIBITORS IN THE MOUSE OXAZOLONE COLITIS MODEL
Autoimmune diseases such as ulcerative colitis require chronic treatment that often causes systemic immunosuppression, increasing long term cancer and infection risk. Reducing systemic side effects with localized treatment would greatly benefit patients. This webinar will explore the spatial charact...

Current Landscape of Education for Genetic Counselors
CURRENT LANDSCAPE OF EDUCATION FOR GENETIC COUNSELORS
Although the genetic counselor workforce has grown by 88% in the past 10 years, a 2016 supply and demand report confirmed that the US is currently experiencing a shortage of genetic counselors engaged in direct patient care (Hoskovec et al., 2017). In response, there are a variety of efforts underwa...

RNA-Seq as a Complement to DNA Genetic Testing
RNA-SEQ AS A COMPLEMENT TO DNA GENETIC TESTING
In this presentation, Dr. Karam will summarize RNA-sequencing technologies. The focus of the presentation will be describing the use of these technologies to aid understanding and diagnosing genetic disease. Rachid obtained his medical degree in Brazil, at the Federal University of Health Scien...

Comprehensive Variation at Clinical-Population Scales
COMPREHENSIVE VARIATION AT CLINICAL-POPULATION SCALES
Precision medicine anticipates the clinical application of whole-genome sequencing (WGS), as evidenced by the commitment of large-scale clinical programs such as All of Us for generating and reporting WGS data for millions of individuals. Execution of the required data analysis, from sample accessio...

Novel Approaches to Quantitative Metabolomics
NOVEL APPROACHES TO QUANTITATIVE METABOLOMICS
A frequently challenging field, metabolomics is often considered the most direct approach to making quantitative measurements that can be related to the physiological state of an organism. In this exclusive online symposium, you will discover new and novel approaches to quantitative metabolomics as ...

Using Micro-CT Imaging for the Phenotyping and Analysis of Bone Architecture
USING MICRO-CT IMAGING FOR THE PHENOTYPING AND ANALYSIS OF BONE ARCHITECTURE
Micro-computed tomography (micro-CT) offers significant advantages over other X-ray imaging techniques in the field of bone research. Its high-level X-ray absorption enables good contrast and the ability to observe bone in very fine detail, not only in bone density studies but also those examining t...

Expanding Biobanking Size and Scope to Advance Big Data Discovery
EXPANDING BIOBANKING SIZE AND SCOPE TO ADVANCE BIG DATA DISCOVERY
Currently, the Cleveland Clinic Biorepository is an assembly of several biobanks together with the Lerner Research Institute. Excel spreadsheets track almost everything – and there are no universal LIS, SOPs, universal, centralized freezer monitoring, or means to electronically track patient t...

ADVANCES AND CHALLENGES IN VACCINE DEVELOPMENT AND MANUFACTURE
ADVANCES AND CHALLENGES IN VACCINE DEVELOPMENT AND MANUFACTURE
This webinar reviews the constraints and complexities of vaccine product development and manufacture. The evolution of bioprocess and analytics innovation and technologies to overcome these challenges are discussed. The strategy and leveraging of innovation and technology for rapid product developme...

Risk stratification of the apparently healthy population with ARCHITECT STAT High Sensitive Troponin-I
RISK STRATIFICATION OF THE APPARENTLY HEALTHY POPULATION WITH ARCHITECT STAT HIGH SENSITIVE TROPONIN-I
In this webinar, you will hear about a recently CE marked application for ARCHITECT STAT High Sensitive Troponin I, that aids in providing greater accuracy for estimation of risk for future cardiac events in apparently healthy people, when used in conjunction with clinical and diagnostics findings. ...

Medicare Provider Agreement Assignment Following Change of Ownership: Evaluating Automatic Assignment vs. Rejection
MEDICARE PROVIDER AGREEMENT ASSIGNMENT FOLLOWING CHANGE OF OWNERSHIP: EVALUATING AUTOMATIC ASSIGNMENT VS. REJECTION
This CLE webinar will guide healthcare counsel on navigating a change of ownership (CHOW) in healthcare transactions when Medicare provider agreements are involved. The panel will discuss the factors to consider when determining whether to accept or reject the assignment of the provider agreement an...

CRISPR-created Animal Models: The Technical Lowdown
CRISPR-CREATED ANIMAL MODELS: THE TECHNICAL LOWDOWN
Creating reproducible animal models for long-term studies can often be problematic due to the complexity of the genetic modification(s) required. Suboptimal design strategies compound the challenges by generating undesired genotypic or phenotypic results. CRISPR-Cas9 or zinc-finger nuclease (ZFN)-ba...

Cell Signaling and Metabolism: Bridging a Gap in Cancer Therapies
CELL SIGNALING AND METABOLISM: BRIDGING A GAP IN CANCER THERAPIES
That cancer cells display an altered metabolism has been known for almost a century, but the cell-signaling mechanisms responsible for this phenomenon are just beginning to be understood, with some drugs targeting key regulators of both cell metabolism and tumor progression. The repurposing of old d...

The Brain-Microbiome Axis: Links Between Neurological Disease and Microbiota
THE BRAIN-MICROBIOME AXIS: LINKS BETWEEN NEUROLOGICAL DISEASE AND MICROBIOTA
The human microbiome consists of trillions of commensal microbes. These include bacteria, fungi, and viruses, which naturally reside within the human body and have been documented to affect epigenetic mechanisms, metabolic activity, and immune system function. Researchers are now focusing on how mic...

Stem Cells: Opportunities, Hurdles, and Promises
STEM CELLS: OPPORTUNITIES, HURDLES, AND PROMISES
Since Sir. Martin Evans’ 1981 identification of embryonic stem cells in mice, stem cells have been at the center of the drive to revolutionize medicine and the drug discovery process. In 1998, human embryonic stem cells were grown in a lab, and the field was further boosted in 2006 with the pi...

CURRENT USP PERSPECTIVES ON A RAPID STERILITY TEST
CURRENT USP PERSPECTIVES ON A RAPID STERILITY TEST
The current growth-based Sterility Tests with at least 14-days incubation is not suitable for short-lived products. An expert panel was formed under the USP General Chapters– Microbiology Expert Committee to provide recommendations on user requirements specifications and candidate technologies...

Botanical Identification - Authentication vs Adulteration
BOTANICAL IDENTIFICATION - AUTHENTICATION VS ADULTERATION
This webinar addresses the complex methods of botanical identification of natural nutraceutical and functional foods, and how adulteration of substances is discovered. It’s an exciting journey through the realm of chemical marker compounds, ratio comparison, and the latest in quality assurance...

The 3 R’s of cancer therapy: Response, Resistance, and Relapse
THE 3 R’S OF CANCER THERAPY: RESPONSE, RESISTANCE, AND RELAPSE
The 3 R’s: Response, Resistance, and Relapse Simplistic View of Cancer: a Monolith Patterns of response and resistance. Tumors Have Many Clones. Not One 4 identical mutations shared by one region of the chest wall and perinephric metastasis Darwinian Selection and Branched Evolution Mutation V...

Recent advances in diagnostics and treatments - from small molecules to cellular therapies
RECENT ADVANCES IN DIAGNOSTICS AND TREATMENTS - FROM SMALL MOLECULES TO CELLULAR THERAPIES
The majority of clinically approved medicines are synthetic small molecules that modulate target activity, usually by inhibiting the function of a single protein. A fraction of these small molecule medicines exert their therapeutic effect by activating protein targets and disrupting protein-protein ...

IS INDIA ANYWHERE CLOSER TO IMPLEMENTING CONTINUOUS BIOPROCESSING
IS INDIA ANYWHERE CLOSER TO IMPLEMENTING CONTINUOUS BIOPROCESSING
Continuous processing has been widely employed in many biological manufacturing processes. In recent years it gained the momentum in the field of Biosimilar manufacturing due to an ever-increasing pressure for reduction in manufacturing costs. Potentially, the continuous processing offers Lower Cost...

MIXED MODE CHROMATOGRAPHY IN PURIFYING BIOLOGICS – OVERVIEW
MIXED MODE CHROMATOGRAPHY IN PURIFYING BIOLOGICS – OVERVIEW
The market for therapeutic proteins such as monoclonal antibodies (mAbs), growth hormones, other recombinant therapeutic proteins has grown tremendously in the last two decade. To compete in the biopharmaceutical market, we should identify, develop the high product producing clone and find the best ...

EVOLVE MANUFACTURING PROCESSES BY IMPLEMENTING DISRUPTIVE TECHNOLOGIES
EVOLVE MANUFACTURING PROCESSES BY IMPLEMENTING DISRUPTIVE TECHNOLOGIES
The desire for innovative technology that can eventually cause disruptive changes remains high in the biotech pharmaceutical industry. The road between pursuing and developing that technology to genuine implementing is not a smooth ride. In this webinar, the presenter identifies key challenges of im...

Recent Changes to Drug Approvals in China: Regulatory Consultation, IND Submission and Acceptance of Foreign Data in NDA
RECENT CHANGES TO DRUG APPROVALS IN CHINA: REGULATORY CONSULTATION, IND SUBMISSION AND ACCEPTANCE OF FOREIGN DATA IN NDA
Historically, the review and approval of a Chinese investigational new drug (IND) have taken a year or even longer to complete, and new drug application (NDA) approval for a new drug lagged behind Western countries by four or five years. Recently, the National Medical Products Administration announc...

Simplifying Clinical Data Flow from EDC to SDTM
SIMPLIFYING CLINICAL DATA FLOW FROM EDC TO SDTM
Recent trends in clinical trials – including the increasing availability of clinical, operational and real-world data streams – offer the opportunity to gain better insight over clinical R&D as never before, but poses interesting challenges with data aggregation, harmonization, and c...

Endodontic applications of microcomputed tomography for studying root canals
ENDODONTIC APPLICATIONS OF MICROCOMPUTED TOMOGRAPHY FOR STUDYING ROOT CANALS
Endodontics is a specialty within the field of dentistry concerned with the morphology, physiology, and pathology of the human dental pulp and periradicular tissues. Recent technological advancements have led to several new methods for visualizing the anatomy of the human teeth, but, over the last d...

Molecular Testing Guideline for Selection of Lung Cancer Patients
MOLECULAR TESTING GUIDELINE FOR SELECTION OF LUNG CANCER PATIENTS
The advent of targeted therapies based on predictive biomarkers has dramatically altered the role of the molecular pathologist in lung cancer patient care. This webinar reviews the new recommendations published in the revised 2018 CAP/IASLC/AMP lung cancer predictive biomarker guidelines (Lindeman e...

Genetics and Genomics 2018
GENETICS AND GENOMICS 2018
Our 6th Annual Genetics and Genomics Virtual Conference are now available On Demand! As the foundation of life, genetics provides a base for other sciences to grow from. This free on-demand event will cover the most recent and exciting advances in genetics research. Participants of the Genetics 2018...

Drug Development – The 6 Most Critical Reasons Why Drugs are Delayed When Planning and Conducting CTA/IND Enabling Studies
DRUG DEVELOPMENT – THE 6 MOST CRITICAL REASONS WHY DRUGS ARE DELAYED WHEN PLANNING AND CONDUCTING CTA/IND ENABLING STUDIES
Bringing a drug from discovery to market is an expensive and time-consuming business. Every drug that fails comes with a cost which could be both reputational and financial. Keeping your development program on track is therefore critical to success. In this webinar, our featured speaker will explore...

Telehealth drug prescribing & the opioid crisis: What every doctor needs to know
TELEHEALTH DRUG PRESCRIBING & THE OPIOID CRISIS: WHAT EVERY DOCTOR NEEDS TO KNOW
Why is there a good chance you're illegally prescribing medication over telehealth? How are telehealth prescribing rules changing with the opioid crisis? Is an in-person exam necessary for prescribing medication online? How does telehealth drug prescribing work across state lines or internationa...

Stunner bangs out protein quant and characterization in one shot
STUNNER BANGS OUT PROTEIN QUANT AND CHARACTERIZATION IN ONE SHOT
Quantification and quality measurements are both integral parts of protein characterization workflows. These parameters have previously been collected separately, simply due to the lack of tools that can measure both. In this webinar, Dr. Lisa Adamiak will discuss how Stunner enables researchers to ...

Advanced optical hematology technology for elevated analytical performance
ADVANCED OPTICAL HEMATOLOGY TECHNOLOGY FOR ELEVATED ANALYTICAL PERFORMANCE
Today, hematology analyzers can collect vast amounts of data about cell characteristics, that subsequently improve disease detection. Advanced systems can perform a complete blood count (CBC) and classify multiple cell types, including more than the normal five subclasses of mature white blood cells...

Current Controversies in the Epidemiology, Diagnosis, and Management of Vaginal Infections
CURRENT CONTROVERSIES IN THE EPIDEMIOLOGY, DIAGNOSIS, AND MANAGEMENT OF VAGINAL INFECTIONS
Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10 million office visits per year due to vaginal infections. The three main causes of infectious vaginitis are vulvovaginal candidiasis (VVC), trichomoniasis, and bacterial vaginosis (BV)....

Transforming Clinical Trial Operations: The Next Big Step
TRANSFORMING CLINICAL TRIAL OPERATIONS: THE NEXT BIG STEP
Research shows that today’s clinical technology landscape is siloed, prompting an industrywide move to unify clinical trial systems and streamline end-to-end processes for better visibility and improved study execution. In a recent industry survey, 99% of respondents reported the need to unify...

Oncology Drug Access Navigators - Benefits to Patients & Health Care Teams
ONCOLOGY DRUG ACCESS NAVIGATORS - BENEFITS TO PATIENTS & HEALTH CARE TEAMS
Alan Birch discussed the role of an Oncology Drug Access Navigator as well as how the role fits into the healthcare team and what they help patients with. He gave a brief overview and history of the role as well as discussing challenges faced by patients and how National Pharmacare may impact it all...

Drug Discovery 2018
DRUG DISCOVERY 2018
Despite the rapid pace of scientific advances that garner a better understanding of a myriad of diseases on their molecular level, modern drug discovery is a long, complex process. As to be expected, the course of action for researching and developing new medicines is growing in difficulty and lengt...

Neuroscience 2018
NEUROSCIENCE 2018
Our  6th Annual world-renowned Neuroscience virtual conference is now available On Demand! Neuroscience 2018 aims to explore the mechanisms of neural function from the molecular to the network level in health and disease. World-renowned experts and thought leaders discussed the dynamics of brai...

Solving Medical Technology Product Development Issues
SOLVING MEDICAL TECHNOLOGY PRODUCT DEVELOPMENT ISSUES
There is an increasing number of emerging medical technologies (MedTech) which are having a significant effect on the medical equipment and medical device industries. The main principles that come into play when applying these new medical technologies are design for manufacturability, thinking ahead...

Recent Technological Advancements in Medical Communication
RECENT TECHNOLOGICAL ADVANCEMENTS IN MEDICAL COMMUNICATION
Join this webinar for a discussion of the most common medical communications business challenges and potential solutions. This event will also feature a live demonstration of how patient-centric medical communications technology can be leveraged to streamline and optimize medical inquiry fulfillment...

Clinical Supply Planning Optimization
CLINICAL SUPPLY PLANNING OPTIMIZATION
This webinar provides a comprehensive overview of the current supply planning landscape, identifies gaps which are inhibiting supply professionals from optimizing their supply chains and delves into solutions for driving efficiencies from a people, process and technology perspective. Also to be disc...

How to Solve Big Challenges in Small Biotechs Using Big Data Analytics
HOW TO SOLVE BIG CHALLENGES IN SMALL BIOTECHS USING BIG DATA ANALYTICS
Small biotechs are the engine of scientific innovations in the biopharmaceutical industry. However, they are saddled with many of the challenges facing big companies such as data silos and challenges to quick access to information critical to managing their clinical trials. This is manifested by the...

3D Organ-on-a-chip Applications Using the AIM Biotech Chip
3D ORGAN-ON-A-CHIP APPLICATIONS USING THE AIM BIOTECH CHIP
In the vitro 3D cell, culture models have emerged as a bridge between conventional 2D cell culture models and the complex & expensive in vivo animal models. By analyzing and comparing the biological behavior of tissues embedded in 3-dimensional hydrogels, results are significantly different from...

Intellectual Property in biotech: from bioprinting to bedside
INTELLECTUAL PROPERTY IN BIOTECH: FROM BIOPRINTING TO BEDSIDE
TeVido BioDevices uses the innovative process of 3D bioprinting living human cells for use as implants or grafts for use in reconstructive surgery and wound care, for example in post-surgery care for cancer patients. TeVido uses a simple yet sophisticated approach to produce living tissue produ...

Patient-Centric IRT Management for Compassionate Use Studies
PATIENT-CENTRIC IRT MANAGEMENT FOR COMPASSIONATE USE STUDIES
When developing lifesaving medications for patients is at your core, it is essential to streamline the processes of managing the critical clinical supplies and trial data through advanced technology. The pooled clinical supply approach, when coupled with a comprehensive control system, offers unique...

Harmonising drug-target binding data analytics on a single platform
HARMONISING DRUG-TARGET BINDING DATA ANALYTICS ON A SINGLE PLATFORM
In early-stage medicines research, measuring in vitro drug-target interaction characteristics is a critical path activity in selecting therapeutic candidates for progression into pre-clinical models. Technologies and instrumentation used in this space are numerous. Bespoke instrument-specific data a...

High throughput screening for deep mining of antibody repertoires
HIGH THROUGHPUT SCREENING FOR DEEP MINING OF ANTIBODY REPERTOIRES
Antibodies are the key drivers of new drug development based on biologics rather than small molecules. Multiple blockbuster drugs have emerged in this area, many more are in the pipeline. In this webinar, Stefan Moese talks about the implementation of a high throughput screening approach for mining ...

Analytical Chemistry 2018
ANALYTICAL CHEMISTRY 2018
The field of analytical chemistry is focused on advancements in experimental design, chemometrics, and the creation of new analytical instrumentation. Analytical chemistry has broad applications into forensics, environmental testing, pharmacological developments, material science, and engineering.&n...

Fit-for-Future Pharmacovigilance Sourcing Strategies
FIT-FOR-FUTURE PHARMACOVIGILANCE SOURCING STRATEGIES
The challenges and demands of pharmacovigilance in today’s climate has shifted significantly. How do we determine what should and can be sourced differently compared to our traditional models? Offshore-outsourced blended models are becoming increasingly popular. Join this webinar for a discuss...

Nuclear Imaging of CNS Diseases in Rodent Models
NUCLEAR IMAGING OF CNS DISEASES IN RODENT MODELS
Nuclear imaging provides translational and noninvasive in vivo methodology to reliably quantify pathological changes during disease progression and allows evaluation of therapeutic effects of existing or novel drugs against the disease. This webinar showcases new developments of CNS Discovery Servic...

Inhalation Drug Delivery: Considerations for Toxicology and Pharmacology Research
INHALATION DRUG DELIVERY: CONSIDERATIONS FOR TOXICOLOGY AND PHARMACOLOGY RESEARCH
Drug delivery to the lungs in both the clinical and non-clinical setting is a unique combination of formulation, the delivery device and the system/model that the drug is being delivered to. Throughout different stages of drug development, the requirements for inhalation drug delivery change and the...

Getting the Most Out of Interactive Response Technology in Clinical Trial Supply
GETTING THE MOST OUT OF INTERACTIVE RESPONSE TECHNOLOGY IN CLINICAL TRIAL SUPPLY
Increasingly complex, international clinical trials demand a smart, comprehensively planned approach. With the correct interactive response technology (IRT) system in place, you have a powerful tool for accelerating your product’s progress to launch.  While IRT manages patient interaction...

Pediatric Cancer Genomics: Accessing Data, Tools and Visualizations in St. Jude Cloud
PEDIATRIC CANCER GENOMICS: ACCESSING DATA, TOOLS AND VISUALIZATIONS IN ST. JUDE CLOUD
Next-generation genomic sequencing is transforming what is known about pediatric cancer and how we treat patients. But even with new technologies, challenges remain. In the past, the sheer size of genomics data has made sharing across the global scientific community a challenge. St. Jude Cloud is a ...

Better Target Validation for Drug Discovery with CRISPR/Cas9
BETTER TARGET VALIDATION FOR DRUG DISCOVERY WITH CRISPR/CAS9
Better target validation is a key driver of better productivity in drug discovery. The RNA-guided nucleases, exemplified by Cas9, represent a powerful new approach to understanding gene function and, in principle, to reveal the next generation of therapeutic targets. But how well does this technolog...

Transforming translational research: CANscript–A better predictive model for oncology
TRANSFORMING TRANSLATIONAL RESEARCH: CANSCRIPT–A BETTER PREDICTIVE MODEL FOR ONCOLOGY
In this webinar, speaker Mark Paris, Ph.D. discussed a recent study evaluating a cohort of HNSCC patient tumors treated with anti-PD1 using CANscript™. He also is reviewed the results of this study as a means of investigating predictors of clinical response and identifying mechanisms of resist...

Starting a Third Party Analytical Laboratory in the Cannabis Industry
STARTING A THIRD PARTY ANALYTICAL LABORATORY IN THE CANNABIS INDUSTRY
In this webinar, we will explore the challenges and opportunities of starting a third-party testing laboratory in the cannabis industry. Seth Wong, a 15-year seasoned laboratory executive, will walk us through his experience starting a new ISO/IEC 17025 analytical lab on the University of Colorado A...

Proving the Strategic Value of Patients
PROVING THE STRATEGIC VALUE OF PATIENTS
Patient insights aren’t just a ‘nice to have’: they are essential to understanding the space where Pharma’s drugs ‘live’. On the 10th October, Cello Health Insight in association with PMGroup will look at the value of three areas of patient research that provide t...

The mast cell receptor MrgX2 and drug-induced anaphylaxis
THE MAST CELL RECEPTOR MRGX2 AND DRUG-INDUCED ANAPHYLAXIS
Activation of MrgX2, a GPCR expressed on mast cells, leads to degranulation and histamine release. MrgX2 binds promiscuously to basic peptides and small molecules, resulting in acute histamine-like adverse drug reactions, both in man and in mammalian species used in drug toxicology. The goal of this...

Realising the biotech promise: addressing the path to market
REALISING THE BIOTECH PROMISE: ADDRESSING THE PATH TO MARKET
Now more than ever before, Biotech is the engine for innovation in medicine, finding, creating and delivering ground-breaking treatments to patients. The journey from molecule discovery and development through valuation, funding, regulatory and commercialization can be a long and complex road to tra...

Identify and Quantify Individual Host Cell Proteins
IDENTIFY AND QUANTIFY INDIVIDUAL HOST CELL PROTEINS
ELISA is the golden standard for HCP analysis but has some drawbacks. It only provides a single number (ng HCP/mg drug substance) and no information about the specific HCP’s. Here we present an HCP analysis method based on a SWATH LC-MS that provides reproducible identification and absolute qu...

Association of Biotin Ingestion with Performance of Hormone and Nonhormone Assays in Healthy Adults
ASSOCIATION OF BIOTIN INGESTION WITH PERFORMANCE OF HORMONE AND NONHORMONE ASSAYS IN HEALTHY ADULTS
High dose of biotin may cause interference with many routine clinical immunoassays and inaccurate results of some of the tests such as cardiac troponin have serious clinical complications. There is an increasing trend of high dose biotin supplement use in the US population, although the exact preval...

Good culture for your cells - Best practices for preventing contamination
GOOD CULTURE FOR YOUR CELLS - BEST PRACTICES FOR PREVENTING CONTAMINATION
Are ethanol and antibiotics the best measures to prevent microbial contamination? Contamination is an everyday challenge in cell culture labs. Undetected or ignored contamination endanger the reliability and reproducibility of experimental data.  Get to know the most effective methods to detect...

The Future of Marketing in Life Sciences: Is your function fit for purpose?
THE FUTURE OF MARKETING IN LIFE SCIENCES: IS YOUR FUNCTION FIT FOR PURPOSE?
The healthcare landscape is rapidly changing as it responds to a multitude of well-known issues. Coupled with emerging digital technologies, these drivers are shaping the industry, moving it towards a more sophisticated, outcomes-driven model that demands a new approach. The new world emerging is on...

CRISPR 2018
CRISPR 2018
With continued adoption and integration in research labs, CRISPR gene editing has gained importance both as a research tool in drug discovery, screening, and therapeutic development. This inaugural event will bring together thought leaders from academia, trained researcher from clinical laboratories...

Improving hepatocyte activity, pooling and lab efficiency
IMPROVING HEPATOCYTE ACTIVITY, POOLING AND LAB EFFICIENCY
CryostaX® hepatocytes are created using a patented process that produces unique single-donor cell pellets. This format allows for distinct benefits to hepatocyte performance, efficiency in the lab, and test system design, precipitating the potential discontinuation of cryopreserved hepatocytes p...

Quantify Intact Virus Particles More Precisely And Faster Than qPCR
QUANTIFY INTACT VIRUS PARTICLES MORE PRECISELY AND FASTER THAN QPCR
An analytical quality by design (AQbD) approach was embraced for the development of a capillary zone electrophoresis (CZE) method for the quantification of intact virus particles. With CE, the intact adenovirus particles were separated from sample matrix components such as cell debris, residual cell...

Laboratory Animal Sciences 2018
LABORATORY ANIMAL SCIENCES 2018
The 7th annual Laboratory Animal Sciences (LAS) virtual conference is now available on-demand! The LAS Planning Committee, led by Dr. Szczepan Baran, Global Head of Animal Welfare and Compliance Training at Novartis Pharmaceuticals, and composed of more than 20 world-renowned experts, will plan and ...

Using AI and IoT to Accelerate Research
USING AI AND IOT TO ACCELERATE RESEARCH
A serial entrepreneur in sensors, IoT, medical devices, and wearables, Sridhar is founded Elemental Machines with the mission to build products to help science-based companies decipher and understand physical processes from R&D to manufacturing. Previously, Sridhar was a founder of Misfit, maker...

Skin toxicity mechanisms associated with mGluR5 negative allosteric modulators
SKIN TOXICITY MECHANISMS ASSOCIATED WITH MGLUR5 NEGATIVE ALLOSTERIC MODULATORS
Cutaneous reactions represent one of the most common adverse drug effects observed in clinical trials leading to substantial compound attrition. In this webinar, Falgun Shah discussed three negative allosteric modulators of metabotropic glutamate receptors, developed by Pfizer, which recently failed...

Improving Intact Antibody and Plasma Glycoprotein Analysis with Native MS and Parsimonious Charge Deconvolution
IMPROVING INTACT ANTIBODY AND PLASMA GLYCOPROTEIN ANALYSIS WITH NATIVE MS AND PARSIMONIOUS CHARGE DECONVOLUTION
Recent developments in mass spectrometry technology have enabled the analysis of intact native glycoproteins and protein complexes using Orbitrap mass analyzers with extended mass ranges  (EMR). High sensitivity and resolution enable the profiling of critical quality attributes and biosimilarit...

Defects in potassium channels contribute to reduced immune surveillance in cancers
DEFECTS IN POTASSIUM CHANNELS CONTRIBUTE TO REDUCED IMMUNE SURVEILLANCE IN CANCERS
Harnessing the immune system has emerged as a powerful therapeutic strategy in oncology. However, the limited ability of cytotoxic CD8+ T cells to infiltrate solid tumors presents a major roadblock to developing effective immunotherapy. Cytotoxic CD8+ T cells, in fact, have to infiltrate solid tumor...

In vitro phenotypic assays for Parkinson’s disease
IN VITRO PHENOTYPIC ASSAYS FOR PARKINSON’S DISEASE
The discovery and validation of novel targets are essential to fuel a healthy drug pipeline, and in vitro phenotypic assays are instrumental for delivering valid targets and promising lead molecules. View this webinar to learn more about our in vitro assay capabilities performed in clinically releva...

Advanced process development using automated micro bioreactors shortens the timeline
ADVANCED PROCESS DEVELOPMENT USING AUTOMATED MICRO BIOREACTORS SHORTENS THE TIMELINE
In the last eight years, the ambr platform has developed into a significant component of the toolset used by the biopharmaceutical industry for a wide range of upstream activities. The small-scale, high throughput nature of the systems coupled with the associated software functionality enables many ...

Phenotypic assays for CNS disease drug discovery
PHENOTYPIC ASSAYS FOR CNS DISEASE DRUG DISCOVERY
Central nervous system (CNS) disorders constitute a growing unmet medical need, with increasing prevalence of aging-related diseases (Alzheimer’s and Parkinson’s). While classical approaches in cell lines and primary neurons are valuable, (patient-derived) stem cell-based neuronal model ...

High-throughput Single Cell RNA-seq from Flow-Sorted Cells Using a Novel Miniaturized CEL-seq2 Protocol
HIGH-THROUGHPUT SINGLE CELL RNA-SEQ FROM FLOW-SORTED CELLS USING A NOVEL MINIATURIZED CEL-SEQ2 PROTOCOL
Plate-based scRNA-seq approaches are advantageous for the in-depth analysis of rare cell types and subpopulations selected by cell surface markers. This webinar will introduce a high-throughput process for generating sequencing libraries from single cells sorted into 384-well plates. Due to the redu...

Using open science to develop Pediatric Cancer Drugs
USING OPEN SCIENCE TO DEVELOP PEDIATRIC CANCER DRUGS
Childhood brain tumors are genetically distinct from adult cancers and are not a focus area for drug development. M4K Pharma is pioneering a novel open science business model to address these unprecedented “high risk” targets for a fraction of the usual cost. In this webinar, the speaker...

Art Therapy Interventions for Traumatized Children
ART THERAPY INTERVENTIONS FOR TRAUMATIZED CHILDREN
Most clinicians who work with children use art as a way to connect with their young clients, and there has been an increase in referrals for services for children who have experienced significant trauma. This topic will provide clinicians with an introduction to art therapy history and theory, a dis...

Answer the challenges of CDS Data integrity - Sterling Pharma Solutions Ltd
ANSWER THE CHALLENGES OF CDS DATA INTEGRITY - STERLING PHARMA SOLUTIONS LTD
Data integrity continues to be a hot topic for the regulatory agencies in the pharmaceutical industry. In 2012, Sterling Pharma Solutions, embarked on a mission to replace their existing chromatography data systems (CDS). It was important to have one system for the entire company spanning both labor...

Drug-Antibody Ratio (ADC) Calculations Made Easy by CE
DRUG-ANTIBODY RATIO (ADC) CALCULATIONS MADE EASY BY CE
Antibody-drug conjugates are gaining interest as new therapeutic drug targets in the BioPharma Industry. Recent developments in separations technology are enabling scientists to easily calculate antibody drug payloads of both cysteine and lysine conjugates of thermally stressed samples.

Early disease detection performing NMR - Understanding how a better analysis of metabolites in serum and urine can help
EARLY DISEASE DETECTION PERFORMING NMR - UNDERSTANDING HOW A BETTER ANALYSIS OF METABOLITES IN SERUM AND URINE CAN HELP
Quantification in body fluids like plasma/serum and urine is valuable because it provides information on endogenous compounds produced in the body as well as capturing drugs and their metabolites, in addition, lifestyle-based molecules can be recognized, be it from nutritional habits or physical act...

Biomarker endpoints for Parkinson’s disease
BIOMARKER ENDPOINTS FOR PARKINSON’S DISEASE
Therapeutic approaches for Parkinson’s disease are either focused on disease modification (a-synuclein or MPTP models) or symptom management (haloperidol or 6-OHDA models). Our scientists have validated available PD models for changes in fine motor skills, L-dopa-induced dyskinesias, drug-indu...

3D Cell Cultures and Tissue Clearing
3D CELL CULTURES AND TISSUE CLEARING
With the advent of cost-effective culturing approaches, 3D cell culture models (3D-CCMs) have been rapidly adopted for drug discovery since they provide a more physiologically relevant micro-environment; showing improved predictive utility for assessing drug efficacy and/or toxicity when compared to...

Streamlining drug discovery assays for cancer and cardiovascular disease
STREAMLINING DRUG DISCOVERY ASSAYS FOR CANCER AND CARDIOVASCULAR DISEASE
Declining R&D productivity is a key challenge in the pharmaceutical industry today. To increase the success rate of candidate drugs entering the clinical phase, companies must address the early stages of drug discovery. In lead optimization, target-based assays are still the most affordable mean...

Impact of Vicarious Traumatization on Healthcare Workers
IMPACT OF VICARIOUS TRAUMATIZATION ON HEALTHCARE WORKERS
There is a growing healthcare crisis in the ranks of healthcare providers. High demand care areas, higher patient acuities, fewer resources and more work demands deplete care providers of their personal reserves. Unidentified, this problem can manifest as joylessness, hostility, and aggression among...

From Slow Analytics Adoption to Data-Driven Sales Success
FROM SLOW ANALYTICS ADOPTION TO DATA-DRIVEN SALES SUCCESS
What’s the secret to getting widespread analytics adoption across your organization? Using a thoughtful, modern approach. Biotech giant Sanofi Genzyme influenced senior executives, managers, and field sales teams to adopt Qlik® solutions. Watch our Customer Spotlight Webinar to hear their ...

Using Reference Standards to Validate your NGS Oncology Workflow
USING REFERENCE STANDARDS TO VALIDATE YOUR NGS ONCOLOGY WORKFLOW
We are currently at an exciting precipice in clinical oncology management, where an increased rate of biomarker identification is driving the development of new targeted therapies, coupled with advances in sequencing technology capability. In the latest version release of COSMIC (v85) there are now ...

Large-Scale Brain Mapping for Reverse Engineering Brain Function
LARGE-SCALE BRAIN MAPPING FOR REVERSE ENGINEERING BRAIN FUNCTION
The Kasthuri lab is pioneering new techniques for large volume reconstructions of the fine structure of the nervous system – ‘connectomics’. In this webinar, Dr. Kasthuri will describe these developments including large volume automated electron microscopy for mapping neuronal conn...

Tackle biologics QC with Hound and Bouncer
TACKLE BIOLOGICS QC WITH HOUND AND BOUNCER
Particles muck up the quality of a drug and can shut down its production. Hound is the only tool out there that analyzes particles by size and shape then forensically identifies them by their chemical and elemental fingerprints. In minutes, you can pinpoint the culprit, track it back to the source, ...

Step up your biologics stability screening with Hunky
STEP UP YOUR BIOLOGICS STABILITY SCREENING WITH HUNKY
Many methods for studying protein stability and aggregation are qualitative, which can cause uncertainty when moving drug candidates and formulations forward. In contrast, Hunky gives you the Gibbs free energy (ΔG) of a protein, which is a powerful and quantitative indicator of the amount of u...

Advancing precision immunotherapy through next-generation sequencing of T cell receptors: Part I
ADVANCING PRECISION IMMUNOTHERAPY THROUGH NEXT-GENERATION SEQUENCING OF T CELL RECEPTORS: PART I
This webinar will review recent advancements in the application of next-generation sequencing of T cell receptor beta (TCRB) chain repertoires towards predictive and mechanistic biomarker discovery for cancer immunotherapy. Dr. Looney will focus on immunotherapy biomarker applications of a long-ampl...

Precision Medicine 2018
PRECISION MEDICINE 2018
Our 3rd Annual Precision Medicine Virtual Conference is now available On Demand! Precision Medicine 2018 will continue the dialogue and provide updates on new efforts in drug discoveries, developments in FDA regulatory structures, and the integration of genetics on disease progression. Precision Med...

CRISPR for Disease Detection and the Future of Accessible Healthcare
CRISPR FOR DISEASE DETECTION AND THE FUTURE OF ACCESSIBLE HEALTHCARE
This webinar explores the technology behind Mammoth Biosciences’ newly announced CRISPR-powered diagnostics platform, giving insight to CRISPR and how it works for disease detection. In this webinar, Ashley will first give an explanation of what CRISPR does and how it’s been used up unti...

Exon-level array: Bridging the gap between chromosomal microarray and next-gen sequencing
EXON-LEVEL ARRAY: BRIDGING THE GAP BETWEEN CHROMOSOMAL MICROARRAY AND NEXT-GEN SEQUENCING
Current exon-level arrays and NGS techniques for CNV detection are plagued with a high number of false-positive calls and are challenging from a cost perspective when verifying numerous exon aberrations with orthogonal methods. Relevant gene lists continue to grow such that custom del/dup arrays out...

Using bioactivity profiling to support the progression of phenotypic hits
USING BIOACTIVITY PROFILING TO SUPPORT THE PROGRESSION OF PHENOTYPIC HITS
Bioactivity profiling has been traditionally used to assess the selectivity of new drug candidates in the context of target-based approaches, where pharmacological selectivity is a key requirement. Phenotypic screening provides hit molecules where the only initial constraint is activity in a functio...

The Neuroscience of Body Clocks (Online Symposium)
THE NEUROSCIENCE OF BODY CLOCKS (ONLINE SYMPOSIUM)
This online symposium will explore the neuroscience underpinning the daily rhythms of the brain. Specifically, the event will focus on the neurobiology of circadian rhythms, our 24-hour sleep/wake cycle. Leading researchers will discuss their work investigating the neural circuitry that wakes us up ...

Sequence Your Biopharma N-Glycans in as Little as 1 Hour
SEQUENCE YOUR BIOPHARMA N-GLYCANS IN AS LITTLE AS 1 HOUR
If you are working with N-linked carbohydrates of glycoproteins in the biopharmaceutical or biomedical fields, imagine the amount of time you can save with either semi- or fully-automated CE methods providing you information in just 60-120 minutes. Comprehensive analysis of the N-linked carbohydrate...

Automated assessment of Liver and Cardiac toxicities in lead optimisation, using biochemical and human iPS cell assays
AUTOMATED ASSESSMENT OF LIVER AND CARDIAC TOXICITIES IN LEAD OPTIMISATION, USING BIOCHEMICAL AND HUMAN IPS CELL ASSAYS
In this two-part webinar, both automation of P450 (CYP) assays and the automatization of cellular differentiation processes and compound testing using human induced pluripotent stem cells based assays was covered.  Metabolism of drugs is a key factor in compound toxicity, and automated assays w...

How to make digital work in medtech
HOW TO MAKE DIGITAL WORK IN MEDTECH
The rise of mobile devices and apps, not to mention the involvement of non-medical technology players, is creating a wave of irrevocable digital change for medtech.
It’s transforming how the sector reaches and engages with its stakeholders and customers, and in doing so provides vital o...

Investigating the role of microRNAs in pancreatic cancer progression
INVESTIGATING THE ROLE OF MICRORNAS IN PANCREATIC CANCER PROGRESSION
Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease with a 5-year survival rate of approximately 6%. Despite recent efforts in developing novel therapies, chemotherapy remains the standard of care for advanced pancreatic cancer patients. MicroRNAs (miRNAs) are short non-coding RNAs that act ...

CANCER IMMUNOTHERAPY: EXPERIMENTAL MODELS AND APPROACHES
CANCER IMMUNOTHERAPY: EXPERIMENTAL MODELS AND APPROACHES
The mammalian immune system has developed surveillance mechanisms that can detect cancerous cells. However successful tumor cells have evolved strategies to evade detection. Current therapeutic strategies focus on improving cancer cell recognition and tumor elimination. Both immunocompetent and immu...

Diagnostic and Therapeutic Patent and License Strategies
DIAGNOSTIC AND THERAPEUTIC PATENT AND LICENSE STRATEGIES
Dr. Lisa Haile presents this webinar exploring issues and strategies for diagnostic and therapeutic patents and licenses. This webinar will address questions such as: Are diagnostic tests patentable? What are the effects of the Alice ruling and the Myriad Genetics case on patents? What strat...

Raman spectroscopy measurements during Bioprocessing
RAMAN SPECTROSCOPY MEASUREMENTS DURING BIOPROCESSING
Raman spectroscopy has been seen as the spectroscopic tool used in bioprocessing to monitor and control cell metabolism to optimize quality and yield of titer. This is due to Raman’s insensitivity to water and the ability to analyze samples without manipulation. However, there are certain chal...

Development and Manufacturing of Recombinant Nanoparticle Vaccines
DEVELOPMENT AND MANUFACTURING OF RECOMBINANT NANOPARTICLE VACCINES
A recombinant vaccine technology platform based on highly purified, properly-folded protein antigens in stable well-defined Nanoparticles, enabling the efficient and safe manufacture of vaccines against highly pathogenic targets. Nanoparticles are intrinsically immunogenic, producing both durable ne...

Fast and complete cyclic peptide metabolite detection and characterization by LC-MS
FAST AND COMPLETE CYCLIC PEPTIDE METABOLITE DETECTION AND CHARACTERIZATION BY LC-MS
Cyclic peptides have emerged as next-generation therapeutic agents, due to their unique structure and potential biological function. However, the study of cyclic peptide drug metabolism by LC-MS is challenging because these therapeutics typically do not generate high quality and interpretable fragme...

EFIRM Liquid Biopsy (eLB)
EFIRM LIQUID BIOPSY (ELB)
The advent of personalized medicine employing molecularly targeted therapies has markedly changed the treatment of cancer in the past decade. The liquid biopsy is a rapidly emerging field to address this unmet clinical need as diagnostics based on cell-free circulating tumor DNA (ctDNA) can be ...

Optimised genome editing of PSCs enabling efficient production of disease models
OPTIMISED GENOME EDITING OF PSCS ENABLING EFFICIENT PRODUCTION OF DISEASE MODELS
Therapeutic development for human diseases continues to face obstacles, particularly in translating targets or compounds identified by in vitro screening campaigns to valid targets or efficacious and safe compounds once tested in humans. Here we discuss strategies that leverage induced pluripotent s...

Key components of a comprehensive program for the management of single use technologies in Biologics Manufacturing
KEY COMPONENTS OF A COMPREHENSIVE PROGRAM FOR THE MANAGEMENT OF SINGLE USE TECHNOLOGIES IN BIOLOGICS MANUFACTURING
As a result of the increased adoption of single-use technologies (SUTs) in biotech manufacturing, companies need to develop and implement programmatic approaches for the management of these systems under regulatory compliance. This webinar discusses the key aspects of such programs, with emphasis on...

Emerging biomarkers for the diagnosis of cardiac pathologies
EMERGING BIOMARKERS FOR THE DIAGNOSIS OF CARDIAC PATHOLOGIES
According to the World Health Organization (WHO), cardiovascular diseases (CVD’s) are the leading cause of death accounting for more than 17.3M deaths globally. Modern cardiac diagnostics tests and monitoring techniques are providing ever-increasing insight into the health of the human heart. ...

Have it your way – Produce your own enzymes locally and minimize their operational cost
HAVE IT YOUR WAY – PRODUCE YOUR OWN ENZYMES LOCALLY AND MINIMIZE THEIR OPERATIONAL COST
Biorefining processes converting residual biomass into value-added fuels and chemicals are advancing rapidly across the globe. Biochemical biorefineries rely on powerful cellulase enzymes to hydrolyze biomass into sugars, which can then be further converted into the desired end product. These enzyme...

Molecular Diagnostics 2018
MOLECULAR DIAGNOSTICS 2018
Our  3rd Annual Molecular Diagnostics Virtual Conference is now available On Demand! The Molecular Diagnostics Event is the premier venue for scientists, technologists, and professionals to discuss and present the newest advances in molecular diagnostics testing.

Platform tech development for biosimilar upscaling
PLATFORM TECH DEVELOPMENT FOR BIOSIMILAR UPSCALING
Discover strategies to move candidate molecules through the development. Building consistent, straightforward processes with low variability. Exploring the possibility of using single-use, high throughput bioreactors in the upscaling process

When Honey is Not All Honey and Other Tales of Food Adulteration
WHEN HONEY IS NOT ALL HONEY AND OTHER TALES OF FOOD ADULTERATION
There are many analytical techniques available to detect adulteration and authenticity issues. Ion chromatography (IC) is one such technique. After minimal sample preparation, often just dilution and filtration, samples are separated by ion-exchange and detected by suppressed conductivity, amperomet...

The rise of agritech: How green technology can enable more earth-friendly agriculture
THE RISE OF AGRITECH: HOW GREEN TECHNOLOGY CAN ENABLE MORE EARTH-FRIENDLY AGRICULTURE
There is little doubt that agriculture is indispensable for the continued survival of humanity. Technological advances over the centuries have increased productivity and improved food quality. Agricultural chemicals developed in recent decades have brought significant benefits in crop production, su...

Recent USP Changes: Regulatory and Quality Aspects of Sample Preparation
RECENT USP CHANGES: REGULATORY AND QUALITY ASPECTS OF SAMPLE PREPARATION
The United States Pharmacopeia (USP) has recently made revisions which will have a positive impact on the quality of current analytical sample preparation methods. An update to Chapter 841 (Specific Gravity) was published in the March/April 2012 Pharmacopeial Forum 38(2) which states that the use of...

Field-Flow Fractionation 2.0: Obtaining high-resolution distributions of nanoparticle size and zeta potential, with less time, less effort and more confidence
FIELD-FLOW FRACTIONATION 2.0: OBTAINING HIGH-RESOLUTION DISTRIBUTIONS OF NANOPARTICLE SIZE AND ZETA POTENTIAL, WITH LESS TIME, LESS EFFORT AND MORE CONFIDENCE
This webinar will show how complex nanosuspensions, consisting of macromolecules and nanoparticles with sizes 1-1000 nm, can be characterized with high resolution using field-flow fractionation (FFF) coupled to a multi-angle light scattering (MALS) detector. In the life sciences and medicinal fields...

Multiplexed immunofluorescence and digital image analysis for clinical use
MULTIPLEXED IMMUNOFLUORESCENCE AND DIGITAL IMAGE ANALYSIS FOR CLINICAL USE
There is an ever-increasing need to understand the role of the Tumor Microenvironment (TME) in Cancer Immunotherapy. In this webinar, Drs. Lei Tang, Ph.D. and Mehrnoush Khojasteh, Ph.D. of Roche Tissue Diagnostics (Ventana Medical Systems, Inc.), present their work on multiplex immunofluorescence st...

GMOS IN 2018: WHAT
GMOS IN 2018: WHAT'S THE LATEST ON BIOTECH IN OUR FOOD SYSTEMS?
Canada is the fourth largest producer of genetically modified (GM, also called genetically engineered) crops, and now Canadians are the first in the world to eat a genetically modified fish. What GM foods are we eating, and what’s next? What can we already conclude about the impacts and risks ...

Quantitation and profiling metabolomics and translation to clinical analysis
QUANTITATION AND PROFILING METABOLOMICS AND TRANSLATION TO CLINICAL ANALYSIS
Measurement of these metabolites represents the digital readout of health.  A key aspect of metabolomics is the utilization of high resolution mass spectrometric approaches to detect and identify metabolites from biological fluids and tissues.  The use of multi-analyte analyses as well as ...

Soft Tissue Cancer & IHC
SOFT TISSUE CANCER & IHC
Soft tissue tumors are a broad group of neoplasms that involve the connective tissue of the body. Each year, over 13,000 people in the US are diagnosed with soft tissue sarcomas and over 5,000 people succumb to the malignancy. Because soft tissue sarcomas are very ambiguous and amorphous, many time ...

The Changing Landscape of Real-World Evidence 
and its Impact on Clinical Research
THE CHANGING LANDSCAPE OF REAL-WORLD EVIDENCE AND ITS IMPACT ON CLINICAL RESEARCH
Researchers are encumbered with a plethora of disparate data and analytic tools. These assets pose several challenges which need to be overcome to ensure they satisfy their intended purpose. Users’ expectations are evolving around implementation effort, access, usability and long-term viabilit...

Addressing the challenges of bioconjugation for improved crosslinking and modification
ADDRESSING THE CHALLENGES OF BIOCONJUGATION FOR IMPROVED CROSSLINKING AND MODIFICATION
Bioconjugation is a critical technique for creating many of the key reagents used in research and commercial applications.  This webinar will cover in great detail the major reactions used to form bioconjugates as well as the functional groups which react with them.Learn about the major reactiv...

Diet and gene interactions in the control of central cell metabolism
DIET AND GENE INTERACTIONS IN THE CONTROL OF CENTRAL CELL METABOLISM
In this webinar I will expand upon the link between broccoli bioactives and metabolic homeostasis, highlight the potential role of RNA turnover in metabolic control, and offer insights into the potential implications for the dietary prevention of disease.

Feeding the Next 3 Billion: Biotech and the Future of Food
FEEDING THE NEXT 3 BILLION: BIOTECH AND THE FUTURE OF FOOD
Learn about the powerful opportunities biotechnology is creating within the 15 trillion dollar protein and meat markets..With a rapidly growing global population, our world is surpassing its natural carrying capacity, which begs the critical question: how will we feed the next 3 billion people born ...

Overcoming challenges with the supply of plasmid DNA & other raw materials for gene therapy manufacture
OVERCOMING CHALLENGES WITH THE SUPPLY OF PLASMID DNA & OTHER RAW MATERIALS FOR GENE THERAPY MANUFACTURE
Providing solutions to the manufacturing challenges of gene and cell therapy has never been so important. Successes in gene therapy are taking center stage and we are seeing a new dawn in terms of commercialization. Pricing and reimbursement often take the headlines, but the challenges of manufactur...

Long-Term Live Cell Imaging for High-Content Applications
LONG-TERM LIVE CELL IMAGING FOR HIGH-CONTENT APPLICATIONS
This webinar will detail new developments in image acquisition that combine live cell incubation and imaging with high-content screening approaches. Additionally particular focus on the challenges of storing, processing and analyzing high-content live cell imaging will be discussed.

Taxonomic profiling using shotgun metagenome data
TAXONOMIC PROFILING USING SHOTGUN METAGENOME DATA
In this webinar, we will introduce the latest workflows optimized for shotgun metagenome analysis, which we released with the most recent version of Microbial Genomics Pro Suite our comprehensive, user-friendly and scalable NGS data analysis platform for microbial genomics.The webinar focuses on how...

Analysis and interpretation of cell free DNA
ANALYSIS AND INTERPRETATION OF CELL FREE DNA
Identification and monitoring of cancer mutations of circulating cell-free DNA (cfDNA) is a key application in liquid biopsy. In the webinar series, we discuss various new technologies and present a complete sample to insight workflow for cfDNA mutation analysis. In this webinar, we show how mutatio...

Biologics on the Horizon: Forecasting New Development Opportunities for Pharma Companies
BIOLOGICS ON THE HORIZON: FORECASTING NEW DEVELOPMENT OPPORTUNITIES FOR PHARMA COMPANIES
Biologics is expected to grow into a $400 billion industry by 2025. And with that come many challenges and opportunities for an industry whose very nature is already complex. This webinar explores key takeaways from a recent BioPharma Dive survey that looked into what roles CROs, CMOs and CDMOs are ...

Webinar: Real-time Live-Cell Analysis for Immunologists
WEBINAR: REAL-TIME LIVE-CELL ANALYSIS FOR IMMUNOLOGISTS
The most common in vitro methods for immunologists to analyze cells of the immune system are flow cytometry, PCR and various forms of ELISA. Together, these enable quantification of different cell populations at the molecular and functional level (‘immuno-phenotyping’) and measurement of...

Advanced 3D cell models for cancer biology using real time live-cell analysis
ADVANCED 3D CELL MODELS FOR CANCER BIOLOGY USING REAL TIME LIVE-CELL ANALYSIS
In this webinar, we describe integrated protocols and live-cell analysis solutions for different 3D tumor models, ranging from simple mono-culture single spheroid assays through to multi-spheroid tumor/fibroblast and tumor/immune cell co-cultures in a Matrigel biomatrix.Learn how to:Automatically ac...

The Advent of Biosimilars in Oncology: Planning Proactively for Change
THE ADVENT OF BIOSIMILARS IN ONCOLOGY: PLANNING PROACTIVELY FOR CHANGE
With several oncology biosimilars expected to hit the U.S. market in the next few years, pharmaceutical drug manufacturers need clear insight into stakeholder perceptions and key drivers of adoption in order to thrive in a crowded and complex marketplace.During this webinar, ZS and industry experts ...

Maximizing the Precious Samples in your Biorepository: How to Create Renewable Resources
MAXIMIZING THE PRECIOUS SAMPLES IN YOUR BIOREPOSITORY: HOW TO CREATE RENEWABLE RESOURCES
Biorepositories are rapidly becoming a critical resource in both basic and clinical science programs. The organized collection, processing, and distribution of biological materials is not only growing in the form of centralized biorepositories but also evolving as an important component in individua...

Smartlab Global Academy: Integrated Informatics for Biologics Discovery
SMARTLAB GLOBAL ACADEMY: INTEGRATED INFORMATICS FOR BIOLOGICS DISCOVERY
Pharma and biotechs have greatly increased investments into the development of a wide variety of therapeutic biologics.But in many organizations, the informatics systems that handle biologics lag behind today's requirements. As a result scientists are over reliant on ad-hoc solutions like Excel,...

Increase Bio-Process Yield by Capturing Real-Time Data
INCREASE BIO-PROCESS YIELD BY CAPTURING REAL-TIME DATA
On-line parameters like pH and dissolved oxygen are commonly used to optimize process yield. Further optimization is now possible with a new breed of sensors for on-line measurement of viable and total cell density.In this 45 minute webinar you will:Learn about the impact of continuous, in-situ cell...

THE HUMAN MICROBIOME: IMPACT ON HEALTH AND DISEASE
THE HUMAN MICROBIOME: IMPACT ON HEALTH AND DISEASE
Join Dr. George Weinstock, expert on the human microbiome, as he discusses current research demonstrating the impact of the human microbiome on health and disease.The human microbiome comprises all of the microorganisms living within the human body. This diverse collection of bacteria, viruses, fung...

Fundamentals of RNAi tools and delivery technologies
FUNDAMENTALS OF RNAI TOOLS AND DELIVERY TECHNOLOGIES
RNA interference (RNAi) is still the best way to effectively knock down gene expression to study protein function in a wide range of cell types. Prior to genome editing utilizing CRISPR or TAL technology, RNAi enabled researchers to discover and validate desired phenotypes effectively and with less ...

The Human Microbiome: lessons and challenges in deciphering the microbiota in health and disease
THE HUMAN MICROBIOME: LESSONS AND CHALLENGES IN DECIPHERING THE MICROBIOTA IN HEALTH AND DISEASE
This webinar will present the progress made in metagenomics and the use of largely unassembled sequences in constructing the microbial communities forming the human microbiome. The knowledge assembled from microbial whole genome sequences, and the metabolic traits of the human flora are perhaps the ...

Developing Predictive Liver Models from Pluripotent Stem Cells
DEVELOPING PREDICTIVE LIVER MODELS FROM PLURIPOTENT STEM CELLS
The development of renewable human liver models, from genetically defined origins, is likely to be a game-changing addition to the field of Predictive Toxicology. However, for these models to have significant impact they must be stable in character and capable of manufacture at scale.For this reason...

Deriving Deeper Biological Insight & Improving Productivity in Immune-Cell Biology
DERIVING DEEPER BIOLOGICAL INSIGHT & IMPROVING PRODUCTIVITY IN IMMUNE-CELL BIOLOGY
The most common in vitro methods for immunologists to analyze cells of the immune system are flow cytometry, PCR and various forms of ELISA. Together, these enable quantification of different cell populations at the molecular and functional level (‘immuno-phenotyping’) and measurement of...

Designing the Next Phase in Genome Editing: Advanced CRISPR Applications
DESIGNING THE NEXT PHASE IN GENOME EDITING: ADVANCED CRISPR APPLICATIONS
CRISPR Cas9 nucleases have revolutionized the field of genome editing enabling unprecedented efficiency of gene targeting in a vast array of cell types and organisms. Even with such powerful technology at hand, researchers who are new to the field may find genome modification to be challenging and t...

Genetic Alteration Cell Panels : Tools for High Throughput In Vitro Screening
GENETIC ALTERATION CELL PANELS : TOOLS FOR HIGH THROUGHPUT IN VITRO SCREENING
Extensive genomic sequencing efforts in recent years have provided detailed profiles of the somatic gene mutations that occur in a wide range of human cancers. In order to facilitate basic and translational cancer research, ATCC has designed and validated a number of genetic alteration cell panels t...

The Neuroscience of Body Clocks : The genes, cells and circuits of sleep/wake cycles
THE NEUROSCIENCE OF BODY CLOCKS : THE GENES, CELLS AND CIRCUITS OF SLEEP/WAKE CYCLES
Leading researchers will discuss their work investigating the neural circuitry that wakes us up in the morning and puts us to sleep at night. A cycle that is fundamental to health, well-being and survival. The science discussed at this virtual event will explore circadian rhythms from molecules to b...

Process analytical Technology for Upstream Bioprocessing
PROCESS ANALYTICAL TECHNOLOGY FOR UPSTREAM BIOPROCESSING
In commercial cell culture bioprocessing, consistent high quality protein is a fundamental goal that is typically accomplished during development through product and process engineering of bioreactor parameters. The FDA’s Center for Drug Evaluation and Research (CDER)’s Office of Biotech...

Accelerating Method Transfer: Effective Automation of Biological Assays
ACCELERATING METHOD TRANSFER: EFFECTIVE AUTOMATION OF BIOLOGICAL ASSAYS
Bioassay automation offers ergonomic relief for scientists, consistent method execution, increased throughput, and reduced full-time equivalent expenditure. Importantly, successful automation programs allow unparalleled efficiency in method transfer to receiving laboratories. Many factors are critic...

Emerging Applications of Silver Nanoparticles in Biotechnology
EMERGING APPLICATIONS OF SILVER NANOPARTICLES IN BIOTECHNOLOGY
Silver nanoparticles have extraordinary properties at the nanoscale, which are enabling a wave of innovative commercial products. Many of these new applications are in the field of bionanotechnology where the strong interaction between silver nanoparticles and specific wavelengths of light is utiliz...

Win More Biologics Development Battles with Early Stability Analysis
WIN MORE BIOLOGICS DEVELOPMENT BATTLES WITH EARLY STABILITY ANALYSIS
Biophysical and chemical properties are critical factors that can dictate success or failure in the development of therapeutic antibodies. These attributes and all the functional characteristics of antibodies depend on amino acid sequence, post-translational modifications, and the solution environme...

High-Resolution SPR Surrogate Potency Assay to Facilitate Comparability and Biosimilar Studies
HIGH-RESOLUTION SPR SURROGATE POTENCY ASSAY TO FACILITATE COMPARABILITY AND BIOSIMILAR STUDIES
Learn how SPR can measure not only antibody-target binding but also antibody interactions with Fcy or FcRn receptors .Discover ways that Biacore assays can be simplified and used as surrogate potency assays to ensure comparability and product consistency.See how calibration-free concentration analys...

Multiplex Immunofluorescence Profiling of Tumor Biopsies Using UltraPlex mxIF Technology
MULTIPLEX IMMUNOFLUORESCENCE PROFILING OF TUMOR BIOPSIES USING ULTRAPLEX MXIF TECHNOLOGY
An unmet need in tissue diagnostics is the ability to simultaneously detect three or more markers on a single tissue specimen, i.e. multiplexing.   Unlike other immunoassays, i.e. flow cytometry, ELISA and bead assays, which solely quantify the biomarker in a sample, a multiplex immunoassa...

Investigating DNA repair mechanisms in hypoxic brain tumours and the link to treatment resistance
INVESTIGATING DNA REPAIR MECHANISMS IN HYPOXIC BRAIN TUMOURS AND THE LINK TO TREATMENT RESISTANCE
Glioblastoma (GBM) and Medulloblastoma (MB) are the most common adult and paediatric brain tumours, both of which can have devastating consequences. Patients diagnosed with GBM have a life expectancy of around 15 months, whereas, for MB, the survival rate is higher. However, commonly used treatments...

Rapid and accurate high-throughput in vitro prediction of nephrotoxicity in humans with ProxTox-HTS
RAPID AND ACCURATE HIGH-THROUGHPUT IN VITRO PREDICTION OF NEPHROTOXICITY IN HUMANS WITH PROXTOX-HTS
The human kidney can be damaged by a wide range of xenobiotics, such as industrial chemicals, environmental toxicants and drugs. Major targets for compound-induced damage are renal proximal tubule cells (PTCs) due to their role in compound transport, metabolism and clearance. ProxTox-HTS is the firs...

Understanding the biological machinery by cryogenic TEM imaging and structure determination
UNDERSTANDING THE BIOLOGICAL MACHINERY BY CRYOGENIC TEM IMAGING AND STRUCTURE DETERMINATION
Life is composed of four fundamental building blocks: lipids, sugars, nucleic acids, and amino acids. These basic building blocks polymerize and assembly into the living world around us. Historically, understanding how this organic chemistry creates the machinery of life required crystallization and...

Advances in viral vector technology: Anc-AAV & evolutionary guided vector design
ADVANCES IN VIRAL VECTOR TECHNOLOGY: ANC-AAV & EVOLUTIONARY GUIDED VECTOR DESIGN
Gene therapy is a potent modality with demonstrated ability to intervene in diseases of unmet medical need. Its safety and efficacy is often governed by the vector system used. Adeno-associated viral vectors (AAV) have shown great promise for sustained expression of a therapeutic gene in vivo.This w...

Biosimilar Development: Lessons Learned from Early Clinical Studies
BIOSIMILAR DEVELOPMENT: LESSONS LEARNED FROM EARLY CLINICAL STUDIES
The success of early clinical studies comparing a biosimilar drug candidate with the innovator compound is dependent on the similarity of the products themselves, as well as on the quality of the bioanalytical assay method and the design and conduct of early PK/PD studies. Based on our experience, g...

Cardiovascular Safety in Biopharmaceutical Product Development – From QT Prolongation and Beyond
CARDIOVASCULAR SAFETY IN BIOPHARMACEUTICAL PRODUCT DEVELOPMENT – FROM QT PROLONGATION AND BEYOND
The cardiac safety ECG environment continues to mature and expand based on scientific advancements and understanding of pathways and systems associated with generating cardiac risk. The most recent ICH-E14 Q&A, and the ensuing cardiac safety conferences and industry meetings, have highlighted th...

Biologics in Dermatology: Considerations for Patients and Clinical Trials
BIOLOGICS IN DERMATOLOGY: CONSIDERATIONS FOR PATIENTS AND CLINICAL TRIALS
Traditional dermatologic treatment methods, including topicals, phototherapies and traditional drugs, do not always fully meet the needs of patients with the most severe disease presentation. For these patients, biologics present alternative treatment options and hope for new avenues to recovery. Th...

Genomic support for target selection and validation in drug development: design of a new genotyping array
GENOMIC SUPPORT FOR TARGET SELECTION AND VALIDATION IN DRUG DEVELOPMENT: DESIGN OF A NEW GENOTYPING ARRAY
Drug target validation is a major obstacle to drug development leading to high rates of late-stage failure because the pivotal study in drug development – the randomised trial – occurs at the end of the development pipeline.Genetic studies using the principle of Mendelian randomisation r...

New strategy to identify small molecule therapies
NEW STRATEGY TO IDENTIFY SMALL MOLECULE THERAPIES
This webinar details a successful new strategy to identify small molecule therapies to mitigate the hearing loss associated with these mutations, highlighting the promise of this discovery approach in the quest for drugs to treat other protein-destabilising monogenic disorders. Funded by the Usher I...

Primary Cell Systems: Offerings and Applications from basic biology and tissue modeling to compound screening
PRIMARY CELL SYSTEMS: OFFERINGS AND APPLICATIONS FROM BASIC BIOLOGY AND TISSUE MODELING TO COMPOUND SCREENING
Primary cells are derived from various tissues typically via dissection, enzymatic dissociation, and subsequent culture in media specifically designed to support expansion of defined cell types.   Following expansion, primary cells largely retain the characteristics of the tissue from whic...

Engineering Yeast for Industrial Biotechnology
ENGINEERING YEAST FOR INDUSTRIAL BIOTECHNOLOGY
The webinar was of particular relevance to industry scientists interested in developing new strains, products and processes, but was useful for anybody fascinated by the potential of yeast in biotechnology.60 people from around the world attended the webinar. There was a mix of industry (SMEs and MN...

Recent Advances in Multiple Myeloma and Their Implications for Future Development
RECENT ADVANCES IN MULTIPLE MYELOMA AND THEIR IMPLICATIONS FOR FUTURE DEVELOPMENT
The webinar discussion will focus on important topics for Hemato-Oncology commercial and clinical development teams, including how treatment strategies in Multiple Myeloma are evolving, and why recent advances in the field will shape strategies for differentiation and value.Join us and learn more ab...

Cell culture media for cell manufacturing
CELL CULTURE MEDIA FOR CELL MANUFACTURING
Cell culture media strongly determine performance and safety of manufactured cell products as well as cell processing consistency.Hence, choosing a medium that supports translation from basic research to clinical applications is essential. In this webinar, we will discuss which criteria are key for ...

Expression vectors: how to choose, or customize, vectors for gene & protein expression
EXPRESSION VECTORS: HOW TO CHOOSE, OR CUSTOMIZE, VECTORS FOR GENE & PROTEIN EXPRESSION
Do you make new DNA constructs only using the old expression vectors you're most familiar with? This webinar will help you make your experimental design more efficient and powerful by learning how to select or design an expression vector that is optimized for your experiments. We will walk throu...

New Probes and Sensors in Neurobiology
NEW PROBES AND SENSORS IN NEUROBIOLOGY
Current efforts in neuroscience are being devoted to mapping activity in defined cells and to developing tools and methods that allow the interrogation of specific circuits in great detail. In this webinar, we will hear from young scientists who will present a snapshot of different techniques and th...

Reflexion Health working on back and spine surgery indication for rehab remote monitoring
REFLEXION HEALTH WORKING ON BACK AND SPINE SURGERY INDICATION FOR REHAB REMOTE MONITORING
Reflexion Health has updated its FDA-cleared procedure prep and recovery product for hip and knee replacement as it works on a new indication designed for back, spine and shoulder surgery. The updates include new additions geared for patients and on the provider side. The remote monitoring business ...

Deep Learning for Biotechnology on Qubole
DEEP LEARNING FOR BIOTECHNOLOGY ON QUBOLE
In the biological sciences, hypothesis-driven experiments and bottom-up design experiments rely on predicting what will happen with new cells and molecules. Machine learning excels at prediction and has become more democratized, making it an important component in the biotech toolkit. We use Merck&#...

Leveraging Real World Data to Streamline Clinical Trials
LEVERAGING REAL WORLD DATA TO STREAMLINE CLINICAL TRIALS
Industry is encumbered with lengthy drug development timelines and high costs. These challenges are correlated with the difficulty to recruit appropriate patient populations for clinical trials. Join this session to learn how real world data is transforming the way biopharma, CROs and study sites na...

Thiol-linked alkylation for the metabolic sequencing of RNA
THIOL-LINKED ALKYLATION FOR THE METABOLIC SEQUENCING OF RNA
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady state but obscures the intracellular dynamics of RNA transcription, processing and decay. We developed thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAMse...

Serialization & Data Management: Industry Standards In Master Data Management And How To Best Implement Them
SERIALIZATION & DATA MANAGEMENT: INDUSTRY STANDARDS IN MASTER DATA MANAGEMENT AND HOW TO BEST IMPLEMENT THEM
This webinar is one of two webinars about data management requirements deriving from Serialization with focus on Europe and the United States. The webinars are structured around the theme "data in - data on - data out". This webinar is hosted by industry experts Heidi Vanheerwyngshels (Vid...

The 6 Most Common Problems in FDA Software Validation & Verification
THE 6 MOST COMMON PROBLEMS IN FDA SOFTWARE VALIDATION & VERIFICATION
This FDA Software Validation and Verification training/webinar will review the validation planning process with particular emphasis on avoiding six common pitfalls.

SmartLab Global Academy: The Path to Digital Transformation in Life Sciences
SMARTLAB GLOBAL ACADEMY: THE PATH TO DIGITAL TRANSFORMATION IN LIFE SCIENCES
For pharma and biotech, in which data is the most valuable asset, industry analysts agree that digital transformation presents an opportunity to realize unprecedented productivity gains and competitive advantage.

Rethinking Collaboration in Biologics Discovery
RETHINKING COLLABORATION IN BIOLOGICS DISCOVERY
Today’s biotherapeutics research labs need to be able to successfully work with big data (genomics), public data, and various classes of experimental data to effectively operate in the modern world of biologics R&D. This environment only becomes more complex as many organisations are explo...

Limitations and Benefits of Immunofixation
LIMITATIONS AND BENEFITS OF IMMUNOFIXATION
Monoclonal Gammopathies (MG) are characterized by chromosomal aberration of B-cells or plasma cells resulting in benign or malignant proliferation of the affected clone. The product of such clone, a monoclonal protein, is an essential laboratory marker for the detection, identification and classific...

The importance of raising patient awareness
THE IMPORTANCE OF RAISING PATIENT AWARENESS
Although telehealth has been around for years, patients aren't always aware of the array of virtual services available to them. In short: It's up to health systems to make telehealth capabilities known. A number of health systems are no longer looking to merely implement telehealth solutions...

Engineered Viruses as Precision Cancer Therapeutics
ENGINEERED VIRUSES AS PRECISION CANCER THERAPEUTICS
Oncolytic virotherapy, the use of viral vectors to treat cancer, holds huge promise. Viruses are natural DNA delivery vehicles evolved to target specific tissues and transform them. Oncolytic virotherapies harness these abilities for therapeutic rather than pathological results. By engineering the v...

Principles of Biomanufacturing: Using Biotechnology to Manufacture Medicines
PRINCIPLES OF BIOMANUFACTURING: USING BIOTECHNOLOGY TO MANUFACTURE MEDICINES
The manufacturing of successful biologic medicines requires strong cross-functional collaboration. Yet many organizations are heavily siloed and fragmented communication across divisions can slow progress towards producing medicines for patients. Could your organization be working more effectively a...

ER and Urgent Care Mistakes to Avoid
ER AND URGENT CARE MISTAKES TO AVOID
During the holiday season, approximately 15,000 people will visit the Emergency Room or an urgent care clinic after being injured while putting up holiday decorations. Still others will become ill while visiting relatives and need to see a doctor. In this November 2016 webinar, Dr. Eric Bricker will...

Accurate Antibody Molecular Modeling Enables Epitope Determination
ACCURATE ANTIBODY MOLECULAR MODELING ENABLES EPITOPE DETERMINATION
The importance of antibody discovery and engineering for pharmaceutical development has grown significantly over the past two decades. During the past few years, modeling tools for antibody discovery and engineering have been developed, taking advantage of the structural knowledge existing in the pr...

Multiparameter Cell Cycle Analysis
MULTIPARAMETER CELL CYCLE ANALYSIS
Most cell cycle assays amount to counting cells and/or measuring DNA content and deconvolving the resulting histogram into G1, S, G2+M, or G1, S, G2, and M.  Considerable effort has been put to correlating DNA content with RNA, protein, or specific epitopes to determine or discover additional c...

Defining and Managing Protocol Deviation/Violation/Exception
DEFINING AND MANAGING PROTOCOL DEVIATION/VIOLATION/EXCEPTION
As the purpose of a clinical trial is to determine safety and effectiveness of a treatment, it is imperative that the rules of the trial be followed exactly. If there are Instances of “Protocol Not Followed” (PNF), that could result in a failure to determine safety and effectiveness. Tha...

Understanding Disinfection and Cleanroom Cleaning in a FDA Regulated Environment
UNDERSTANDING DISINFECTION AND CLEANROOM CLEANING IN A FDA REGULATED ENVIRONMENT
This 90-minute webinar on Disinfection and Cleanroom Cleaning will cover effective ways to rotate disinfectants, most current industry methods for applying disinfectants and effective methods for controlling residues.

NCBA, Cattle Genetics Experts Team Up For 2018
NCBA, CATTLE GENETICS EXPERTS TEAM UP FOR 2018
Cattle genetics will be the focus of a new set of webinars to help cattlemen and women better use the tool in their operations. The National Cattlemen’s Beef Association is teaming up with six genetics specialists from across the country to offer the Titled “Fake News: EPDs Don’t W...

The Path to Digital Transformation in Life Sciences
THE PATH TO DIGITAL TRANSFORMATION IN LIFE SCIENCES
For pharma and biotech, in which data is the most valuable asset, industry analysts agree that digital transformation presents an opportunity to realize unprecedented productivity gains and competitive advantage. For many labs, the real question is where do we start? The launch pad for digital trans...

Managing pesticide resistance in vegetable crops with Dr Paul Horne (webinar recording)
MANAGING PESTICIDE RESISTANCE IN VEGETABLE CROPS WITH DR PAUL HORNE (WEBINAR RECORDING)
Pesticide resistance is an ongoing concern for the vegetable industry. If you missed this webinar on 20 October 2016, listen to the recording with expert practitioners Dr Paul Horne and Jessica Page from IPM Technologies and Carl Larsen, RMCG to find out more about how resistance arises, developing ...

CRISPRs: Ushering in a New Age of Gene Editing
CRISPRS: USHERING IN A NEW AGE OF GENE EDITING
CRISPRs, which were first described in E. coli in 1987, have since seized the attention of the global biotechnology community. Along with CRISPR-associated (Cas) proteins, these Clustered Regularly Interspaced Short Palindromic Repeats originally arose as a bacterial defense system again bacteriopha...

Micro-Flow Imaging as a Tool for Biopharmaceutical Particle Analysis
MICRO-FLOW IMAGING AS A TOOL FOR BIOPHARMACEUTICAL PARTICLE ANALYSIS
The size of poly(lactic-co-glycolic) acid (PLGA) microparticles is of critical importance for polymer degradation and drug release rates. Current methods for the characterization of PLGA microparticle size provide only limited or no quantitative information or may overestimate size due to the presen...

The Advantages of ExVive 3D Bioprinted Liver Tissue in Capturing the Complex Cellular Events of Monocrotaline-induced Liver Injury
THE ADVANTAGES OF EXVIVE 3D BIOPRINTED LIVER TISSUE IN CAPTURING THE COMPLEX CELLULAR EVENTS OF MONOCROTALINE-INDUCED LIVER INJURY
In the study, which will be discussed in this webinar, we evaluated the effects of MCT in 3D-bioprinted human liver tissue comprising of primary hepatocytes, hepatic stellate cells, and endothelial cells (ExVive™ Human Liver Tissue; Organovo, San Diego CA).The bioprinted tissues were treated w...

Webinar: Production and Sterilization of Biopharmaceutical Nanoemulsions using Filtration
WEBINAR: PRODUCTION AND STERILIZATION OF BIOPHARMACEUTICAL NANOEMULSIONS USING FILTRATION
In this webinar, learn how Microfluidics and Pall collaborated to develop a filtration-based alternative to terminal sterilization for a squalane emulsion. We present the process of development for producing pharmaceutical nanoemulsions and give an insight into the unique advantages of using the Mic...

Antimicrobial Use and Resistance in Beef Cattle (BCRC webinar recording)
ANTIMICROBIAL USE AND RESISTANCE IN BEEF CATTLE (BCRC WEBINAR RECORDING)
They are most commonly used to prevent or treat diseases and infections due to microorganisms, such as bacteria (antibacterial), fungi (antifungal), viruses (antiviral), and protozoa (antiprotozoal).Thus, all antibiotics are antimicrobials, but not all antimicrobials are antibiotics

WEBINAR: What Is a Biosimilar? The Current Biologics and Biosimilars Landscape in Canada
WEBINAR: WHAT IS A BIOSIMILAR? THE CURRENT BIOLOGICS AND BIOSIMILARS LANDSCAPE IN CANADA
Biologic cancer treatments have become incredibly important in oncology, but they can be expensive. Biosimilars are molecules manufactured to replicate the effects of biologics.

Facilitating Drug Discovery with HDX-Mass Spectrometry
FACILITATING DRUG DISCOVERY WITH HDX-MASS SPECTROMETRY
GEN webinar hosted live on December 2, 2015. Dr. Ganesh Anand from the National University of SIngapore and Ms. Kai Zhang from the Lilly Biotechnology Center discuss their experiences using HDX-MS.

Successful Implementation of Automation in Single-Use Bioprocessing
SUCCESSFUL IMPLEMENTATION OF AUTOMATION IN SINGLE-USE BIOPROCESSING
Single-use bioprocess technology has become near ubiquitous within biologics manufacturing facilities. Benefits such as the avoidance of product cross contamination, flexibility process configurations and reduced capital expenditure requirements are especially attractive to contract manufacturing or...

Webinar: Building Better Therapeutics with Metabolomics
WEBINAR: BUILDING BETTER THERAPEUTICS WITH METABOLOMICS
In this webinar, we explain how the use of metabolomics in pharmaceutical R&D is shifting from pre-clinical use to translational science and clinical development. Following a brief primer on the fundamentals of metabolomics, we detail the key reasons behind the shift to the clinic.

LTS Webinar “BigData, Biotechnology, and the Future” with Ricardo Godinez
LTS WEBINAR “BIGDATA, BIOTECHNOLOGY, AND THE FUTURE” WITH RICARDO GODINEZ
Ricardo describes some of the main challenges and opportunities in biotechnology derived from our recent capacity to decode massive amounts of genomic information and the main challenges and solutions to analyze, transfer or assemble or visualize genomic information.

Postgraduate Webinar Series - Plant Biotechnology
POSTGRADUATE WEBINAR SERIES - PLANT BIOTECHNOLOGY
This webinar will provide information about the Plant Biotechnology program as well as insight from an industry representative.

[Webinar] Gene Therapy for Duchenne - August 2017
[WEBINAR] GENE THERAPY FOR DUCHENNE - AUGUST 2017
With trials in gene therapy on the horizon, and terms like "cassette", "construct", "promoter", and "transduce" being thrown around, PPMD wants to ensure that you, our Duchenne Community, has all the knowledge you need to navigate the world of gene therapy.

AllCells Webinar Series: Leuko Pak 101 & Leukapheresis Products
ALLCELLS WEBINAR SERIES: LEUKO PAK 101 & LEUKAPHERESIS PRODUCTS
The biotechnology and pharmaceutical industry is continuing to implement more primary cell based assays in drug discovery due to their biological relevance and there is increased interest in cells of hematopoietic and immunological origin.

Webinar | Biosimilars 101
WEBINAR | BIOSIMILARS 101
This year the FDA approved the first biosimilar drug under the Biologics Price Competition and Innovation Act of 2009 (BPCIA) and the courts have recently rendered some important statutory interpretations. This represents the dawn of a new era in the approval and marketing of biologic products.

New Intrinsically Enteric Capsule Technology for Pharmaceutical Drug Development
NEW INTRINSICALLY ENTERIC CAPSULE TECHNOLOGY FOR PHARMACEUTICAL DRUG DEVELOPMENT
Finding more efficient ways to target drug delivery to the small intestine and provide effective enteric protection for heat or acid-sensitive and/or gastric-irritating drugs are significant challenges for the pharmaceutical industry.

Bioenergy in the CPP Webinar: The Legal Landscape
BIOENERGY IN THE CPP WEBINAR: THE LEGAL LANDSCAPE
The Clean Power Plan (CPP) was announced by President Obama and the EPA in August 2015 and provides the first-ever national standards that address carbon pollution from power plants. The final rule takes into account over 4.3 million stakeholder and public comments to ease its implementation, with i...

Monitoring Product Attributes in Biopharmaceutical Development and QC with LC/HRMS
MONITORING PRODUCT ATTRIBUTES IN BIOPHARMACEUTICAL DEVELOPMENT AND QC WITH LC/HRMS
Across biopharmaceutical development, LC-MS has been a foundational technology for the discovery and characterization of biotherapeutic attributes—including post-translational modifications such as glycosylation, oxidation, and deamidation, as well as process impurities such as host cell prote...

 Harnessing Emerging Technologies to Obtain the Best Chemical Information from Pharmaceutical Products
HARNESSING EMERGING TECHNOLOGIES TO OBTAIN THE BEST CHEMICAL INFORMATION FROM PHARMACEUTICAL PRODUCTS
Extraneous material, such as micro-particles, found in the manufacturing stream of biopharmaceuticals must be identified and the root cause must be determined to take corrective actions. Biopharmaceuticals differ significantly from conventional pharmaceutics in manufacturing and delivery.

HORIBA Webinar - Improve Your Monoclonal Antibodies Analysis
HORIBA WEBINAR - IMPROVE YOUR MONOCLONAL ANTIBODIES ANALYSIS
This Webinar demonstrates the use of the HORIBA HPCE-512 Capillary Electrophoresis platform to provide a complete characterisation of a mAb product using a single analytical tool.

Application of Multiparticulate Technologies for Drug Delivery
APPLICATION OF MULTIPARTICULATE TECHNOLOGIES FOR DRUG DELIVERY
Multiparticulates are a versatile group of dosage forms applicable to a broad range of drug delivery problem statements. Multiparticulates are highly flexible, capable of immediate release, modified-release (delayed, controlled, extended) enteric, bioavailability-enhancement, and taste masked releas...

[Webinar] A Closer Look at the Potential of CRISPR/Cas9 in Duchenne
[WEBINAR] A CLOSER LOOK AT THE POTENTIAL OF CRISPR/CAS9 IN DUCHENNE
On December 15, 2016, PPMD hosted a webinar with Dr. Eric Olson from the Department of Molecular Biology at UT Southwestern Medical Center to review the basics of gene editing and next steps in the research and development potential of CRISPR/Cas9 in Duchenne.

 Good Manufacturing Practices for Aseptic Filling of Biopharmaceuticals
GOOD MANUFACTURING PRACTICES FOR ASEPTIC FILLING OF BIOPHARMACEUTICALS
Sterilization is a critical process that packaging components undergo when processed via aseptic conditions. There are various sterilization processes and variables that are utilized to remove or destroy micro-organisms so that the end drug product is free of contagious hazards in all respects.

Biotech, Pharma, & Life Sciences at the USPTO
BIOTECH, PHARMA, & LIFE SCIENCES AT THE USPTO
Biotech, Pharma, & Life Sciences at the USPTO" is an in-depth examination of the state of patent prosecution in the biotechnology, pharmaceutical, and life sciences industry sectors using exclusive Juristat data. Some of the topics covered include handling rejections, drafting better claims...

Flexible BioPharma Manufacturing Now 7 24 14 2 00 PM
FLEXIBLE BIOPHARMA MANUFACTURING NOW 7 24 14 2 00 PM
As biopharmaceutical-processing platforms are moving from rigid stainless steel to flexible single-use technology, stable platforms create the ability to run processes more efficiently and with higher agility.

Webinar: Biomarker Challenges in Biosimilar Drug Development
WEBINAR: BIOMARKER CHALLENGES IN BIOSIMILAR DRUG DEVELOPMENT
Biosimilars are a cost competitive market. Pricing may have a direct impact on market share, and return on investment. It is important to have a robust and cost effective process. New high-density cell culture processes, such as concentrated perfusion, and flexible facilities with single-use technol...

Applications of Q-PCR and DNA Sequencing in the Detection and Identification of Adventitious Agents
APPLICATIONS OF Q-PCR AND DNA SEQUENCING IN THE DETECTION AND IDENTIFICATION OF ADVENTITIOUS AGENTS
Viral contamination, including MMV and Vesivirus, is a potential threat to mammalian cell culture manufacturing processes. Many cell culture manufacturing facilities have been negatively impacted following contamination with these viruses.

Objectionable Microorganisms in Biopharmaceutical Manufacturing webinar
OBJECTIONABLE MICROORGANISMS IN BIOPHARMACEUTICAL MANUFACTURING WEBINAR
This webinar will discuss the regulations pertaining to objectionable microorganisms, agency expectations, methods to identify objectionable microorganisms, interpreting results, and controls to put into place.

2017 BIO World Congress Partnering and Programming Webinar
2017 BIO WORLD CONGRESS PARTNERING AND PROGRAMMING WEBINAR
BIO One-on-One Partnering™ is the most efficient way to do business in the industrial biotechnology industry without traveling all over the world.

Webinar: Selection and Deployment of the MODA-EM™ Solution for BioMarin Pharmaceutical
WEBINAR: SELECTION AND DEPLOYMENT OF THE MODA-EM™ SOLUTION FOR BIOMARIN PHARMACEUTICAL
View the archived webinar and learn from the BioMarin Case Study how the MODA-EM™ Solution helps to successfully manage the specific needs of Environmental Monitoring (EM).

EURORDIS Genome Editing Webinar
EURORDIS GENOME EDITING WEBINAR
The webinar was moderated by Dr Virginie Bros-Facer, EURORDIS Research Infrastructure Project Manager and included presentations from  Professor Fulvio Mavilio, Scientific Director of Généthon, France, who talked about the science behind the therapeutic potentials for rare genetic...

Important Lessons in Developing Biosimilars Webinar
IMPORTANT LESSONS IN DEVELOPING BIOSIMILARS WEBINAR
In this recording of our September 28, 2011 webinar, Dr. Bob Roth, MD, Ph.D., Vice President, and Dr. Nick Fleischer, R.Ph., Ph.D., Vice President, The Weinberg Group Inc., help life science executives understand the market opportunity in pursuing biosimilars.

Risk of Presence of Objectionable Microorganisms in Biopharmaceutical Production
RISK OF PRESENCE OF OBJECTIONABLE MICROORGANISMS IN BIOPHARMACEUTICAL PRODUCTION
This webinar you will discuss how to help your organization get a better handle on what is an “objectionable microorganism, ” exactly how “objectionable” it really is and what you can do to minimize the risk if you find one in your process or product. The topic of “obje...

Keeping pace with immuno-oncology research breakthroughs and biomarker identification
KEEPING PACE WITH IMMUNO-ONCOLOGY RESEARCH BREAKTHROUGHS AND BIOMARKER IDENTIFICATION
In this webinar, Adrian Benjamin PhD, and Kimberly Robasky PhD detail how NGS technology can accelerate biomarker identification and bring down costs for research subject screening and safety monitoring – potentially making new treatments more effective. Among those technologies is RNA-Seq. Ad...

What
WHAT'S HOT & WHAT'S NOT IN IMMUNO ONCOLOGY LICENSING
This web panel discussion, hosted by ShareVault, Defined Health, Pullan Consulting, the Licensing Executives Society and the Biotechnology Industry Organization (BIO), discussed what's exciting and not so exciting in immuno-oncology drug development, and why.

Webinar Design of Experiments in biopharmaceutical development - Batavia Biosciences
WEBINAR DESIGN OF EXPERIMENTS IN BIOPHARMACEUTICAL DEVELOPMENT - BATAVIA BIOSCIENCES
In this webinar you will learn how to use DoE in planning your experiments and analyzing the data obtained. We will guide you through all phases of a DoE workflow and show you how Batavia Biosciences uses it to optimize USP and DSP development. So if you are interested in accelerating your biopharma...

DNASTAR - Solutions for De Novo Genome Assembly Webinar
DNASTAR - SOLUTIONS FOR DE NOVO GENOME ASSEMBLY WEBINAR
Selecting the right tools and software for performing de novo genome assembly is of vital importance, particularly given the relative ease of generating short-read sequence data. As you embark on a complex genome project, what do you need to know in terms of evaluating algorithms? DNA library prepar...

Rx-360 Webinar on Falsified Medicines Directive and API Importation into the EU
RX-360 WEBINAR ON FALSIFIED MEDICINES DIRECTIVE AND API IMPORTATION INTO THE EU
Rx-360 is a consortium being developed by volunteers from the Pharmaceutical and Biotech industry which includes their suppliers. The purpose is to enhance the security of the pharmaceutical supply chain and to assure the quality and authenticity of the products moving through the supply chain.

Strategic Market Analysis of Indian Biosimilar Market
STRATEGIC MARKET ANALYSIS OF INDIAN BIOSIMILAR MARKET
This Analyst Briefing will provide a brief overview of the Indian biosimilar market, highlighting the key trends, drivers, and restraints. It further highlights the emerging trends and market opportunities to enable decisions related to future strategies and investments in this segment.

Stem Cells - The Future of BioTech Part 1
STEM CELLS - THE FUTURE OF BIOTECH PART 1
Elaine Fuchs (born 1950) is an American cell biologist, famous for her work on the biology and molecular mechanisms of mammalian skin and skin diseases, and has led the modernization of dermatology. Fuchs also pioneered reverse genetics approaches, which assess protein function first and then assess...

Webinar: CRISPR-Cas9 gene editing with synthetic RNA - from start to finish
WEBINAR: CRISPR-CAS9 GENE EDITING WITH SYNTHETIC RNA - FROM START TO FINISH
The Dharmacon Edit-R CRISPR-Cas9 gene editing platform shortens the typical gene editing workflow by using synthetic guide RNA. This webinar provides background on CRISPR-Cas9 mediated gene editing and considerations for effective crRNA design, how to determine optimal transfection conditions, the u...

[Recorded Webinar] Scalability and Robustness of the Mobius® CellReady Bioreactor Platform
[RECORDED WEBINAR] SCALABILITY AND ROBUSTNESS OF THE MOBIUS® CELLREADY BIOREACTOR PLATFORM
Upstream processing is shifting to single-use bioreactors due to their advantages over traditional stainless steel reactors. The Mobius® single-use bioreactor platform consists of 3 L, 50 L and 200 L vessels that are scalable and robust in cell culture applications. This presentation will...

[Recorded Webinar] Delivering More Efficient Therapeutic Protein Expression Systems Through Cell Line Engineering Applications
[RECORDED WEBINAR] DELIVERING MORE EFFICIENT THERAPEUTIC PROTEIN EXPRESSION SYSTEMS THROUGH CELL LINE ENGINEERING APPLICATIONS
Historically cell line performance has been enhanced through media, feed and process optimization, primarily through trying to meet the basic nutritional requirements of the cells so that they can sustain high growth and productivity throughout the production runs.

Biotech Support Group - Protein Enrichment Webinar Series For Biomarker Discovery
BIOTECH SUPPORT GROUP - PROTEIN ENRICHMENT WEBINAR SERIES FOR BIOMARKER DISCOVERY
Biotech Support Group develops genomics and proteomics reagent kits for protein enrichment and/or depletion for biomarker discovery. Join us for a webinar on understanding why proteomics and genomic sample preparation is undergoing revolutionary advancements by technologies allowing scientists to im...

Emerging Trends in Academic and Industry Collaboration Webinar
EMERGING TRENDS IN ACADEMIC AND INDUSTRY COLLABORATION WEBINAR
Novel collaborations between industry and academia are driving the commercialization of the next generation of biomedical cures - Emerging trends and new models in technology transfer and translational research designed to help university inventions cross the "valley of death" - #BIO1x1 Pa...

Innovative Biosimilars Development Strategies
INNOVATIVE BIOSIMILARS DEVELOPMENT STRATEGIES
In this webinar, PPD experts discuss using a seamless development strategy, combined with a Bayesian statistical approach, to more accurately assess biosimilarity and potentially reduce development time and cost.

Rethinking the Traditional Western Blot - Introduction to an Alternative: In-Cell Western Assays
RETHINKING THE TRADITIONAL WESTERN BLOT - INTRODUCTION TO AN ALTERNATIVE: IN-CELL WESTERN ASSAYS
In this webinar, we describe the In-Cell Western Assay and its use in neuroscience research. The traditional Western blot protocol is streamlined, eliminating cell lysis, gel electrophoresis, and membrane transfer. The In-Cell Western Assay enables screening and analysis of many more samples in each...

Lasergene Weekly: Molecular Biology Webinar
LASERGENE WEEKLY: MOLECULAR BIOLOGY WEBINAR
In this webinar, DNASTAR’s Katie Maxfield will discuss our integrated software offering for molecular biologists. The session will include a live demonstration of workflows for virtual cloning, primer design, multiple sequence alignments, Sanger sequence assembly and analysis, and gene discove...

Webinar | Biosimilars 102
WEBINAR | BIOSIMILARS 102
The FDA approved the first biosimilar drug under the Biologics Price Competition and Innovation Act of 2009 (BPCIA) and the courts have recently rendered some important statutory interpretations. This represents the dawn of a new era in the approval and marketing of biologic products. Join Fish atto...

Bioenergy in the CPP Webinar: CPP Biomass Emissions Accounting
BIOENERGY IN THE CPP WEBINAR: CPP BIOMASS EMISSIONS ACCOUNTING
This presentation more specifically addresses the calculations in the EPA's Biogenic Emissions Accounting Framework, which recently completed a second round of review by the agency's Science Advisory Board. This will have significant implications once finalized by EPA on how state-level regu...

[Webinar] Leveraging Real World Data to Streamline Clinical Trials
[WEBINAR] LEVERAGING REAL WORLD DATA TO STREAMLINE CLINICAL TRIALS
Industry is encumbered with lengthy drug development timelines and high costs. These challenges are correlated with the difficulty to recruit appropriate patient populations for clinical trials. Join this session to learn how real world data is transforming the way biopharma, CROs and study sites na...